In VICTORIES & SUCCESS STORIES on March 11, 2010 at 11:48 am
Autologous Bone Marrow Stem Cells Transplant into Parkinson’s Disease Patients is Safe and May Improve Their Quality of Life
Clinical study showing a minimally invasive approach was presented in The XVIII World Congress on Parkinson’s Disease and Related Disorders of the World Federation of Neurology.
(PRWEB) March 11, 2010 — Eight Parkinson’s Disease (PD) patients were treated with their own bone marrow stem cells (BMSC) injected via minimally invasive routes and discharged the next morning without complications.
Evaluations with UPDRS, Hoehn & Yahr scale and Schwab & England score showed encouraging improvements and the total L- dopamine dose could be decreased suggesting that stem cells may enhance endogenous dopamine synthesis. As a matter of sample, the writing test pre versus post procedure showed significant changes.
Eight Parkinson’s Disease (PD) patients were treated with their own bone marrow stem cells (BMSC) injected via minimally invasive routes and discharged the next morning without complications.
“It is high time we focused our efforts in what is possible and reachable and what suffering patients demand. Not all what is researched and developed in Petri dishes or rats can automatically be used in patients, so we should stop to augment their confusion. We expect this study in PD real patients, not in animals, draws the attention of those interested in getting clinical data since, funnily enough, there are billions of dollars spent in endless animal studies but very little in clinical ones” leader investigator Dr. Luis Geffner said.
- this is a tool that may complement standard treatments and delay the progress of both the illness and the complications of the medication currently used to treat it. PD patients should be cared comprehensively; therefore, their treatment may include physical therapies as well as optimal medication and stem cells transplant, trying to improve their independence and self-care he added.
- The treating doctor’s team has already transplanted 147 patients suffering from different illnesses or trauma states and many of them have been followed up 5 years showing that autologous adult BMSC neither provoke tumors, immunologic rejection, pain, infections nor arise ethical or religious controversies. That is why they stand to push these investigations forward.
- This clinical study Transplant of Autologous Bone Marrow Stem Cells into Parkinson’s Disease Patients Is Safe And May Improve Their Quality Of Life was shown in Miami on December 15th, 2009 in the XVIII World Congress on Parkinson’s Disease and Related Disorders organized by the World Federation of Neurology and published in December 2009 issue of Parkinson’s Disease and Related Disorders journal.
For more info on stem cells and Parkinson’s:
Muhammad Ali seeks ADULT STEM CELL treatment in Israel
60% PARKINSON’S PATIENTS IMPROVE AFTER REPAIR STEM CELL TREATMENT – PHYSICIANS CONFIRM RESULTS!
Do Stem Cells Repair Damaged Brain Cells
In ALL ARTICLES on February 16, 2010 at 1:35 pm
Scientists discover the secret of ageing
By Clive Cookson in London
Published: February 15 2010 23:00 | Last updated: February 15 2010 23:00
One of the biggest puzzles in biology – how and why living cells age – has been solved by an international team based at Newcastle University, in north-east England.
The answer is complex, and will not produce an elixir of eternal life in the foreseeable future.
But the scientists expect better drugs for age-related illnesses, such as diabetes and heart disease, to emerge from their discovery of the biochemical pathway involved in ageing.
The Newcastle team, working with the University of Ulm in Germany, used a comprehensive “systems biology” approach, involving computer modelling and experiments with cell cultures and genetically modified mice, to investigate why cells become senescent. In this aged state, cells stop dividing and the tissues they make up show physical signs of deterioration, from wrinkling skin to a failing heart.
In ALL ARTICLES, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on February 16, 2009 at 12:48 pm
“Heart disease patients in Britain could soon take part in a revolutionary stem cell surgery trial that could change the nature of heart surgery and ultimately end the need for transplants.” http://www.telegraph.co.uk/health/healthnews/4569971/Trials-for-revolutionary-stem-cell-surgery-in-UK-within-a-year.html That headline comes on the heels of President Obama’s promise to remove the ban from Government backed stem cell research here in the U.S.
The story by Caroline Gammell in the British publication, The Telegraph, seems to offer more than promise. If one could use their own stem cells to repair damaged organs it would be one of the greatest medical breakthroughs of all time. No long would there be a need for organ donors and sometimes risky transplant surgery. Also true is the fact that because a patient would use his or her own stem cells there would be no danger of rejection and therefore no need to take often toxic anti-rejection drugs that transplant patients must take for the rest of their lives. To quote from the story; “It is believed that British patents could take the pioneering treatment, in which a patient’s own cells are extracted and grown in a laboratory, in as little as a year. Scientists have worked out a technique where human bone marrow cells are turned into human heart stem cells and then injected into the heart. Laboratory grown heart stem cells were initially extensively tested on animals and trials on humans in Europe are due to start later this month (February 2009). “
THIS IS THE SAME PROCESS WHICH HAS BEEN USED IN GERMANY, THAILAND AND OTHER COUNTRIES FOR ALMOST A DECADE. -DG