DAVID GRANOVSKY

Posts Tagged ‘skin’

Final step of pluripotency pinpointed!

In STEM CELLS IN THE NEWS on September 8, 2009 at 1:16 pm

Switching on the power of stem cells

21 August 2009

Scientists have uncovered a vital link in the chain of events that gives stem cells their remarkable properties.

Researchers from the Wellcome Trust Centre for Stem Cell Research at the University of Cambridge have pinpointed the final step in a complex process that gives embryonic stem cells their unique ability to develop into any of the different types of cells in the body (from liver cells to skin cells). Their findings, published today in the journal Cell, have important implications for efforts to harness the power of stem cells for medical applications.

via University of Cambridge.

Flab and freckles could advance stem cell research

In STEM CELLS IN THE NEWS on September 8, 2009 at 12:03 pm

Flab and freckles could advance stem cell research

Alternative tissues shown to yield reprogrammed cells aplenty.

Elie Dolgin

BellyFat cells are more easily turned into iPS cells than fibroblasts.

Fat cells and pigment-producing skin cells can be reprogrammed into stem cells much faster and more efficiently than the skin cells that are usually used — suggesting large bellies and little black moles could provide much-needed material for deriving patient-specific stem cells.

via Flab and freckles could advance stem cell research : Nature News.

Stem cell successes go unreported

In STEM CELLS IN THE NEWS on September 7, 2009 at 7:30 pm

“ADULT” Stem cell successes go unreported

Charlie Butts and Marty Cooper – OneNewsNow – 9/5/2009 4:10:00 AM

Medical Research – The Culture and Media Institute believes the media is biased in favor of research on human embryos, but that there is scant coverage of successful work with adult stem cells.

CMI’s Colleen Raezler says the media is playing upon emotions in its promotion of embryonic stem-cell research. “Reporter after reporter keeps touting the line that scientists believe that by turning embryonic stem cells into cells damaged by injury or disease, they can treat or even cure everything from spine cord injuries to Alzheimer’s disease to diabetes,” she notes.

She contends the media fails to mention that such research has proven nothing and has been scientifically ineffective.

Colleen Raezler”And they’re also ignoring the fact that adult stem-cell research has provided 73 different breakthroughs to help people with spinal cord injuries, with Alzheimer’s disease, with Parkinson’s, and with diabetes,” Raezler adds.

The CMI spokeswoman points out that adult stem cells can be taken from hair, skin, and fat and do not involve killing a tiny human being. Those successes, she laments, are not being reported in the media and should be.

via Stem cell successes go unreported (OneNewsNow.com).

Liposuction Fat Turns to Stem Cells Quicker Than Skin

In SCIENCE & STEM CELLS on September 7, 2009 at 5:37 pm

Liposuction Fat Turns to Stem Cells Quicker Than Skin in Study

By Rob Waters

Sept. 7 (Bloomberg) — Human fat, widely available and easily harvested with liposuction, morphed into stem cells more efficiently than skin cells in a study, giving scientists an alternative to the use of embryonic cells.

Three years ago, Shinya Yamanaka, of Kyoto University in Japan, showed that skin cells could be genetically manipulated to become any other cell type, much like embryonic stem cells. This process was hailed as avoiding the destruction of embryos and letting scientists create new therapies by making stem cells from patients who are ill.

Since then, researchers have sought to overcome two drawbacks to Yamanaka’s method. One is that the viruses and genes used to reprogram skin cells can trigger tumor growth. The second is that the process is inefficient, with less than 1 percent of skin cells becoming all-purpose cells. The new research, published today in the Proceedings of the National Academy of Sciences, may solve the second problem.

via Liposuction Fat Turns to Stem Cells Quicker Than Skin in Study – Bloomberg.com.

Insulin-Producing Cells From Adult Skin Cells

In ALL ARTICLES on September 1, 2009 at 3:04 pm

MONDAY, Aug. 31 (HealthDay News) — Using skin cells from people with type 1 diabetes, researchers were able to produce cells that made insulin in response to changing blood sugar levels, though not as efficiently as normal insulin-producing cells do.

The major immediate implication from this experiment is that scientists now have a preliminary lab model of human type 1 diabetes cells, and the hope is that an animal model of the disease could be developed from this research. Down the road, this finding could lead to a way to replace the islet cells that were destroyed when the disease first developed.

via Atlanta health, diet and fitness news | ajc.com.

New insights on eye stem cells

In STEM CELLS IN THE NEWS on August 31, 2009 at 11:44 am

New insights on eye stem cells

Retinal stem cell - Wallace group

Retinal stem cell – Wallace group Retinal stem cells have now been created from human skin, adding yet another specialized cell type to a rapidly growing list of cells that can be created using induced pluripotent (iPS) methodology. The finding could prove to be an important method in the production of human retinal cells, which would help overcome one of the greatest obstacles to successful stem cell therapies to treat eye conditions. The announcement was made on Monday by a team from the University of Wisconsin-Madison.

via Stem Cell Network Blog: New insights on eye stem cells.

Retina Cells Created From Skin-derived Stem Cells

In VICTORIES & SUCCESS STORIES on August 26, 2009 at 1:58 pm

A team of scientists led by David Gamm, assistant professor of ophthalmology and visual sciences, and Jason Meyer, research scientist, has successfully grown multiple types of retina cells from two types of stem cells — suggesting a future in which damaged retinas could be repaired by cells grown from the patient’s own skin. Pictured here in a microscopic photograph are early retinal cells (green) and early brain cells (blue). (Credit: Courtesy David Gamm)

Retina Cells Created From Skin-derived Stem Cells

ScienceDaily (Aug. 25, 2009) — A team of scientists from the University of Wisconsin-Madison School of Medicine and Public Health has successfully grown multiple types of retina cells from two types of stem cells — suggesting a future in which damaged retinas could be repaired by cells grown from the patient’s own skin.

via Retina Cells Created From Skin-derived Stem Cells.

George Hamilton – Hamilton Calms Fears Over Stem-Cell Injections – Contactmusic News

In STEM CELLS IN THE NEWS on August 25, 2009 at 10:09 pm

HAMILTON CALMS FEARS OVER STEM-CELL INJECTIONS

Movie veteran GEORGE HAMILTON is calming fears over stem-cell injections he receives to keep his tanned skin youthful – insisting human embryos are not involved in the controversial procedure.

The 70-year-old star is famous for his year-round bronzed complexion and admits he regularly gets the injections to avoid a shrivelled look.

However, Hamilton insists his ethics should not be questioned – because doctors merely plump his face with his own fat cells.

He tells the New York Daily News, “You don’t have to get it from embryos. You can get it from your own fat.”

via George Hamilton – Hamilton Calms Fears Over Stem-Cell Injections – Contactmusic News.

IZumi, Japanese university unite to refine stem cell technique – Related Stories – BIO SmartBrief

In ALL ARTICLES, BUSINESS OF STEM CELLS on April 14, 2009 at 8:12 pm

shake-on-it-japan-izumi bio

IZumi, Japanese university unite to refine stem cell technique

BIO SmartBrief | 04/14/2009

IZumi Bio in California is collaborating with Kyoto University in Japan to further develop and commercialize a technique for converting mature human cells into an embryonic like state. The procedure, known as cellular reprogramming, might lead to speedier drug discovery by allowing testing of experimental medicines against newly created cell lines from patients. Wall Street Journal, The (04/14)

via IZumi, Japanese university unite to refine stem cell technique – Related Stories – BIO SmartBrief.

Gairdner award honours noted stem-cell scientist

In ALL ARTICLES, VICTORIES & SUCCESS STORIES on March 31, 2009 at 2:06 pm
shinya-yamanaka-dr-skin-stem-cell

shinya-yamanaka-dr-skin-stem-cell

Gairdner award honours noted stem-cell scientist

Shinya Yamanaka among international researchers who will receive ‘baby Nobels’ in Canada this year

From Tuesday’s Globe and Mail,March 31, 2009 at 6:00 AM EDT

SCIENCE REPORTER

Shinya Yamanaka, the Japanese researcher who transformed skin cells from the wrinkled face of an 81-year-old man into stem cells, is one of this year’s winners of the prestigious Canada Gairdner Awards for medical research.

The awards, to be announced today, will be presented in Toronto in October. They are known as the “baby Nobels” because 73 winners over the past 50 years also became Nobel laureates.

Dr. Yamanaka discovered a way to reprogram adult cells so they regain the superhero-like abilities of embryonic stem cells, which give rise to every type of cell – blood, bone, brain and 250 other specialized cells that make up the human body.

via globeandmail.com: Gairdner award honours noted stem-cell scientist.

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