DAVID GRANOVSKY

Posts Tagged ‘placenta’

RUSSIAN PENCILS, IRON LUNGS AND GLASS HAMMERS

In STEM CELLS IN THE NEWS on October 8, 2015 at 12:40 pm
Don’t get me wrong. I love science. I am fascinated, jazzed and awed by what we can do with modern technology. It’s just that, every now and then, I feel like someone is really missing the boat and creating a very complicated solution for a simple problem.
TotheStars-matchbox-cover-1963
There’s a great story about how NASA spent millions to develop a pen which could write in zero gravity.  The punchline? The Russians just used a pencil.  Ironically, the Zero G Space Pen story isn’t true.  Lead pencils were used on all US Mercury and Gemini space flights and all Russian space flights prior to 1968.  In December 1967 Paul C. Fisher sold 400 zero G writing and NASA tested and approved Fisher Space Pens to NASA for $2.95 each.  He developed the Fisher Space Pen privately with his own money.  But is there something to learn here?  Are we missing the forest for the trees?  The pencil for the pen?  Are we overthinking and under working problems and coming up with solutions which are way more complicated than necessary?
iron-lung2
A TV show had this exchange:
JOEY:  “The Federal Government shouldn’t be directing scientific research.”
SAM:  “Why?”
JOEY:  “Because you stink at it. ‘If it was up to the NIH to cure polio through a centrally directed program. . . You’d have the best iron lung in the world but not a polio vaccine.'”
SAM:  “When did you get an M.D.?”
JOEY:  “I was just quoting Samuel Broder. . . . The former director of the National Cancer Institute.”
Sometimes we need to take a step back and view the problem, the whole problem, in a different way than we have been trained to, been conditioned to and been told to.
glass-hammer-and-nails
Imagine you needed a hammer.  So you went to a glass manufacturer to design and fabricate an awesome hammer. Why a glass manufacturer?
Maybe that’s all you know.
Maybe someone else told you you had to use them.
Maybe your were born in Plato’s cave and all you saw in front of you were glass manufacturers.

In any case, that’s where you went. So, after 8 years of research and $250 million you had the end all be all, most incredible, awesome-est unbreakable, high strength glass hammer in the world. Cool huh? What we can do is astounding… but at some point, shouldn’t we ask ourselves whether we are over complicating the problem?  Couldn’t you have gotten a regular hammer from the hardware store for $12.92.  Or used a rock.  Or the heel of your shoe.  And saved 8 years and a quarter million dollars.

lnc-rna-small
There is an article called “Small Non-Coding RNAs Can Cross The Placenta, Scientists Say” based on the Nanjing University study “Li et al. (2015) Small Non-coding RNAs Transfer Through Mammalian Placenta And Directly Regulate Fetal Gene Expression”  In it, researchers claim that small exogenous RNAs from plants eaten by a mother can cross the placenta and affect fetal development.  Further,
“Exogenous small RNAs in food not only affect pregnant female, but influence fetus development as well. The dietary patterns of the mother will influence the fetus or even determine the postnatal health status. Dietary bias or other unhealthy dietary habits would also affect the fetus health by disrupting the balance of transplacental miRNAs or even cause a fetus—origin adult disease. This finding also reveals the possibility that maternal small-noncoding RNAs participate in fetal epigenetic regulation during pregnancy. Thus, the pathological status of the mother will result in an abnormal endogenous miRNA profile per se, which will also influence fetal health.”
Fascinating.  What Mom eats can change the gene expression in the fetus, possibly even causing ‘origin adult disease.’
 
So what’s my issue?
Professor Hu Yali, from the department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital says:
“This finding also proposes a brand new potential strategy to treat fetal diseases in utero. Given that artificial synthetic siRNAs can transfer through placenta, we can try to use gene therapy to treat fetal disease by maternal administration,” Hu said.
 …
…or since small exogenous RNAs from plants eaten by a mother can cross the placenta and affect fetal development
…we could
…you know
…have pregnant moms eat more salads.
pregnant-woman-eating-salad

ROUND UP DAMAGES EMBRYONIC, PLACENTAL AND UMBILICAL CORD CELLS

In ALL ARTICLES, OFF THE BEATEN PATH, STEM CELLS IN THE NEWS on June 20, 2014 at 12:23 pm

roundup-the-ultimate-killing-machine

ROUND UP DAMAGES EMBRYONIC, PLACENTAL AND UMBILICAL CORD CELLS

Chemicals in Round Up are targeting both our reproductive abilities and our regenerative/healing abilities.  But we’ve know this for a long time.  What’s special about this article is that it is in Scientific American, “The leading source and authority for science, technology information and policy for a general audience”

From the article:
“Monsanto scientists argue that cells in Seralini’s study were exposed to unnaturally high levels of the chemicals…Seralini’s team, however, did study multiple concentrations of Roundup. These ranged from the typical agricultural or lawn dose down to concentrations 100,000 times more dilute than the products sold on shelves. The researchers saw cell damage at all concentrations.”

So while Monsanto scientists say the study used unnaturally high amounts, this is false,  The study included samples 100,000 TIMES MORE DILUTE than average exposures AND IT STILL CAUSED CELL DAMAGE.

Cell damage to

  • EMBRYONIC CELLS
  • PLACENTAL CELLS
  • UMBILICAL CORD CELLS

The corner stone to both our reproductive and regenerative capabilities.  Think you’re safe? Roundup Weedkiller Found In 75% of Air and Rain Samples, Gov. Study Finds

You idiots.  You’ve killed us all.

statue_planet

http://www.scientificamerican.com/article/weed-whacking-herbicide-p/

FRAUD, STEM CELLS, STANDARDS and FINDING THE RIGHT PATH

In BUSINESS OF STEM CELLS on October 16, 2011 at 11:19 am

This really pisses me off! 500 treatment centers out there and most of them are crap and they tarnish the entire industry!  I don’t know if this guy is a crook or not but this is why I recommend only 9 out of the 500 treatment centers. 

There are only 9 treatment centers that have passed a very rigorous set of standards.  Be careful out there guys! The benefits are huge but the path is windy and full of traps.  I’m happy to help those serious about getting treatment. 

Serious about getting treatment information? 

Fill out this form http://bit.ly/PATIENTQUESTIONNAIRE

Nevada doctor pleads not guilty in stem cell case
A prominent Las Vegas-area pediatrician pleaded not guilty Thursday to federal charges that he and a man who falsely claimed he was a doctor conspired to implant chronically ill patients with stem cells harvested from human placentas.

A lawyer for Dr. Ralph Conti issued a statement saying Conti was cooperating with federal authorities and “believes the facts of the case will unfold in a different fashion.”

Conti, 50, of Henderson, is accused of performing procedures on patients in Las Vegas in 2006 at the direction of Alfred Sapse. The indictment alleges that some patients became infected with unspecified ailments.

Prosecutors say Sapse had no medical license in Nevada or any state but operated a company called StemCell Pharma Inc. in Las Vegas.

The company solicited investors and patients with promises to use abdominal implants of placenta tissue to treat incurable diseases such as multiple sclerosis, cerebral palsy and the degenerative eye disease retinitis pigmentosa.

Sapse, now 85, was indicted in 2010 on 20 mail and wire fraud charges. He has pleaded not guilty. His federal public defender, Richard Boulware, declined to comment Thursday.

The indictment handed up Wednesday replaces the previous one against Sapse and leaves both Conti and Sapse facing 34 fraud and conspiracy charges.

“By misrepresenting his credentials, the nature of his treatment, the source of his `stem cells,’ and the adverse effects suffered by previous patients, defendant Sapse convinced chronically ill patients to undergo experimental implant procedures, many of which were performed by Conti,” the indictment said.

The document chronicles payments of $2,500 for implants and says the scheme reaped more than $1 million. Prosecutors allege that Sapse spent about $700,000 of the money on himself, including gambling sprees at Las Vegas casinos.

U.S. Magistrate Judge Carl Hoffman set trial for March 22. Both men could face decades in prison and millions of dollars in fines if convicted. The government also seeks the forfeiture of almost $914,000 it says is tied to the scheme.

Conti’s lawyer, Stan Hunterton, said outside court that Conti has six offices in the Las Vegas area and that he planned to continue to practice while awaiting trial.

“The matter relates to events that occurred five years ago and is unrelated to the pediatric medical practice he has operated successfully in Las Vegas for more than 20 years,” the statement said.

Prosecutors say Sapse claimed to be a retired physician who studied at the Filatov Institute of Eye Diseases and Tissue Therapy in Odessa, Ukraine.

The indictment alleges he hired Conti, who had no stem cell training, to perform placenta tissue implants on about 34 patients in Las Vegas from February to November 2006.

Prosecutors allege that several patients contracted infections, leading the federal Food and Drug Administration to issue a warning in November 2006 that alleged Sapse failed to properly obtain, store, test and process the placentas, or screen donors and patients.

A spokeswoman for U.S. Attorney Daniel Bogden declined to provide details about the infections, pending trial.

Three months after the FDA letter, Sapse moved his operation to Mexico and enlisted an unnamed physician in Nuevo Progresso who the indictment alleges performed about 100 implant procedures from February 2007 to May 2010.

Feds in Vegas charge man in stem cell surgery case – Friday, July 16, 2010 | 1:45 p.m. – Las Vegas Sun50

In STEM CELLS IN THE NEWS on July 16, 2010 at 8:41 pm

This kind of thing makes me so angry. Some guy practices without a license and tarnishes all of the legitimate stem cell treatment centers out there.  What an a$$! – dg

Feds in Vegas charge man in stem cell surgery case

The Associated Press

Friday, July 16, 2010 | 1:45 p.m.

Federal prosecutors in Nevada allege an 84-year-old Las Vegas man reaped about $1 million from patients and investors with claims that he was a retired physician with a stem cell medical procedure.

An indictment unsealed Thursday alleges Alfred Sapse had unidentified doctors in Las Vegas and Mexico perform experimental surgical implants of placential tissue in about 134 patients over the last four years.

Sapse pleaded not guilty to 20 mail and wire fraud charges. A U.S. magistrate judge let him remain free without bond. Trial was set Sept. 20.

An indictment says Sapse claimed to be a retired physician who studied in Ukraine, but had no medical license in Nevada or any other state.

It alleges Sapse created StemCell Pharma Inc. in May 2005 as part of the scheme.

via Feds in Vegas charge man in stem cell surgery case – Friday, July 16, 2010 | 1:45 p.m. – Las Vegas Sun.

Celebrity Baby Blog – People.com » David Charvet loading a box labeled, “Placenta”! «

In ALL ARTICLES, OFF THE BEATEN PATH on April 12, 2009 at 4:00 pm

The US has embraced a philosophy of disposability for many years…nothing was worth saving.  From relationships to buildings to our elderly; if it has outlived it’s usefulness, it is discarded.

It is nice to see that the concept of saving for the future is starting to make a come back.  People are saving and banking stem cells from cord blood, stem cells from milk teeth and now even placentas.  What do you do with a placenta? Read on… -dg

Placenta!

Check out this photo of new daddy David Charvet loading a box labeled, “Placenta” into the trunk of his car. What do you think he’s going to do with it?

https://i2.wp.com/img2.timeinc.net/people/i/cbb/archive/placenta.jpg

We guess that he and Brooke Burke might have a planting ceremony for their daughter Heaven Rain’s placenta! After all, a friend of Brooke’s says they chose the name because “Rain grows everything.”

Robin Elise Weiss, Pregnancy Guide on About.com, tells us…

The placenta is an amazing, disposable organ that helps sustain your pregnancy and baby throughout the nine months of pregnancy.  It grows from the time of conception to eventually take over the production of hormones needed to sustain the pregnancy at around 12 weeks gestation (from your last menstrual period). It supplies your growing baby with a means of obtaining nutrients for development as well as a method of waste disposal. This is the only disposable organ ever made.

Other cultures have come to see the placenta in a completely different light. There are even ceremonies and beliefs held about the placenta that are completely foreign to us.

Placenta planting ceremonies
One custom you do see in the US is burying the placenta in the ground to celebrate the new life given to them. This dedication of the placenta back to the earth or in honor of the child is becoming more frequent. A year later a tree or flower is then planted in the same spot to allow the placenta to nourish its growth. The reason that you would wait this year is that a placenta is so nutrient rich that it would kill anything planted before that period.

Lotus Birth
Some cultures practice a “Lotus Birth,” where the baby is left attached to the placenta until the cord dries up and falls off. It’s not often practiced in the US but is gaining popularity. The theories behind this are that it helps slow the new family down and offers them more seclusion in the first few days when a getting to know you period is in order. 

Placenta art
Generally mothers talk about placenta prints. After the birth you take a piece of paper and lay the placenta on it. If it is fresh you can let the blood and amniotic fluid leave the print or others choose to use paints to add color. Now what? Well, hang your framed art or store it for safekeeping.

Placentophagy
Eating the placenta is known as placentophagy. It is practiced by most mammals in the animal world, including many primates. This excludes the majority of humans.

However, there are some that proport that eating the human placenta can help with ailments from postpartum depression to postpartum hemorrhage.  There are some midwives and doctors who use the placenta medicinally in the early stages of postpartum because it is high in progesterone and has small amount of oxytocin. This supposedly helps stem bleeding after birth and causes the uterus to clean itself out.

There are even meal like recipes for cooking placentas, including placenta stew, placenta lasagna, power drinks with blended placenta and others. Though some mothers have been reported to eat placenta raw. For some placenta recipes, visit pregnancy.about.com.  (Caveat: While eating one’s own placenta doesn’t really pose any serious health risks, with the exception of spoilage, eating someone else’s placenta can be hazardous.)

Chinese medicine
Some forms of Chinese medicines also contain parts of human placenta. In Chinese Medicine, the placenta is known as a great life force and is highly respected in terms of its medicinal value. However, in this field it is not cooked, but rather usually dried. To dry a placenta you would simply dehydrate it in the oven, then using a mortar and pestle grind it up. From there you can mix it with food or ingest it within capsules. I have actually known one mother who did this drying technique. It is my only personal experience with placentophagia.

via Celebrity Baby Blog – People.com » Blog Archive Placenta! «.

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