DAVID GRANOVSKY

Posts Tagged ‘cocaine’

US is #1 in Stem Cell Research! …sort of…

In BUSINESS OF STEM CELLS, CATCH UP! on April 29, 2010 at 7:39 pm

We are #1!

With the release of new lines of embryonic stem cells, the US may reclaim their title as #1!  But #1 in what regard? Consumption of stem cells?  Not quite…

Consumption of embryonic stem cells?  Well, yes…but…

We are really only the leader in “consumption of embryonic stem cells used for research”.  But there is a reason for this.  Many countries have tried to research embryonic stem cells for treatment, for a decade or more, with full governmental and fiduciary support and then…given up.  Embryonic stem cells bring with them transplant rejection issues and grow into tumors and cysts.

We are in fact about 8 years behind most of the developed world in adult stem cell research; the only stem cells that have over half a decade of proven safety and efficacy.  So hooray for us!

What else are we #1 in?

We are the…

  • #1 consumer of the stem cells that have shown the least potential for treatment (embryonic)!
  • #1 consumer of environmentally damaging and war causing oil!
  • #1 consumer of cocaine (shipped from Colombia through Mexico and the Caribbean), Colombian heroin, and Mexican heroin and marijuana!

Here’s an idea, snarky as it may be…
What do you say we load up an SUV with cocaine and heroin, have a slammin party, OD on drugs and die young!  We might as well cause embryonic stem cells won’t produce cures for diseases anytime soon!

Not a bad idea, at least we could go out with a bang…If only we could afford it.

Our country’s bank account is more than $-568,800,000,000 ranking us 188th in the world.  Not to worry, we still have a good chance of dying before needing stem cells.  The WHO ranks our health system at 37th, our life expectancy is 30th in the world, infant mortality is 34th in the world and this is all with our Health Expenditures as a % of GDP being almost the highest in the world (we are ranked #2).   Now that’s money well spent.

And we’ll all probably be shot soon anyway.  We are ranked 78th in intentional homicides (and in this category, #1 is good).

HOORAY FOR THE U.S.A.! What’s not to love? – dg

THE US IS #1! -Another STEM CELL first for the US!

In ALL ARTICLES, CATCH UP!, STEM CELLS IN THE NEWS on March 25, 2009 at 1:26 pm

patriotic-poster - usa uncle sam

THE US IS #1! -Another first for the US!

The article below is entitled:

“The Leader in Stem Cell Research? The US.”

What a bunch of   *$&#X%!  We are only the leader in “consumption of embryonic stem cells used for research”.  We are in fact about 8 years behind most of the developed world in stem cell research.  What else are we #1 in?

#1 consumer of the stem cells that have shown the least potential for treatment (embryonic)!

#1 consumer of environmentally damaging and war causing oil!

#1 consumer of cocaine (shipped from Colombia through Mexico and the Caribbean), Colombian heroin, and Mexican heroin and marijuana!

What do you say we load up my SUV with cocaine and heroin, have a slammin party, OD on drugs and die young!  We might as well cause embryonic stem cells won’t produce cures for diseases anytime soon!

If only we could afford it.  Our country’s bank account is $-568,800,000,000 ranking us 188th in the world.  Not to worry, we still have a good chance of dying before needing stem cells.  The WHO ranks our health system at 37th, our life expectancy is 30th in the world, infant mortality is 34th in the world and this is all with our Health Expenditures as a % of GDP being almost the highest in the world (we are ranked #2).   Now that’s money well spent.

And we’ll all probably be shot soon anyway.  We are ranked 78th in intentional homicides (and in this category, #1 is good).

HOORAY FOR THE U.S.A.! What’s not to love? – dg

———————-

The Leader in (EMBRYONIC) Stem Cell Research? The US.

Which country gets the most embryonic stem cells for research?

The US.

The graph below comes from our research at Stanford (with my collaborators at Mayo Clinic and the University of Michigan), featured on the cover of the March issue of the journal Cell Stem Cell. We examined the world’s largest stem cell banks, in Wisconsin and at Harvard University. Twice as many shipments go to US researchers compared to rest of the world. The worldwide demand by scientists for embryonic stem cells is very strong. Way, way stronger than for credit default swap derivatives.

via The Leader in Stem Cell Research? The US. « The Stem Cell.

Injections of licorice ingredient show promise as treatment for cocaine addiction

In ALL ARTICLES, OFF THE BEATEN PATH on March 6, 2009 at 6:53 pm
Snorting Licorice?

Snorting Licorice?

An ingredient in licorice shows promise as an antidote for the toxic effects of cocaine abuse, including deadly overdoses of the highly addictive drug, researchers in Korea and Pennsylvania are reporting. Their study is in the 2 January issue of ACS’ Journal of Proteome Research, a monthly publication.

In the new study, Meeyul Hwang, Chae Ha Yang, and colleagues note that there is currently no effective medicine for treating cocaine abuse or addiction. Recent animal studies conducted by the researchers show that a licorice ingredient called isoliquiritigenin (ISL) can block the nervous system’s production of dopamine. That neurotransmitter is involved in emotion, movement, and other brain activities.

Cocaine and other addictive drugs stimulate dopamine and help produce the pleasurable and addictive effects. Drugs that block dopamine block this response. The scientists used rats as model animals to show that rats injected with ISL just prior to cocaine-administration showed 50 percent less of the behavioural effects associated with the illicit drug. They also showed that ISL injections protected nerve cells in the brain from cocaine-associated damage.

Source: American Chemical Society

via Science Centric | News | Injections of licorice ingredient show promise as treatment for cocaine addiction.

%d bloggers like this: