DAVID GRANOVSKY

Posts Tagged ‘clinic’

FDA GETTING INTO STEM CELLS?

In STEM CELLS IN THE NEWS on April 23, 2014 at 4:23 pm
https://repairstemcell.files.wordpress.com/2014/04/e6851-mk7.jpg
 
IS THE FDA FINALLY, PUBLICLY, GETTING INTO STEM CELLS?
Better late than never…14 years after serious adult stem cell research began in other parts of the world, the FDA finally woke up and they are beginning, BEGINNING to research adult stem cells. They even made a positive statement about their regenerative promise. We’ll call this one a victory in that the outcry for adult stem cells has been so loud, the FDA finally relented and have begun research. Better late than never. Thanks for coming to the party FDA…

But…14 years late to the party. Reminds me of the last scene in Schindler’s list. How many lives could have been saved? How much suffering could have been eased. Well, let’s do the math.

“…in 2005 there were 2,448,000 deaths in the u.s.
4 of the top 6 killers were:

Heart disease (652,000 deaths)
Cancer (559,000 deaths)
Stroke (143,000 deaths)
Diabetes (75,000 deaths)

There were a total of 1,429,000 deaths in 2005 from these 4 diseases and there are renowned stem cell treatment centers around the world that have been successfully treating patients with these disease for years. Around the world, people with these disease are actively receiving asc treatments and benefiting from them.

How many of those 1,429,000 deaths in the USA Could have been averted with asc treatment? How many of those 1,429,000 lives in the u.s. Could have been extended with asc treatment until other treatments were available? We’ll never know. Maybe we could have saved 30% of those people with asc or 428,700 people per year. Over 10 years that might amount to 4,287,000 people saved.

Saving 10% = 142,900 per year or 1,429,000 people saved in 10 years.
Even saving just 2% = 28,580 people per year amounts to 285,800 over 10 years.” [With a potential of 15,000,000 saved over 10 years.]
via https://repairstemcell.wordpress.com/stem-cells-101/

So when the FDA starts tooting their horn about showing up to the party, doing great research, working on unprecedented projects, the promise of adult stem cells and the ultimate success they will achieve…remind them they are doing so on the tail coats of the innumerable scientists, doctors and patients who have blazed the path before them…and please remind them to apologize to the millions who have died waiting for stem cell treatments in the USA. https://repairstemcell.wordpress.com/why-no-stem-cells-in…/

http://www.fda.gov/ForConsu…/ConsumerUpdates/ucm393030.htm

IMAGINE THERE WAS A STEM CELL INFORMER

In ALL ARTICLES on January 4, 2012 at 3:27 pm

Imagine there was a scientifically complicated subject which was difficult to understand even if you had all the information.  Imagine it would take you days, weeks, months to educate yourself on the subject.  Imagine the subject had more rampant misinformation published than virtually any other subject published in the last 5 years.  Imagine how long it would take you to assess the reams of conflicting information on the subject.  Imagine the subject was further mired in political and religious controversy.

Imagine there was a guy who spent years researching the subject, the science, the studies, the trials, the results, the protocols, the politics and the religious agendas.  Imagine he had one of the premier education blogs on the subject, lectured on the subject, wrote a book on the subject to promote awareness.  Imagine he worked with some of the world’s experts on the subject, wrote their websites and newsletters and internal communications so the layperson could understand the subject. Imagine this guy had an incredible network reaching out to all corners of the world.

Imagine that guy was willing to share all of his information with you free of charge and free of partiality. Imagine he just wanted you to know what your options were so you could make an educated decision just as he did.  Imagine he could shorten your research time logarithmically, he could get your medical data in front of the top stem cell docs in the world withing hours, he could get you an answer to whether you and your specific condition could be treated today or tomorrow.  Imagine he could introduce you to the Director of the Clinic so you could receive the treatment info, the protocol info, the travel info, the costs and the details.

Filling out the form bit.ly/stemcellsnow allows me to approach the top stem cell docs in the world quickly to see if you, with your specific condition, medical history, etc. are a candidate for treatment at their particular facility.  Your condition and needs determine where is best.

I am merely…a bridge or shortcut to get you to your destination with the minimum amount of confusion, time, effort and expense.

Maine Town Becomes First in US to Declare Food Sovereignty | Sustainable Cities Collective

In VICTORIES & SUCCESS STORIES on March 22, 2011 at 12:10 pm

Town secedes from governmental food control!  They can now produce, sell, consume whatever they want!  No GM foods or raw food restrictions, etc.  This is a great step towards people taking control of what they can eat and therefor, their own health.

“This four page ordinance, which can be read in its entirety here , is revolutionary in that it relies on the consumer to educate themselves on the risk of consuming products (such as raw milks, cheeses, meats and vegetables), and shifts the power away from regulation, which prevents people from eating food of their choosing.”

The conspiracy minded will say: Let’s hope “evil forces” don’t  go in and start e-coli epidemics there to “prove” people can’t be in control of their own health without dire consequences!

Indeed! -dg

https://i1.wp.com/www.ifood.tv/files/images/genetically-modified-food.jpg

Maine Town Becomes First in US to Declare Food Sovereignty | Sustainable Cities Collective.

ReNeuron – PRESENTS NEW DATA – STEM CELLS REPAIR BRAIN DAMAGE

In BUSINESS OF STEM CELLS on July 19, 2010 at 2:44 pm

ReNeuron presents new data showing how its stem cells work to repair brain damage. 12/07/10

Guildford, UK, 12 July 2010: ReNeuron Group plc (LSE: RENE.L) today announces important new data regarding the mechanisms of action of its lead CTX stem cell line in pre-clinical models of brain damage. The results of these studies will be presented in two posters1 at the UK National Stem Cell Network Annual Scientific Conference, taking place on 12 – 14 July, 2010 at the University of Nottingham, East Midlands Conference Centre, Nottingham, UK.

Image of stroke in the brain

In one series of studies, the angiogenic potential of the CTX stem cell line was tested, both in vitro and in rodent models of stroke damage. Angiogenesis is a multiple-step process whereby new blood vessels develop from pre-existing vasculature, potentially contributing to the functional recovery of the brain from damage such as that caused by ischaemic stroke. The results of these studies showed that the CTX cells express several trophic and pro-angiogenic factors in culture and also induce endothelial cell markers associated with blood vessel formation in the host at both 72 hours and 7 days post-implantation of the cells into the brain. Taken together, these results suggest that the CTX cells may play a role in promoting the functional recovery of stroke patients through up-regulation of angiogenesis in the region of ischaemic brain damage.

In a series of further studies, the CTX cells were seen to inhibit T cell activation. This immunosuppressive activity was in part attributed to the up-regulation of the ligand CD274, a regulator of T cell function. T cells are a type of white blood cell associated with the mediation of immune responses in the body. These results suggest that the CTX cells may act to suppress the inflammatory response associated with brain damage, thereby aiding the natural healing processes in the brain. This anti-inflammatory characteristic opens up a number of exciting new potential applications for the CTX cell line as a cell-based therapy for certain inflammatory diseases both within and beyond the brain.

ReNeuron recently announced the commencement of a UK Phase I clinical trial of its lead ReN001 stem cell therapy for disabled stroke patients. The ReN001 therapy represents the initial therapeutic application of the Company’s CTX stem cell line. Due in part to the anti-inflammatory properties of the CTX cells, patients in this clinical trial will not require immunosuppressive drug treatments alongside their cell therapy.

via ReNeuron –.

Former President of Argentina, Dr. Fernando de la Rua, Visits Colorado Stem Cell Therapy Clinic – Technology | Centre Daily Times – State College, PA | Penn State, Nittany Lions, weather, news, jobs, homes, apartments, real estate

In STEM CELLS IN THE NEWS on July 13, 2010 at 11:23 pm

Former President of Argentina, Dr. Fernando de la Rua, Visits Colorado Stem Cell Therapy Clinic

Respected leader seeks to take innovative stem cell therapy to Latin America

July 13, 2010 6:31pm EDT

HOUSTON — While in Denver, CO, to participate in the Transnational Summit of Former Heads of State with twelve other former Presidents, current government officials, and dignitaries during the Biennial of the Americas, the former Argentinean President, Dr. Fernando de la Rua, made a special trip to Broomfield, CO, yesterday to visit a stem cell therapy clinic. The visit, coordinated by David Bonner, Chairman & CEO of Stematix™, Inc., allowed Dr. De la Rua to tour the Centeno-Schultz Clinic, meet with the doctors and observe the Regenexx™ procedure performed on several patients.

Dr. de la Rua, former President of Argentina, former Mayor of the City of Buenos Aires, and a distinguished law professor, visited the clinic in order to better understand stem cell therapy and speak directly to the patients who are benefiting from the regenerative procedure that uses a person’s own stem cells to repair joints, ligaments, bone and tendons.

“The development of progressive, state-of-the-art stem cell therapy clinics in Latin America is something that I am very interested in,” said Dr. de la Rua. “My visit to the Centeno-Schultz Clinic solidified my belief that the use of adult stem cells in stem cell therapies is of great benefit to the general population.”

Adult stem cells are those found throughout the patient’s own body. Recent medical research has indicated these important cells have as much clinical promise as the more controversial embryonic stem cells (cells taken from an embryo).

“The Regenexx™ Procedure, using a person’s own stem cells, is a breakthrough, non-surgical treatment option for people suffering from moderate to severe joint or bone pain due to injury and other conditions” said David Bonner, Ph.D., Chairman & CEO of Stematix™, Inc. “Because of the reduced risk and significantly shortened recovery time, stem cell therapy is an ideal option for individuals around the world.”

About Stematix™, Inc.

Stematix™, Inc. (Houston, USA) is a regenerative medicine delivery company whose goal is to make regenerative medicine products and treatments available to patients at reasonable cost and to international medical standards. Stematix is a licensee for the Regenexx Procedure in Latin America. Please visit the Stematix website (www.stematix.com) for more information.

via Former President of Argentina, Dr. Fernando de la Rua, Visits Colorado Stem Cell Therapy Clinic – Technology | Centre Daily Times – State College, PA | Penn State, Nittany Lions, weather, news, jobs, homes, apartments, real estate.

Mayo Clinic + stem cell biotech

In STEM CELLS IN THE NEWS on September 2, 2009 at 11:45 am

Kiger’s Notebook – By Jeff Kiger, Post-Bulletin business columnist

September 01, 2009

Mayo Clinic-linked stem cell biotech = “Tremendous potential”

I’ve written about Cardio3, a Belgium biotech that is using Mayo Clinic research as part of its stem cell-based cardiac treatment, a few times before here and here.Today the company kicked out a release about its presentation at the European Society of Cardiology Congress in Barcelona, Spain. Here a little from the release:

————–

A unique second generation stem-cell derived therapy, C-Cure allows the differentiation of a patient’s own cells into ‘cardiopoietic’ cells which grow into new heart cells and repair heart muscle. C-Cure is currently undergoing a randomized, multi-center pivotal trial, designed to evaluate the safety and efficacy beyond optimal clinical care in patients with heart failure…

via Postbulletin.com: Rochester, MN.

MAYO CLINIC – STEM CELL – HEART

In VICTORIES & SUCCESS STORIES on August 1, 2009 at 1:49 pm

JULY 2009 NEWSLETTER

MEDICAL NEWS

I think the most stunning, positive news of the month is the work from the Mayo Clinic on stem cells and the heart. A few years ago I travelled to Thailand to visit with the King of Thailand’s cardiologist, Prof Supachai. Prof Supachai had developed a strong interest in adult stem cell therapy for heart disease. He was taking 200ml of blood from a person with severe heart failure and harvesting around 200,000 of the person’s own stem cells, growing the stem cells in a laboratory up to 20 million over a week and then reinjecting the stem cells into the damaged parts usually via a catheter directly down the arteries. I saw some amazing results with people who had severe impairment in their heart regaining reasonable function to allow them to return to relatively normal activity. The heart was not totally rebuilt but certainly much better than it was previously.

These types of results are being obtained all over the world and it is my strong feeling that adult stem cell therapy will be the next big revolution in medicine.

I am not a great fan of embryonic stem cell therapy, in the same way I am not a great fan of reproductive cloning, as I believe you cannot expect embryonic cells to behave like adult cells and I feel we will see some significant problems down the track if we start pushing this line. I have no problem with the ethics of it whatsoever, it is purely the science that I find rather questionable.

Now let’s return to the more valid concept of enhancing your own blood using adult stem cell therapy. The researchers from the Mayo Clinic (again we’re picking on the poor old mice this week) took a group of mice with damaged hearts and took their own cells, known as fibroblasts which are usually part of the connective tissue or seen in scars, and used a process called dedifferentiation. This is where the fibroblasts are converted back to stem cells. They then were able to give these particular stem cells growth factors that sent them along the pathway of becoming heart tissue. They reinjected these cells back into the mice and within a few weeks the mice were developing functioning cardiac tissue.

Once this technique is perfected for humanity, we will see many people salvaged from not just heart disease but also many other conditions, such as Parkinson’s disease, diabetes and spinal cord damage.

I am on the Scientific Advisory Board for an international company known as Zoa Cell and this company is embarking on a large study in diabetes using adult stem cell therapy. Again, taking one’s own stem cells, it will be possible to give growth factors to convert these into pancreatic tissue making insulin. Can you image the suffering that will be alleviated if all of these therapies become freely available.

Thank you for helping me help you.

Kind regards,
Dr Ross G T Walker (FRACP)
Consultant Cardiologist

http://www.drrosswalker.com/

CATCH UP! – Stanford gets $5.8M stem cell grant – San Francisco Business Times:

In ALL ARTICLES on April 30, 2009 at 3:40 pm
catch-up already

CATCH UP ALREADY

Wednesday, April 29, 2009, 4:45pm PDT

Stanford gets $5.8M stem cell grant

San Francisco Business Times

Researchers at Stanford University’s School of Medicine got a $5.8 million grant from the California Institute for Reenerative Medicine to look for ways to stimulate adult stem cells to heal damaged nerves, bone skin and cardiac muscle.

The grant was one of 15 given out worth a total of $67.7 million as part of CIRM’s Early Translational Research Awards program, which aims to move promising research from the lab to the clinics.

CIRM has given Stanford a total of $107 million from CIRM, including this most recent grant.

The board of the institute was reluctant to fund projects at their last two meetings prior to the one on Wednesday, but once the state was able to conduct a successful bond sale and raise $6.5 billion — $275 million of which went to CIRM — the institute was able to pay off a prior state loan and give out grants.

via Stanford gets $5.8M stem cell grant – San Francisco Business Times:.

CATCH UP! – Pfizer Joins British Researchers In Search For Eye Condition Cure

In ALL ARTICLES, BUSINESS OF STEM CELLS on April 30, 2009 at 3:39 pm

catch-up

By PETER BENESH, INVESTOR’S BUSINESS DAILYPosted 04/29/2009 06:38 PM ET

The good news is, you’re likely to live longer than your ancestors. The bad news: You’ll have longer to cope with the consequences of aging.

One issue is age-related macular degeneration, a condition that in the worst cases can reduce vision to near-blindness. Researchers in Britain, now in partnership with U.S. drug giant Pfizer (PFE), are working on a treatment. And it uses stem cells.

Pete Coffey, a professor at the University College London Institute for Ophthalmology and leader of the London Project to Cure Blindness, hopes to head off controversy over use of embryonic stem cells.

via Investors.com – Pfizer Joins British Researchers In Search For Eye Condition Cure.

Research ban is lifted on cloned human stem cells – INSIDE JoongAng Daily

In ALL ARTICLES on April 30, 2009 at 3:38 pm
dolly-sheep-cloning

dolly-sheep-cloning

April 30, 2009

Korea’s bioethics authority yesterday conditionally lifted a three-year ban on research using cloned human stem cells. The decision will allow scientists to resume studies that could lead to new ways of treating a variety of physical disabilities and diseases.

The lifting comes three years after the Health Ministry banned this kind of stem cell research following revelations that research by the celebrated scientist Hwang Woo-suk was fraudulent. Cha Medical Center, based in Seoul, applied for approval last October for research on cloning human embryos and extracting stem cells, claiming that its work could be crucial in developing effective treatments for Parkinson’s disease, stroke, spinal injuries, diabetes and cardiovascular disorders, among others.

However, the presidential committee on bioethics said research centers have to meet four conditions before their projects get a green light. The committee stipulates leaving out “treating diseases” from research proposals to avoid raising people’s expectations too high. The committee also demanded that the medical center obtain written agreements from egg donors and minimize the use of human eggs.

via Research ban is lifted on cloned human stem cells – INSIDE JoongAng Daily.

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