DAVID GRANOVSKY

Posts Tagged ‘autism’

LEAKY GUT + BLOOD BRAIN BARRIER =AUTISM?

In DISEASE INFO, HEALTH AND WELLNESS, SCIENCE & STEM CELLS on January 24, 2017 at 10:55 am

leaking

Does leaking cause autism and schizophrenia?

Remember those hysterical soccer Moms who said Autism has to do with the gut, the immune system and the brain.  Guess what, they were pretty spot on…it looks like in ASD and schizophrenia patients, there is a significant incidence of leaking in both the intestines and the blood-brain barrier

  1. “Blood-brain-barrier integrity and function and with inflammation was detected in ASD tissue samples, supporting the hypothesis that an impaired blood-brain barrier associated with neuroinflammation contributes to ASD”
  2. Gut: “75 percent of the individuals affected by ASD had reduced expression of barrier-forming cellular components, compared with controls, and 66 percent showed a higher expression of molecules that increase intestinal permeability”

autism-awareness

Wednesday, January 18, 2017

Study finds alterations in both blood-brain barrier and intestinal permeability in individuals with autism

Autism spectrum disorder (ASD) has the dubious distinction of being the fastest-growing developmental disability in the U.S., according to the Centers for Disease Control and Prevention. With 1 in every 68 children born in this country diagnosed with ASD, parents are looking everywhere for answers about best treatments. Along with selective medication to treat certain symptoms, traditional treatments include intensive behavioral approaches. But with no “one-size-fits-all” treatment approach, parents often turn to diverse complementary and alternative therapies.

Just as parents are looking for answers, scientists are trying to tease out the causes of this multifactorial and complex condition. “Although we are fairly certain that there is a genetic component, there are many pathways for an individual to arrive at autism’s final destination,” says Alessio Fasano, MD, director of the Center for Celiac Research and Treatment at Massachusetts General Hospital (MGH) and co-senior author of a study published in the journal Molecular Autism. “What might dispose one person to develop ASD – either pre- or post-natally – might have no such effect on another person,” he adds.

Looking at the interconnectivity of the gut-brain axis – the biochemical signaling between the gastrointestinal and central nervous systems – researchers led by Maria Rosaria Fiorentino, PhD, of the Mucosal Immunology and Biology Research Center at MassGeneral Hospital for Children (MGHfC), have opened up a new avenue of research into the pathophysiology of ASD and other neurodevelopmental disorders. “As far as we know, this is the first study to look at the molecular signature of blood-brain barrier dysfunction in ASD and schizophrenia in samples from human patients,” says Fiorentino. In collaboration with researchers from the University of Maryland School of Medicine and others, Fiorentino’s group found an altered blood-brain barrier in tissue samples from people with ASD when compared with healthy controls.

The group analyzed postmortem cerebral cortex and cerebellum tissues from 33 individuals – 8 with ASD, 10 with schizophrenia and 15 healthy controls. Altered expression of genes associated with blood-brain-barrier integrity and function and with inflammation was detected in ASD tissue samples, supporting the hypothesis that an impaired blood-brain barrier associated with neuroinflammation contributes to ASD.

In keeping with the hypothesis that the interplay within the gut-brain axis is a crucial component in the development of neurodevelopmental disorders, the group also analyzed intestinal epithelial tissue from 12 individuals with ASD and 9 without such disorders. That analysis revealed that 75 percent of the individuals affected by ASD had reduced expression of barrier-forming cellular components, compared with controls, and 66 percent showed a higher expression of molecules that increase intestinal permeability.

The study was driven in part by the high number of gastrointestinal problems that occur in people with ASD. Although considered controversial by some health care practitioners, a gluten- and casein-free diet has been shown to produce some improvement in behavioral and gastrointestinal symptoms in a subgroup of children with ASD. “This is the first time anyone has shown that an altered blood-brain barrier and impaired intestinal barrier might both play a role in neuroinflammation in people with ASD,” says Fiorentino.

Fasano adds, “As well as information on the blood-brain barrier, we were looking for more information on how increased intestinal permeability, otherwise known as a ‘leaky gut,’ might affect the development of ASD in the context of a dysfunctional gut-brain axis.”

Fiorentino’s next project involves looking more mechanistically at how microbiota – the collection of microorganisms in the gut – are linked with intestinal permeability and behavior. “There is definitely something going on between the gut and the brain with ASD and other neurodevelopmental disorders, and of course the microbiome has a big role to play,” she says. “It has already been shown that ASD kids have an altered composition of gut microbial communities. If we can figure out what is required or missing, then maybe we can come up with a treatment that might be able to improve some of the behavioral issues and/or the gastrointestinal symptoms.”

Fasano is a professor of Pediatrics, and Fiorentino is an assistant professor of Pediatrics at Harvard Medical School. Additional co-authors of the Molecular Autism paper are Anna Sapone, PhD, Stefania Senger, PhD, and Stephanie Camhi, MGHfC Mucosal Immunology and Biology Research Center; Sarah Kadzielski, MD, and Timothy Buie, MGHfC Gastoenterology and Lurie Center for Autism; Deanna L. Kelly, PharmD, BCPP, University of Maryland School of Medicine, and Nicola Cascella, MD, Sheppard Pratt Health System, Baltimore.

Massachusetts General Hospital, founded in 1811, is the original and largest teaching hospital of Harvard Medical School. The MGH Research Institute conducts the largest hospital-based research program in the nation, with an annual research budget of more than $800 million and major research centers in HIV/AIDS, cardiovascular research, cancer, computational and integrative biology, cutaneous biology, human genetics, medical imaging, neurodegenerative disorders, regenerative medicine, reproductive biology, systems biology, photomedicine and transplantation biology. The MGH topped the 2015 Nature Index list of health care organizations publishing in leading scientific journals and earned the prestigious 2015 Foster G. McGaw Prize for Excellence in Community Service. In August 2016 the MGH was once again named to the Honor Roll in the U.S. News & World Report list of “America’s Best Hospitals.”

SYSTEM CONNECTING BRAIN TO IMMUNE SYSTEM FOUND – AUTISM RECONSIDERED?

In ALL ARTICLES on September 16, 2015 at 11:47 am
“In contradiction to decades of medical education, a direct connection has been reported between the brain and the immune system….It seems astonishing that, after centuries of dissection, a system of lymphatic vessels could have survived undetected.”

EVERY time I have a conversation with someone who is 100% sure, I laugh inside and remember that everything we know for sure will be disproved within our lifetimes.
 
Medical science was 100% sure:
the heart doesn’t regenerate…wrong
the brain and central nervous system doesn’t regenerate…wrong
all of the ligaments have been found…wrong
butter is healthier, margarine is healthier, butter, margarine…wrong
stem cells don’t work…wrong
cholesterol is bad…wrong
and on and on and on and now…
 
This changes everything.

“It changes entirely the way we perceive the neuro-immune interaction,” says Kipnis. “We always perceived it before as something esoteric that can’t be studied. But now we can ask mechanistic questions.”

MS is known to be an example of the immune system attacking the brain, although the reasons are poorly understood. The opportunity to study lymphatic vessels that link the brain to the immune system could transform our understanding of how these attacks occur, and what could stop them. The causes of Alzheimer’s disease are even more controversial, but may also have immune system origins, and the authors suggest protein accumulation is a result of the vessels failing to do their job.

Indeed, Kipnis claims, “We believe that for every neurological disease that has an immune component to it, these vessels may play a major role.”

This changes everything.

Every single study dealing with brain and immune and GI systems must be revisited and re-evaluated.

For example, it begs the question…With so many people saying Autism is a neurological malfunction and so many people saying Autism is immune system caused and so many saying it is nutritional and heavy metal toxin caused…if these systems are all interconnected, perhaps they are all right.  Is it time to reconsider the cause (causes!) of Autism?

http://www.iflscience.com/brain/vessels-found-connect-immune-system-and-brain

MMR VACCINE AND AUTISM – THE SCIENCE

In ALL ARTICLES, OFF THE BEATEN PATH on April 30, 2013 at 6:56 pm

autism scientific america

TRYING TO GET A HANDLE ON THE MMR/VACCINE CONTROVERSY:

I don’t know what causes Autism but I believe in education, knowledge and research.

———————————————————————————–

Baby monkeys given standard doses of popular vaccines develop autism symptoms

“…a macaque monkey (primates) study of the very same vaccines given to children during 1994-1999, i.e., the Measles-Mumps-Rubella (MMR) vaccine and several Thimerosal mercury-containing vaccines injected into children during that time frame when the autism spectrum disorder skyrocketed.”

The original Study here:

Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study   http://www.ane.pl/pdf/7020.pdf

———————————————————————————–

WHAT ARE THE ADVERSE REACTIONS FROM MMR VACCINES?
http://www.merck.com/product/usa/pi_circulars/m/mmr_ii/mmr_ii_pi.pdf
(The warnings from the manufacturer are scary enough, even if it doesn’t cause autism.)

———————————————————————————–

WORLD STUDIES ON MMR/AUTISM:

Here is a list of 28 studies from around the world from (mercola.com) that support Dr. Wakefield’s controversial findings:

  1. The Journal of Pediatrics November 1999; 135(5):559-63
  2. The Journal of Pediatrics 2000; 138(3): 366-372
  3. Journal of Clinical Immunology November 2003; 23(6): 504-517
  4. Journal of Neuroimmunology 2005 
  5. Brain, Behavior and Immunity 1993; 7: 97-103
  6. Pediatric Neurology 2003; 28(4): 1-3
  7. Neuropsychobiology 2005; 51:77-85
  8. The Journal of Pediatrics May 2005;146(5):605-10
  9. Autism Insights 2009; 1: 1-11
  10. Canadian Journal of Gastroenterology February 2009; 23(2): 95-98
  11. Annals of Clinical Psychiatry 2009:21(3): 148-161
  12. Journal of Child Neurology June 29, 2009; 000:1-6
  13. Journal of Autism and Developmental Disorders March 2009;39(3):405-13
  14. Medical Hypotheses August 1998;51:133-144.
  15. Journal of Child Neurology July 2000; ;15(7):429-35
  16. Lancet. 1972;2:883–884.
  17. Journal of Autism and Childhood Schizophrenia January-March 1971;1:48-62
  18. Journal of Pediatrics March 2001;138:366-372.
  19. Molecular Psychiatry 2002;7:375-382.
  20. American Journal of Gastroenterolgy April 2004;598-605.
  21. Journal of Clinical Immunology November 2003;23:504-517.
  22. Neuroimmunology April 2006;173(1-2):126-34.
  23. Prog. Neuropsychopharmacol Biol. Psychiatry December 30 2006;30:1472-1477.
  24. Clinical Infectious Diseases September 1 2002;35(Suppl 1):S6-S16
  25. Applied and Environmental Microbiology, 2004;70(11):6459-6465
  26. Journal of Medical Microbiology October 2005;54:987-991
  27. Archivos venezolanos de puericultura y pediatría 2006; Vol 69 (1): 19-25.
  28. Gastroenterology. 2005:128 (Suppl 2);Abstract-303

———————————————————————————–

Dr. Wakefield’s Latest: MMR And Autism

http://articles.mercola.com/sites/articles/archive/2008/01/02/mmr-and-autism-part-two.aspx

References/Notes

1. Plotkin SA, Mortimer EA. (eds.) Vaccines, Philadelphia, W. B. Saunders, 1994. This collection of articles has a wealth of medical information about vaccines.

2. See details at http://www.cdc.gov/nip/registry.

3. “The effect of routine infant vaccination on acute disease incidence may not be apparent for 20-30 years because currently most infections occur among young adults.” Morbidity and Mortality Weekly Report, Vol. 44, No. 30, Aug. 4, 1995.

4. “In a sudden reversal of health policy, France has decided to suspend Hepatitis B vaccinations in secondary schools because of fears that the vaccine causes neurological disorders.” New York Times, Oct. 3, 1998.

5. ACIP meeting minutes, Feb. 1998. Available from CDC.

6. The Economist 1998;344(8044):95(3). It suggested possible correlations between vaccines and other diseases such as asthma.

7. Patton CV, Sawicki DS. Basic Methods of Policy Analysis, Prentice Hall, 1993.

8. ACIP Policies and Procedures, July 1998. Available from the CDC or from Some other supporting evidence on immunization policy is also there.

———————————————————————————–

Measles-Mumps-Rubella (MMR) Vaccine as a Potential Cause of Encephalitis (Brain Inflammation) in Children

http://articles.mercola.com/sites/articles/archive/2008/01/02/mmr-vaccine-part-three.aspx

References for this article:

1. Statements by Bernard Rimland, PhD, were given at a conference on autism, sponsored by the Autism Research Institute in Chicago, June, 1996.

2. Information from the Developmental Delay Registry, 6701 Fairfax Road, Chevy Chase, Maryland 20815, Tel. 301652-2263.

3. From a paper distributed by Dawbarns Law Firm, Bank House, Kingrs Staithe Square, Lingrs Lynn, Norfolk PE30 IRD, Great Britain, Tel. 01553. 764373, Fax 01553-765226.

4. Singh VJ et al., Antibodies to myelin basic protein in children with autistic behavior, Brain, Behavior, and Immunity, Vol. 7, 97-1203, 1993.

5. Kumar S & Miller LK, Effects of serial passage of Autographs Californica nuclear polyhidrosis virus in cell culture. Virus Research, Vol. 7, 335-349, 1987.

6. Jahnke U et al., Sequence homology between certain viral proteins and proteins related to encephalomyelitis and neuritis, Science, Vol. 29, 282-284, July 19, 1985,

7. Presentation by Dr. Vijendra Singh, August 16, 1997, Allegro School, Cedar Knolls, New Jersey.

8. Scott HD et al., Physician reporting of adverse reactions: results of the Rhode Island adverse drug reaction reporting project, JAMA, Vol. 263, No. 13, 1785-1788, April 4, 1990.

9. Reporting side effects: signals or noise? (Editorial), ibid, page 1823.

10. Gupta S et al., Dysregulated immune system in children with autism; beneficial effects of intravenous globulin on autistic characteristics, J ofAutism and Develop Disorders, Vol. 26, No. 4, 439-452, 1996. (In this article on page 450, it is stated, “We theorized that the high titers of rubella antibody … present in mothers of children with autism would be transplacentally transferred and may persist for a prolonged period in the child. When such a child gets MMR immunization, rubella antigen may complex with preexisting antibodies and such complexes might play a role in pathogenesis of autistic features.”)

11. Dublin L & Lotka A, Twenty-five Years ofHealth Progress, New York: Metropolitan Life Insurance Company, 1937, page 48.

12. Dublin L, Health Progress 1936-1945, New York: Metropolitan Life Insurance Company, 1948, page 12.

13. Vaccination. 100 Years of Orthodox Research Shows that Vaccines Represent a Medical Assault on the Immune System, Viera Scheibner, PhD., 1993 (from pages 33 to 49 the author extensively reviews the Swedish and Japanese experiences with the pertussis vaccine, book available from New Atlantean Press, P.O. Box 9638-925, Santa Fe, New Mexico 87504).

14. Garenne M et al., Child mortality after high-titre measles vaccines; a prospective study in Senegal, Lancet, Vol. 338, 903-907, October 12, 1991.

15. Hussey GD et al., The effect of Edmonston-Zagreb and Schwarz measles vaccines on immune responses in infants, J of Infect Diseases, Vol. 173, 1320-1326, 1996.

———————————————————————————–

Italian court reignites MMR vaccine debate after award over child with autism

http://www.independent.co.uk/life-style/health-and-families/health-news/italian-court-reignites-mmr-vaccine-debate-after-award-over-child-with-autism-7858596.html?origin=internalSearch

Original Articles in Italian:

MMR e Autismo: il caso Wakefield come emblema del “COVER-UP scientifico”

… per tutte sulla vicenda Wakefield e la correlazione fra MMR e Autismo. Innanzitutto vi segnaliamo il pregevole lavoro che il sito … i n discussione la procedura di valutazione dei vaccini MMR in Gran Bretagna fin dal lontano 1987 e conferma la sostanziale assenza di …

News – thinknew – 28/09/2012 – 08:05 – 0 comments – 1 allegato

MMR: la Vittoria di una Madre

… apparso il 16 giugno 2012 su “Daily Mail” con il titolo “MMR: A mother’s victory. The vast majority of doctors say there is no link …

Articolo – thinknew – 24/09/2012 – 13:17 – 0 comments – 0 allegati

Ascolta il Silenzio – Film

… i possibili legami tra la somministrazione del vaccino MMR, la malattia intestinale cronica e l’autismo.   Nonostante tutte le …

Argomento di discussione del forum – yellowbrain – 26/03/2013 – 19:58 – 0 comments – 0 allegati

Re: VACCINI OMEOPATICI

… 7 th November 1997″ , che riporta : ” MMR e SSPE ****** In una conferenza negli Stati Uniti, … potrebbe essere utile. ” originale: “MMR and SSPE****** at a conference in the US had suggested that the measles …

Commento – Lucas – 16/01/2013 – 00:19 – 0 comments – 0 allegati

Chi ha paura dell’uomo nero?

… di Valentino ( http://www.comilva.org/danno_da_vaccino/mmr_vittoria_di_madre ) poi dà particolarmente fastidio perché sbugiarda …

News – thinknew – 28/01/2013 – 11:35 – 0 comments – 0 allegati

Anonimo:Autismo e vaccino di MMR (orecc.morb.rosolia)

… sul collegamento di tale malattia con il vaccino di MMR (orecchioni – morbillo – rosolia). di: VICKY COLLINS Gordon Bell, … molto stretta tra l’autismo ed il vaccino di MMR(orecchioni – morbillo – rosolia) indicando che i bambini autistici … volta presenti a livelli così elevati, causa il vaccino MMR, scatenano in un organismo così debole nel sistema immunitario come quello …

Argomento di discussione del forum – OldForum – 30/07/2002 – 00:00 – 0 comments – 0 allegati

Anonimo:Il legame tra MMR e autismo.

… prove schiaccianti relative al legame fra la vaccinazione MMR (orecchioni – morbillo – rosolia) l’autismo e le malattie intestinali nei … urgentemente nuovi parametri sulla sicurezza del vaccino MMR – la vaccinazione combinata per orecchioni, morbillo e rosolia che viene …

Argomento di discussione del forum – OldForum – 02/08/2002 – 00:00 – 0 comments – 0 allegati

Londra. 40 bambini uccisi dal vaccino MMR

… (Discussioni Libere) …

Argomento di discussione del forum – alsa – 11/12/2010 – 11:50 – 0 comments – 0 allegati

Anonimo:ProQuad il nuovo vaccino MMR+ sicuro.

… bambini sono stati sottoposti ad iniezione del vaccino di Mmr (morbillo parotite rosolia), e una seconda iniezione di Varivax …

Argomento di discussione del forum – OldForum – 15/04/2003 – 00:00 – 3 comments – 0 allegati

Richiamo vaccinazione MMR

Ho appena scoperto il vostro forum e ne approfitto subito per chiedervi un’opinione: ho ricevuto la lettera della ASL (provincia di Milano) in cui mi invitano a presentarmi con il mio bambino di 6 anni per il richiamo di Morbillo-Rosolia-Parotite. Allegan …

———————————————————————————–

RELATED ARTICLES:

FAKE AND FRAUDULENT SCIENCE

CDC VACCINE COVER UP – MERCURY ACTUALLY DOES CAUSE AUTISM?

AUTISM RETROSPECTIVE

Letters from Laura #1 – Autism, GI issues, chronic ear infections, breast cancer and Jenny McCarthy

AUTISM/ASPERGER’S + STEM CELLS

AUTISM SPECTRUM, TREATMENTS AND CURES(?)

In ALL ARTICLES, OFF THE BEATEN PATH on April 30, 2013 at 10:13 am

autism-not-a-disease

What is the Autism Spectrum? What does it mean to Treat? Does treat mean Cure?

Let’s be clear, as clear as we can. Nothing applies to all but we speak of an autistic spectrum, a gross lumping together of many different variations.

“A spectrum (plural spectra or spectrums[1]) is a condition that is not limited to a specific set of values but can vary infinitely within a continuum…the autism spectrum. In these uses, values within a spectrum may not be associated with precisely quantifiable numbers or definitions. Such uses imply a broad range of conditions or behaviors grouped together and studied under a single title for ease of discussion.”

We use spectrum because it’s easier to do so and because we don’t have 100 different, perfectly defined types of Autism in the spectrum. We don’t have: “Jimmy Jones presents with ADS#72” and even if we did, it would probably look more like, “Jimmy Jones presents with ADS72 with non-specific characteristics of ADS34 and a dash of ADS9.” We are limited in that we have a spectrum, an umbrella of sorts with perhaps more dissimilarities than similarities between those on it but it’s the umbrella we have so let’s use it because it allows us to move forward on the discourse.

As for the term treat   and what I “mean” by it, now we are getting into strictly defined   terms.  Treat means:
1. To give medical aid to someone.
2. To give medical aid to counteract a disease or   condition.

Treat does not mean cure. .  Likewise, recovery does not mean remission. Asymptomatic does not mean therapeutic benefit.  A treatment, when applied to different people with the same condition or different people on a spectrum, may result in dissimilar responses or results. Some may recover, some may become asymptomatic, some may derive significant therapeutic benefit, some may derive lesser benefits and some may have no significant response to a treatment and some may have limited quantifiable change yet huge quality of life improvement.  I wish there were guarantees on treatments but there are not.

In addition, there are many different kinds of treatments stemming from different schools of thought on cause, affect, symptom alleviation, etc.  There is HBOC, MSC, Chelation Therapy, Nutritional Intervention, Gut Bacteria Proliferation, etc. and many studies showing their safety and efficacy and many swear by them.  Some of these treatments or therapies or interventions have worked for some on the spectrum and because it’s a spectrum, may not work on others. But we educate ourselves to what’s available and the new studies and advancements.

So, here are a few articles. Some will be relevant to your inquiries, some will not. I hope they are helpful and enlightening.  And this is not the sum total of the information out there, just a broad brush stroke collection.   I’ll keep looking and I’ll try to gather some more over the next few days to create a more comprehensive… spectrum…of data and information:  AUTISM AND STEM CELL TREATMENTS

———————————————————————-

I’ll leave you with this one last thought.  I used the image at the top for a reason.  It is something I’ve been wrestling with quite a lot lately.  Is Autism an identity or a disability?  Should we search for a cure or try to understand it.  I wrote an article on the subject early this month – AUTISM: IDENTITY OR DISABILITY  

And a chicken and the egg scenario just occurred to me.  Simply put:

Stem cells are the body’s natural healing system.  If you implant stem cells into the body, it will begin to repair itself.  It is the job of the stem cell to assist your body in functioning as well as it possibly can.  Dead tissue can begin to regenerate, new tissue can begin to develop, genetic anomalies can begin to correct, etc.  The stem cells and the body “know” what needs to be done or even, what needs to be fixed.  We can force them to do ‘x’ but eventually they will go fix ‘y.’

So if stem cells ‘fix’ something, that means (at the very least) that the stem cells and your body believed it needed ‘fixing.’  So in the simplest of terms and the broadest of definitions, if stem cells fix Autism, was it not because it needed to be fixed?  I don’t know.  I’m asking.  Maybe you have a different view.  If you do, I’d love to hear it.

p.s. A “friend” noted that cure is perhaps not the best term to use and I agree.  We do need a new set of words. Both for that reason and because we need to start seeing people as people and not as patients and definitely not as diseases. 

Further, when I eat well it is not to cure, when I go to the gym it is not to cure, when I meditate or do yoga it is not to cure. All of these things are to maximize my life, my health, my soundness of body and mind, my time on this earth, not to cure. Part of the issue is that Western medicine treats illnesses not people…wait until someone is sick and then try to fix what’s wrong with them with zero ‘cures’ since Polio 1954.   A pretty backward way of thinking.  Eastern medicine prevents disease as a by product of the efforts taken to maximize one’s health, vitality and life. We could learn a lot from this attitude.

PARENTS WHO WILL STOP AT NOTHING TO HEAL THEIR OWN

In ALL ARTICLES, OFF THE BEATEN PATH on April 24, 2013 at 11:00 am

Dedicated to the amazing women (and men) who are doing everything in their power to heal their children…

Do not confuse them for a distracted and solitary parent sitting alone in a dark corner on a laptop, sipping a spritzer and dangling a toe into stem cell treatments.

These are parents who are researching for years, they network and talk to everyone they can get their hands on, they create pages and sites and media campaigns, they compare data with each other and they do it better than a super computer, more relentlessly than a pit-bull and they do not give up and do not surrender.

They are intense and even fanatical researchers with passion, drive, motivation, education and intelligence and they are going to change the entire stem cell industry from the inside out.  You can love them or hate them but do NOT get in their way.  They are blind to bureaucracy, oblivious to obstacles and dismissive of despair.  Their engines run on the nova hot burning jet fuel of a parent’s love for their child, they wield weapons built on research and science and wear impervious suits of armor forged in hope.

They are stem cell moms and they are organized and aggressive and nothing will stand in their way.

They are…

THE STEM CELL MOMFIA

wgun4

AUTISM: IDENTITY OR DISABILITY?

In ALL ARTICLES, OFF THE BEATEN PATH on April 3, 2013 at 1:03 am

autistic child
If your child had Autism, would you want him to get treated or do you think that would change “who they are.”

Change who they are?  We all change who we are every moment of every day because that is our nature.  We are the sum total of all of our characteristics, good, bad and indifferent, our experiences, the people we meet in life and what we learn.  Given different circumstances, war, peace, hunger, satiety, illness, wellness, depression, happiness, love, hate, we are constantly changing.

There are many cultures who make meals with 5 tastes so they experience all there is to experience in every meal.  Experience is good.  And  I don’t think children are defined by an illness any more than they are defined by a capability.  Sure, your child is your Autistic child but do you define them that way?  “Hi, I’m Jane and this is my Autistic child Bobby.”  Maybe you do.  Maybe that helps pre-explain some behavioral idiosyncrasies.  But on a deeper level, isn’t your Autistic child “just” your child just as your child the doctor is fundamentally “just” your child.  If he loses his job or gets a divorce and comes crying to mommy, isn’t he “just your child.”  I think a child who’s got a condition or whose leg is amputated will continue to adapt and change just as a child who’s an elite runner or a protege pianist will continue to adapt and change.  It is not our illnesses or gifts that define us, nor is it what happens to us that defines us nor even what we are that defines us.  We are defined by how we deal with life, with adversity, with others and with ourselves.

All humans are dynamic and changing.  We learn, we grow, we evolve, we mature.  There is no single snap shot in life and to hold onto one identity is unhealthy, it would seem to me.  Like holding onto a snap shot of a child and remembering them only in that moment…even after they have grown past that moment and that point in their life.  I think we should all embrace change, growth and evolution.  I think we should all hope for more or hope for different, always, for all of us… because without it we are talking about a static existence.  And I believe that when we stop evolving, we start dying.

This argument goes on in the deaf community too.  I made the mistake of once, a long time ago, assuming everyone would want their deaf child healed.  Boy did I get an earful (no pun intended).  Many parents of deaf children, especially if the parents are deaf themselves, don’t want the child to lose the deaf culture.  But I wonder…does a deaf child who gains or regains their hearing suddenly forget sign language? DO they lose the ability to appreciate silence?  Or do they gain something and add it to their experiences, to who they are, to their identity?

I studied architecture and now I work in stem cells.  Have I lost what it means to be an architect?  Shall I excise it from my life and my resume?  Or did that help pave my path and will color my life for the rest of my life?

There’s a great story about how Steve Jobs dropped out of Stanford and in dropping out of the required courses, he was able to drop in on what interested him, like Calligraphy. That course then went on to define the fonts used in all Macs and then all PCs and all computing.  He took the computer science knowledge and added it to his calligraphy knowledge and many other experiences and all of it came together to define him and his work in unexpected ways…the whole is greater than the sum, of the parts.

Likewise, I do medical communications, writing, marketing…but I can’t help but look at buildings in a certain way, I think about space and light and movement.  I still design for friends and neighbors.  I can’t, not be an architect.  It’s part of me, it won’t go away.

I recently spent 4 hours in the Houston airport discussing the corporate design process with an ICloud designer and organization infrastructure guru but…he didn’t talk like a tech guy…he talked like an architect.  Turns out, like me, he had 2 degrees in architecture and like me, it colored everything he did in life and work.

I don’t think I’m the best architect in the world or even as good as I could be if I practiced my craft every day and I’m certainly not up to date on some of the codes and software but those experiences, that way of looking at the world and thinking and processing information, will never go away and I will never be able to define who I am without them.  One thing doesn’t replace another; it is all accumulative.

I don’t know.  Maybe that has no bearing on a child with Autism.  I probably would have to walk a mile (or run a marathon) in their or your shoes.  I’m just on the outside looking in.  But I’m willing to listen and learn because, after all, I’m always evolving, always changing.

Baby monkeys given standard doses of popular vaccines develop autism symptoms

In ALL ARTICLES, OFF THE BEATEN PATH on January 17, 2013 at 10:23 pm

monkey-vaccines-autismautistic child
Vaccines In University of Pittsburgh Vaccine Study

Apr 29th, 2012 | By | Category: Catherine Frompovich, Recent Articles, Recent Articles, Top Stories

A University of Pittsburgh study showed vaccines altered the behavior in monkeys.

Someone did perform safety studies the U.S. Centers for Disease Control and Prevention (CDC) and the U.S. Food and Drug Administration (FDA) should have mandated be performed and vetted BEFORE numerous vaccines were released into the public sector for mass vaccinations.

Lead investigator Laura Hewitson, PhD, probably dropped a bombshell when she and her colleagues completed a macaque monkey (primates) study of the very same vaccines given to children during 1994-1999, i.e., the Measles-Mumps-Rubella (MMR) vaccine and several Thimerosal mercury-containing vaccines injected into children during that time frame when the autism spectrum disorder skyrocketed.

The results of that pilot study were published as a Research Paper in Acta Neurobiological Experimentals in 2010 and titled “Influence of pediatric vaccines on amydgala growth and opioid ligand binding in rhesus macaque infants: A pilot study.”

TO SEE THE ORIGINAL STUDY:  Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study   http://www.ane.pl/pdf/7020.pdf

[1] Even though there was alleged controversy revolving around Hewitson’s monkey studies, e.g., charges of conflicts of interest since she filed a claim with the vaccine court on behalf of her child, [2] the information generated needs to be revisited and duplicate studies need to be undertaken. Why haven’t they?  Is there too much influence from vaccine makers not to do them? Parents need to make demands on the U.S. Congress to require such safety studies on monkeys be duplicated immediately, plus suspend all mandates on vaccinations until the study results are in.  Did Dr Hewitson become another professional persona non-grata because she may have been on the right track?

Congress needs to consider seriously the Hewitson, et al. report that stated:

“Vaccine-exposed and saline-injected control infants [monkeys] underwent MRI and PET imaging at approximately 4 and 6 months of age, representing two specific timeframes within the vaccination schedule. …

“These results suggest that maturational changes in amygdala volume and the binding capacity of [11C]DPN in the amygdala was significantly altered in infant macaques receiving the vaccine schedule.” [1]

That alone should be the explicit reason for duplicating the monkey study with independent non-pharmaceutical industry conflict of interest scientists.

In this author’s opinion, no one has bigger conflicts of interest in study outcomes than the pharmaceutical makers who routinely perform them.  Those are the very studies that should be subject to the same criticism as Dr Hewitson’s.  Why aren’t they?  Good question?

For those keeping track data, ASD went from 1 in 5,000 in the 1990s to the recently acknowledged [March 2012] figures of 1 in 88 along with 1 in 6 children in the USA having developmental disabilities.  These stats were generated for data in the years 2006 to 2008. [3] There’s a 4 to 6 year lag time.  Could ASD be 1 in 50 by now at the rate it is escalating?, especially since there’s a heavier push on mandates for vaccinations.

According to the Hewitson, et al. research study, biological changes and altered behaviors did occur in vaccinated monkeys, which resembled and were similar to those observed in ASD diagnosed children.  However, there were no such symptoms showing or present in unvaccinated monkeys.  Don’t you just gotta love those little monkeys!  Guess what else the ASD monkeys came up with, and Dr Wakefield is gonna like this one: Gastrointestinal problems manifested in vaccinated macaques such as “many significant differences in the GI tissue gene expression profiles between vaccinated and unvaccinated animals.” [3] It’s been a deeply debated topic within medicine that vaccinated children who contract ASD also have GI tract issues.  Personally, I gotta wonder how the British Medical Journal is going to deal with encrusted dried egg on its face when duplicate studies confirm the Hewitson monkey results.  Perhaps the infamous BMJ retraction of the Wakefield article and Doctor’s professional evisceration, commonly referred to as the “Wakefield Syndrome,” euphemistically speaking is medicine protecting its vested interests.

Those little monkeys, however, came up with some other significant information that led former National Institutes of Health director Dr Bernadine Healy to voice some bon mots like:

“I think public health officials have been too quick to dismiss the hypothesis as ‘irrational,’ without sufficient studies of causation…without studying the population that got sick.”

“I have not seen major studies that focus on 300 kids who got autistic symptoms within a period of a few weeks of the vaccines.” [4]

Perhaps the most on-point quote regarding the monkey study came from Scott Bono, the National Autism Association chairman, i.e., something those who are accused of being against vaccinations have been questioning and demanding:

“To date, the CDC has conducted no safety testing on the possible harmful effects of simultaneously administering multiple vaccines to infants, and has steadfastly refused to state a preference for mercury-free vaccines to be given to children and pregnant women.  It’s time for HHS and Congress to step in and take vaccine safety away from the CDC.”  [4]

This author’s retort to Mr. Bono’s remark is that vaccine safety should be taken away from the Food and Drug Administration too!  I’d like to remind readers that Congress is more at fault than anyone in this vaccine debacle.  Congress has oversight and it has dropped the ball big time, probably due to all the lobbyists from Big Pharma who prowl the halls of Congress with deep pockets and nice expensive luncheon dates.

One of the issues I feel Congress has been remiss about is that it has not demanded safety studies and interaction of multiple vaccines studies BEFORE being placed into the marketplace.  According to common and accepted knowledge, no such safety research or studies have been done on the current childhood vaccination regimen, except until the Hewitson ‘monkey business’ that was funded by independent, private money, for which everyone, I think, should be eternally grateful. However, the study had to be shot down since it was not favorable to vaccine makers.  Why isn’t someone else duplicating the monkey studies?  Are they afraid of becoming another victim of science?  Why, when isn’t that what medical science should be all about: investigating problems and theories, publishing results, and interacting with other sciences, NOT excommunication as if they were breaking some religious dogma.  Or, do they, in some vested interests minds?

Current Vaccine Safety Activism in Congress

Now here is something every VacTruth reader should consider seriously: Supporting Congressman Dan Burton’s (R-5-IN) request to the House Committee on Oversight and Government Reform Chairman Darrell Issa to hold hearings on the Vaccination Injury Compensation Program. Back on January 12, 2011, this writer filed a Whistleblower’s Complaint on Vaccines with Chairman Issa and has yet to receive an acknowledgement of that filing.

Isn’t about time to revisit, update, and do more extensive research into the Autism Spectrum Disorder pandemic that is spreading globally?

April 24, 2012 Congressman Burton posted a letter to The Hill’s Congress Blog titled, “It is time to re-engage on the autism epidemic.”  He also wants to pass legislation to force the President to address the ASD epidemic and its impact on Americans.  Burton is committed to helping millions of children, adults, and families afflicted with ASD.  We need to support Congressman Burton ASAP and here’s how:

  1. Contact the Canary Party to support their Facebook pages to hold Congressional hearings and a White House Conference on Autism.  Contact News@CanaryParty.org.
  2. Contact Congressman Darrell Issa at the Oversight and Government Reform Committee at 2157 Rayburn House Office Bldg., Washington, DC 20515 or preferably telephone your request for Autism Investigation Hearings to 202-225-5074.

For those who want to know about this information, the National Autism Association (www.nationalautism.org) will be holding a rally for toxin-free immunizations in Washington, DC on June 4, 2012, titled “Green Our Vaccines,” which this author thinks is an oxymoron.  How can you green vaccines when every ingredient is toxic?  Just check out the CDC’s PinkBook Vaccine Excipient & Media Summary at http://www.cdc.gov/vaccines/pubs/pinkbook/downloads/appendices/b/excipient-table-2.pdf.

Before I leave this article, I would like VacTruth readers to know that my colleague who also writes for VacTruth, Laraine C Abbey, RN (retired) and I co-edited a 150 page monograph in January 2011 titled Vaccines & Vaccinations: The Need for Congressional Investigation, which you can read in full on VacTruth at http://vactruth.com/vaccines-vaccinations-the-need-for-congressional-investigation/.

Apparently others have read it and agree.

Congressman Burton, Nurse Abbey and I congratulate you on taking the stand you have, and we offer you our resources in obtaining a Congressional investigation.

President Obama, Nurse Abbey and I respectfully request a White House conference on Autism, and we offer you our resources to effectuate a non-biased conference.

VacTruth readers, I charge you with spreading this information and article as far and wide as you possibly can so that we can get an investigation that ought to be open, not biased, and the scientific facts—nothing but the facts, like those the monkeys finally had to prove.  It was not monkey business; it’s the real deal.

via http://vactruth.com/2012/04/29/monkeys-get-autism/

References:

[1] http://www.ane.pl/pdf/7020.pdf

[2] http://leftbrainrightbrain.co.uk/2010/07/laura-hewitson-has-left-the-university-of-pittsburgh/

[3] http://www.cdc.gov/ncbddd/autism/data.html

[4] http://www.vaccineriskawareness.com/Infant-Vaccines-Produce-Autism-Symptoms-In-Primates

AND BY THE WAY…

Court Awards $969,474.91 for MMR Vaccine Causing Boy’s Autism

http://vactruth.com/2013/01/18/mmr-vaccine-causing-autism/

STEM CELLS, AUTISM and stuff

In STEM CELLS IN THE NEWS on August 29, 2012 at 3:48 pm

https://i1.wp.com/www.nh-di.org/nh/wp-content/uploads/2010/11/clarifications290.jpg

First a disclaimer.  I am a stem cell writer/author/advocate.  While you may think this means I have an agenda (I do, to help patients get better), I am very careful to site real data sources for my info.  My “opinions” are based on science.  [For example, I am uninterested in embryonic stem cells because they will not produce treatments for decades, they cause cysts and tumors and they require immunosuppressive drugs.]

Many of my sources are from my own blog so if you find this too self-referential or if you find any data lacking on a specific subject, please ask and I will tell you where I got my original data from.  Please feel free to comment on my blog.  It is an open forum on the benefits of adult stem cell treatments.  I welcome all intelligent and rational communication and my site is not monetized so I make no money if you go there, comment or otherwise.

Ok, there’s a lot of misinformation out there. Let’s clear it up.

ADULT STEM CELLS or ASC – https://repairstemcell.wordpress.com/stem-cells-for-newbies/
SOURCE/DERIVED FROM•comes from blood, umbilical cords, bone marrow, placenta fat tissue, muscle, nasal neurological, breast milk, menstruation, dental pulp, lungs, eyes, brain and many more
PURPOSE IN BODY•they are the body’s natural healing cells
OBSTACLES+SIDE EFFECTS•virtually zero side negative effects, many positive side effects
TREATMENT HISTORY•used in bone marrow transplants to treat cancer for 40 years, can currently treat 130+ diseases safely and effectively (CP, MS, Autism, Diabetes, CHF, PAD, etc)

For example, blood derived stem cells are a very valid source of stem cells and many treatment centers and clinical trials using blood derived stem cells for years with extremely positive results.  The first stem cell treatment center in the world generated significant therapeutic benefit for over 62% of their congestive heart failure patients.  These are called no option CHF patients because their only recourse is a heart transplant.  62% of “no option” CHF patients derived significant therapuetic benefit, sometimes doubling their Ejection Fractions (amount of blood pumped out by the heart).  But this is anecdotal, let’s talk data.

What data is their showing that stem cell treatments work?
Anecdotal and 10’s of thousands of patients treated aside…as of late 2009, according to the National Institutes of Health, there were and are ~2600 stem cell clinical trials around the world – http://www.clinicaltrials.gov/
Of those ~2600, there are ~2591 mentions of adult stem cells.
Of those ~2591, about half of them (~1300) are actual adult stem cell clinical trials.

Currently, as of today, there are 3,989 clinical trials under keyword search “stem cell” illustrating the safety and efficacy of utilizing stem cells to treat chronic and terminal diseases. Many are from reputable colleges and hospitals around the world, some in the US like Duke U., Northwestern, etc.

How about for Autism? (I apologize, my data has not kept current but as of late 2009)
https://repairstemcell.wordpress.com/2009/10/26/stem-cells-for-autism/
and https://repairstemcell.wordpress.com/2009/10/16/potential-of-stem-cell-treatments-for-autism/

Please also look at the 29,500 scholarly papers submitted on “stem cell” plus “autism” minus embryonic.  These are up to date:
http://scholar.google.com/scholar?as_q=autism&as_epq=stem+cell&as_oq=&as_eq=embryonic&as_occt=any&as_sauthors=&as_publication=&as_ylo=&as_yhi=&btnG=&hl=en&as_sdt=1%2C39&as_vis=1

I hope this was informative. If I can be of any assistance on specific diseases or questions, please feel free to ask.

Reuters Health Report – dsgrano@gmail.com – Jan 23, 2012

In ALL ARTICLES on January 23, 2012 at 10:45 am
Korean research, a first step toward Dr. Smartphone?
“We have confirmed that (touch screens) are able to recognize DNA molecules with nearly 100 percent accuracy just as large, conventional medical equipment can and we believe equal results are possible for proteins,” Park told Reuters TV.“There are proteins known in the medical world like the ones used to diagnose liver cancer, and we would be able to see the liver condition of the patient…”
SEOUL (Reuters) – Tired of long waits at the hospital for medical tests? If Korean researchers have their way, your smartphone could one day eliminate that — and perhaps even tell you that you have cancer. | Full Article
U.S. consumers tell insurers to cover experimental drugs

January 23, 2012 09:42 AM ET

If stem cell treatments in the US are experimental, perhaps insurance will one day cover therm…but don’t hold your breath!

NEW YORK (Reuters) – When your health insurance provider denies an experimental treatment or a high-cost drug, how much are you willing to pay for the care you believe you need? | Full Article
Anxiety, other disorders more common in autism
January 23, 2012 02:13 AM ET
NEW YORK (Reuters Health) – Autism tends to go hand in hand with a variety of other mental and behavioral conditions in kids, suggests a new study that highlights the fuzzy nature of autism diagnoses themselves. | Full Article
Man dies of bird flu in southwest China: report
January 23, 2012 09:23 AM ET
BEIJING (Reuters) – A man in southwest China died of bird flu on Sunday after three days of intensive care treatment in hospital, the official Xinhua news agency quoted the Ministry of Health as saying. | Full Article
Fitting fitness inside the cubicle
January 23, 2012 06:29 AM ET
NEW YORK (Reuters) – Whether your office is in the business district or on the dining room table, sitting immobile for hours in front of a computer screen is at odds with the fit body. | Full Article

Reuters Health Report – dsgrano@gmail.com – Gmail.

FAKE AND FRAUDULENT SCIENCE

In DISEASE INFO on October 27, 2011 at 2:32 am

FAKE AND FRAUDULENT SCIENCE

  • Scientific empirical data is subject to misinformation and corruption as much as what some refer to as the “soccer mom hysteria.”
    For example:  Dr Thorsen’s data on the correlation between MMR vaccines and Autism is corrupt and dependent on elements outside the study both ignored and cherry picked around:

    “Thorsen was a leading member of a Danish research group that wrote several key studies supporting CDC’s claims that the MMR vaccine and mercury-laden vaccines were safe for children. Thorsen’s 2003 Danish study reported a 20-fold increase in autism in Denmark after that country banned mercury based preservatives in its vaccines. His study concluded that mercury could therefore not be the culprit behind the autism epidemic.

    His study has long been criticized as fraudulent since it failed to disclose that the increase was an artifact of new mandates requiring, for the first time, that autism cases be reported on the national registry. This new law and the opening of a clinic dedicated to autism treatment in Copenhagen accounted for the sudden rise in reported cases rather than, as Thorsen seemed to suggest, the removal of mercury from vaccines. Despite this obvious chicanery, CDC has long touted the study as the principal proof that mercury-laced vaccines are safe for infants and young children. Mainstream media, particularly the New York Times, has relied on this study as the basis for its public assurances that it is safe to inject young children with mercury — a potent neurotoxin — at concentrations hundreds of times over the U.S. safety limits.

    Thorsen, who was a psychiatrist and not a research scientist or toxicologist, parlayed that study into a long-term relationship with CDC. He built a research empire called the North Atlantic Epidemiology Alliances (NANEA) that advertised its close association with the CDC autism team, a relationship that had the agency paying Thorsen and his research staff millions of dollars to churn out research papers, many of them assuring the public on the issue of vaccine safety.

    The discovery of Thorsen’s fraud came as the result of an investigation by Aarhus University and CDC which discovered that Thorsen had falsified documents and, in violation of university rules, was accepting salaries from both the Danish university and Emory University in Atlanta — near CDC headquarters — where he led research efforts to defend the role of vaccines in causing autism and other brain disorders. Thorsen’s center has received $14.6 million from CDC since 2002.

    Thorsen’s partner Kreesten Madsen recently came under fierce criticism after damning e-mails surfaced showing Madsen in cahoots with CDC officials intent on fraudulently cherry picking facts to prove vaccine safety.

    Leading independent scientists have accused CDC of concealing the clear link between the dramatic increases in mercury-laced child vaccinations beginning in 1989 and the epidemic of autism, neurological disorders and other illnesses affecting every generation of American children since. Questions about Thorsens’s scientific integrity may finally force CDC to rethink the vaccine protocols since most of the other key pro vaccine studies cited by CDC rely on the findings of Thorsen’s research group. These include oft referenced research articles published by the Journal of the American Medical Association, the American Journal of Preventive Medicine, the American Academy of Pediatrics, the New England Journal of Medicine and others. The validity of all these studies is now in question.”

    via https://repairstemcell.wordpress.com/2010/03/15/cdc-vaccine-cover-up-mercury-actually-does-cause-autism/

mercury toxic element,Who Discovered Mercury,mercury element,toxic,tannoy f4 custom,poisoning symptoms,interesting facts about mercury,facts on the planet,outboard motors,how many moons does,how far is from the sun, insurance complaints,lithgow mercury,outboard motor parts,passenger vehicles e bay motors,manhattan mercury,who discovered the planet,pottstown mercury newspaper,mercury gemini mind games,mercury engine oil,what color is mercury,pictures of mercury,mercury grand  marquie clubs,mercury symbol,san jose mercury newspaper

 

  • PFIZER, CELEBREX, BEXTRA + VIOXX CLINICAL TRIAL RESULTS WERE FAKE- FRAUD
    February 18, 2010 at 1:55 pm “It’s being called the largest research fraud in medical history. Dr. Scott Reuben, a former member of Pfizer’s speakers’ bureau, has agreed to plead guilty to faking dozens of research studies that were published in medical journals. Now being reported across the mainstream media is the fact that Dr. Reuben accepted a $75,000 grant from Pfizer to study Celebrex in 2005. His research, which was published in a medical journal, has since been quoted by hundreds of other doctors and researchers as “proof” that Celebrex helped reduce pain during post-surgical recovery. There’s only one problem with all this: No patients were ever enrolled in the study!” https://repairstemcell.wordpress.com/2010/02/18/pfizer-celebrex-bextra-vioxx-clinical-trial-results-were-fake-fraud/


    repairstemcell.wordpress.com

    ‎”It’s being called the largest research fraud in medical history. Dr. Scott Reu…

 

  • and need I mention the Embyonic hoax perpetrated on the US populace for a decade?

    The pure and impartial and just eye of the scientist is just as susceptible to partiality as any other if not more so because they think thy can get away with it.

    The Placebo Defecthttp://naturalnews.com/030209_placebo_medical_fraud.html

    “This is the conclusion from researchers at the University of California who published their findings in the October issue of the Annals of Internal Medicine. They reviewed 167 placebo-controlled trials published in peer-reviewed medical journals in 2008 and 2009 and found that 92 percent of those trials never even described the ingredients of their placebo pills.”

    Empirical science is not a hat you take off when it is convenient. Everything has an effect and if test tubes are not sterile and compounds are contaminated and trials are screwed up then they can not be considered valid. 92%. Nuff said.

https://i2.wp.com/no92.com/assets/images/autogen/a_nO92_logo.gif

%d bloggers like this: