DAVID GRANOVSKY

Posts Tagged ‘GI’

WHAT DOES THE FOXO1 SAY? HERE’S MORE INSULIN!

In ALL ARTICLES, BUSINESS OF STEM CELLS on July 5, 2014 at 10:20 am
It May Take Guts to Cure Diabetes -Human GI Cells Retrained to Produce Insulin

Imagine taking cells from your gastrointestinal tract and then switching off one gene, the FOXO1 gene, and then ending up with insulin producing cells.  From gut cell to diabetes fighter in one easy gene switch-off.  Scientists did this successfully in 2012 in mice and recently in humans.  What does the FOXO1 say? ‘Here’s more insulin!’  Awesome.

The next step is where it gets…awkward.  I’d like this information to generate a gene therapy protocol or to improve success rates in stem cell/Diabetes treatment protocols,  etc.  But that’s not the way our system works.  The next step is to find a drug that inhibits the FOXO1 gene so it “…could retrain cells inside a person’s GI tract to produce insulin…”  Unfortunately, this drug will also have side effects as all drugs do which will create other symptoms requiring other drugs to mitigate.  And so it goes.

When will US Diabetes patients be able to benefit from a medical protocol based on this discovery?  An educated guess puts it at:
7-10 years for clinical trials and drug development for a name brand Pharma product and then 10-15 years for the drug patent to open up to an affordable generic.
Sorry Diabetes patients.

New York, NY (June 30, 2014) “By switching off a single gene, scientists at Columbia University’s Naomi Berrie Diabetes Center have converted human gastrointestinal cells into insulin-producing cells, demonstrating in principle that a drug could retrain cells inside a person’s GI tract to produce insulin…The Columbia researchers were able to teach human gut cells to make insulin in response to physiological circumstances by deactivating the cells’ FOXO1 gene.”

Letters from Laura #1 – Autism, GI issues, chronic ear infections, breast cancer and Jenny McCarthy

In ALL ARTICLES, Letters from Laura on April 3, 2009 at 7:52 pm

jenny-mccarthy-son-autism

Dear David-

Two years ago, my son was 16 months old and having terrible GI issues and chronic ear infections. He only slept through the night 4 times. We had him vaccinated for his MMR and immediately following he was losing his speech. We took him to docs who told us to put him on a white flour diet, handed us lots of allergy drug samples, and told us to get tubes in his ears. i was so frustrated.

one day, my daughter put a puzzle piece into my laptop and it got stuck. My husband ran it over to a computer place for me, and had our son Walker. A man there was looking at Walker and began asking my husband questions….was he drinking milk, how was his speech, etc. He (Stan Kurtz) introduced my husband to his 5 year old very healthy son, and told him his son was diagnosed with autism at age 2 and severe autism at age 3. They said he would never be a functioning child.

Stan did research and then changed his sons diet, put him on anti-fungal medication and Valtrex (they say that autism is a combination of infections, viruses, metal toxicity and intestinal fungus.) I called him the next day and he spent 90 minutes on the phone with me. He shared with me what he fed his son. He never asked for anything, offered no controversial drugs, and suggested I get a pure form of Vitamin B12 called Methylcobalamin and get him started on that.

That day we started the diet (no wheat, grain, dairy, sugar) and that night my son slept through the night. The next night the same, and on Sunday, he began speaking. We went to an autism doc and started the B12 shots and his vocabulary tripled. His GI issues went away. He has never had an ear infection since. Now we keep him on this diet and it’s been over 2 years. His teachers have no idea there was ever an issue and he speaks like a 6 year old!

Stan works with over 2K families and started a school.  He also helped with the recovery of Jenny McCarthy’s son. i was talking to him one day and he asked about my health. He asked if i had any sisters or any history of breast cancer. I said no. He said that with all the families that he sees, there is an unusually high incidence of breast cancer, and the thought amongst docs is that the fungal issues contribute to breast cancer. The fungus tends to be the glue that holds cancer cells together.

Three weeks later, i was diagnosed with breast cancer.

I went through all the treatments, and I am doing great.  Stan has us all on a real detox program and we all follow the diet.

The reason I bring this long story up to you, is that there are thousands of families who are treating their children for autism with great results and you hear nothing about it. Jenny said she was expecting teams of medical doctors to bust down her door asking how she recovered her child from severe autism. Not one call.

-Laura

Related links:

http://www.generationrescue.org/

http://www.cnn.com/2008/US/04/02/mccarthy.autsimtreatment/index.html

http://www.huffingtonpost.com/2008/04/03/its-bullst-jenny-mccarthy_n_94854.html

http://www.babble.com/CS/blogs/famecrawler/archive/2008/03/08/jenny-mccarthy-s-autism-cure.aspx

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