Posts Tagged ‘australia’


In Doctors Practicing Excellence, SCIENCE & STEM CELLS, STEM CELLS IN THE NEWS on January 27, 2017 at 1:50 pm

Biomedical scientist Alan Mackay-Sim is one of the pioneers in stem cell research, digging into (pun intended) the enormously productive (flowing?) area of “olfactoric mucosal stem cells” or neurological stem cells from inside your nose responsible for your sense of smell.

  1. Lu, J.; Feron, F.; Ho, S. H.; Mackay-Sim, A.; Waite, P. M. E. Transplantation of nasal olfactory tissue promotes partial recovery in paraplegic adult rats. Brain Research 2001, 889, 344-357.
  2. Lu, J.; Feron, F.; Mackay-Sim, A.; Waite, P. M. E. Olfactory ensheathing cells promote locomotor recovery after delayed transplantation into transected spinal cord. Brain 2002, 125, 14-21.


Alan Mackay-Sim, the scientist whose miracle made a paraplegic walk again, named Australian of the Year

JANUARY 25 2017 – Biomedical scientist Alan Mackay-Sim, whose research helped achieve a feat described as “more impressive than man walking on the moon”, has been named the 2017 Australian of the Year for his pioneering stem cell research.

Professor Mackay-Sim’s work was central to the 2014 surgery that allowed Darek Fidyka, a Polish firefighter, to walk again and even ride a custom-built bicycle. This made him the first (well, not the first but no less significant) paraplegic in the world to recover mobility after the complete severing of the spinal nerves. The success was hailed by fellow researcher Geoff Raisman as more impressive than the moon landing.

Professor Mackay-Sim is a leading global authority on the human sense of smell and the biology of nasal cells. The successful surgery that allowed Mr Fidyka to walk again involved taking cells from his nose, growing them in a lab and injecting them into his spinal cord.

Prime Minister Malcolm Turnbull gives Alan Mackay-Sim his honour.

Professor Mackay-Sim, 65, himself relied on a stem cell transplant two years ago when he was diagnosed with myeloma, a rare form of blood cancer that develops in the bone marrow.

He was presented with his Australian of the Year award by Prime Minister Malcolm Turnbull on Wednesday night…


A history of stem cell treatments for spinal cord injury




Stem cell treatment for spine tested

An Australian-invented stem cell treatment for spinal surgery has been successfully used for the first time in the United States.  The patented stem cells product created by Melbourne-based company Mesoblast was trialed in a small group of patients with spinal discs that had degenerated beyond repair.  The bone marrow-derived stem cells – called mesenchymal precursor cells (MPCs) – were used to promote bone growth to fuse together spinal vertebrae, to eliminate debilitating leg and back pain.

If the procedure ultimately passes the final stage of clinical trials and is approved by America’s drug regulator, it would potentially provide patients worldwide with a quicker and less invasive procedure.

The Food and Drug Administration (FDA)-approved trial compared the use of stem cells to fuse vertebrae with bone harvested from the patient’s own hip, the current gold standard for this common operation.  The stem cells were used in conjunction with two chemicals to encourage bone growth, said Texas surgeon Dr Randall Dryer, who performed a number of surgical procedures in the trial.  The chemicals, hydroxyapatite and tricalcium phosphate, are non-cellular components of bone that tell the stem cells to turn into bone-forming cells, rather than other tissues, “If you put these cells into an environment that stimulates them to grow into bone, they do.  That eliminates us having to take the patient’s own bone from a different location to pack in there“, said Dr. Dryer, an orthopedic surgeon at the Central Texas Institute in Austin.

Eight of the 24 patients enrolled in the trial had the surgery using their own bone.  Of these, six patients’ bone had successfully fused after a year.  Six out of seven patients given a low concentration of stem cells had equally successful results, while five out of eight patients given a higher concentration of stem cells achieved the bone fusion.  “These stem cells work at least as good as or better than the patients’ own bone.”  The advantage of the operation is that it cancels the need to harvest the patient’s own bone, which lengthens the surgery time, is more painful and can lead to more complications.  This is hopefully going to be a new tool that we can use to help patients recover less painfully, quicker and with just the same effectiveness.” There were no adverse events in the phase two trial, which tests the product for safety and efficacy.  The company plans to apply for FDA approval to conduct a larger phase three trial in the United States, Europe and Australia later this year.


Related articles

New Disease Identified By Australian Researchers

In VICTORIES & SUCCESS STORIES on May 27, 2010 at 9:40 am

And now, stem cells are treating disease that we don’t even know about yet! – dg

New Disease Identified By Australian Researchers

Researchers at the Queensland Institute of Medical Research (QIMR) and the Royal Brisbane Women’s Hospital have identified a previously undiagnosed condition and successfully treated it by performing an experimental stem cell transplant.

Having spent her late teenage years in and out of hospital Katie Pulling had almost given up hope. “It was very confusing and very daunting. I kept hearing the doctors say, ‘We don’t know what is wrong’, ‘We don’t know why you are so sick’,” said Katie, who lives in north-eastern NSW.

With no options left Katie agreed to an experimental stem cell transplant – a transplant which ultimately saved her life.

“Katie presented with a range of symptoms when she was eleven. No one could identify her condition and no treatment had been successful. She did not respond to regular treatments and she continued to get sick, often complicated by life-threatening infections,” said Dr Maher Gandhi head of QIMR’s Clinical Immunohaemotology Laboratory.

The key to unlocking the reason for Katie’s reoccurring symptoms came when she contracted the common teenage virus that causes glandular fever. Usually most people come down with only a mild infection. However, Katie developed a full-blown version known as fulminant infectious mononucleosis (FIM)…

via New Disease Identified By Australian Researchers.

Charlestown boy’s sight improves after stem cell treatment

In VICTORIES & SUCCESS STORIES on May 25, 2010 at 10:00 am

IMPROVEMENT: Connor Wink, 11, and his mother Tracey.

Charlestown boy’s sight improves after stem cell treatment

BY DONNA SHARPE – 18 May, 2010 10:44 AM

A CHARLESTOWN boy is showing marked signs of improvement in sight after his first round of stem cell treatment.

Connor Wink, 11, and his mother Tracey recently returned from China where he received a round of injections, which are not available in Australia.

The treatment appears to have had dramatic results.

Connor has gained light perception, a sign the treatment is working.

Born blind, he also suffers nystagmus, a condition which means Connor has poor muscle control causing his eyes to move frequently.

“That has slowed right down so it’s certainly a big plus,” Mrs Wink said.

Connor is the second Hunter child to undergo stem cell treatment in China.

Holly Arvidson, 12, of Denman, is having a second round of the procedure in a bid to restore her sight.

For the past 12 months, The Herald has been following the progress of Holly, who is in China with her family for the treatment which involves stem cell injections, acupuncture and bone marrow cultivation.

The treatment is only available in a handful of hospitals worldwide. It has an 80 per cent success rate but since Holly’s first round her condition has not changed.

Mrs Wink said she is praying Holly receives a positive result this time.

“Connor was lucky and we have seen improvements. We were sitting in front of a fire at the weekend and he could tell when someone was putting logs on it,” she said.

The Charlestown community and Connor’s school, Hillsborough Public, helped raise money for the China trip.

“We still have enough money to travel for Connor’s second round of treatment thanks to those earlier fund-raising efforts which Connor was a big part of, raising $6000 busking.”

via Charlestown boy’s sight improves after stem cell treatment – Local News – News – General – The Herald.

New Stem Cell Therapy For Dogs Launched In NZ | Voxy.co.nz

In VICTORIES & SUCCESS STORIES on April 26, 2010 at 7:29 pm

Tuesday, 27 April, 2010 – 10:22

A breakthrough stem cell therapy is being launched in New Zealand – offering a new lease on life for dogs suffering from degenerative joint disease.

New Zealand’s largest companion animal veterinary group, Pet Doctors, has announced a national license agreement to treat dogs with a stem cell technology called AdiCellTM.

Pet Doctors has partnered with Regeneus Pty Ltd, a Sydney-based pioneering biotech company, to distribute AdicellTM here. New Zealand will be only the third country in the world, following the US and Australia, to offer this type of therapy commercially…

via New Stem Cell Therapy For Dogs Launched In NZ | Voxy.co.nz.

$1.5 million for ADULT stem cell research in Australia

In BUSINESS OF STEM CELLS on March 10, 2010 at 11:52 pm
Don’t miss any important stem cell news! Follow me on twitter! http://twitter.com/stemcellblogger
“Australian Government’s endorsement and its support for the development of adult stem cells as novel therapeutic strategies in patients.”


$1.5 million for adult stem cell research in Australia

Publciado por toddlersavoid – 10/03/10 a las 05:03:13 pm

https://i2.wp.com/medical-job-australia.com/img/medical-australia.jpgAustralian grown-up flow cell company, Mesoblast Limited, today announced that its chief scientific advisor and founder, Professor Silviu Itescu, has been awarded a $1.5 million grant for pre-clinical and clinical unfolding of mesenchymal harp on full-grown stem cells.  The grant was awarded under the prestigious National Health and Medical Research Council’s Program Grants Scheme, with the $1.5 million allocation being made under a specific Memorandum of Understanding.

Professor Itescu said he was delighted with the Australian Government’s endorsement and its support for the development of adult stem cells as novel therapeutic strategies in patients.“The grant will be instrumental in sponsoring a number of clinical and preclinical studies using mesenchymal lineage adult stem cells�, he said.“

There is enormous interest within the international medical community in the potential of adult stem cells to provide effective treatments for a broad range of human diseases and conditions and to vastly improve the quality of life for many people.

“Additionally, these therapies may result in significant reductions to ballooning health care costs�, Professor Itescu said.The Chairman of Mesoblast, Mr Michael Spooner, indicated that subject to material transfer agreements, Mesoblast would make available its specialist Mesenchymal Precursor Cells for these and other Government and industrysponsored studies.http://www.mesoblast.com

Cardiomyopathy Patient Can Do Triathlon After Adult Stem Cells

In VICTORIES & SUCCESS STORIES on March 8, 2010 at 9:00 pm

Don’t miss any important stem cell news! Follow me on twitter! http://twitter.com/stemcellblogger

Eighteen months in the life of Jason Ludwick has been dominated by what he could do. He was in and out of hospital and living with a cocktail of expensive drugs to try to keep your heart failing operation. Then, like hundreds of others went to Thailand for adult stem cell therapy for real help heart disease.

Jason Ludwick aged 34 from West Bloomfield, Michigan, counts himself a lucky man. Born with an atrial septal defect, when I was 15 had a pacemaker, 21, was diagnosed as having cardiomyopathy and 25 had a defibrillator in place and an ejection fraction only 8-10 percent. Heart failure dominated and restricted his life until he received adult stem cell therapy. Now he says that with the training I could do a triathlon.

While his teammates ran and played sports, Jason’s life has been dominated by his illness and his heart does not guarantee which does not run and do not practice any contact sport. I was in and out of hospital and living in a cocktail of expensive drugs. Bled your kidneys, your inflammation the liver, which suffered from asthma and had trouble getting rid of a common cold. Still, Jason has tried to live as normally as possible, though her heart was failing constantly.

His mother called for help after being removed from a heart transplant list. It was then left alone with drugs, I had some unpleasant side effects, and always felt tired and depressed, as he paced back and forth to specialists with their medication reviewed. And then his mother know about therapy with adult stem cells.

Barely a month after gene therapy for adult cells, Jason knows that his life would change, “My heart was beating better, more rhythmic, and I had more energy,” he said. “After six months, I got up and flying, feeling 100 percent different. I could mow the lawn, walking, bicycling with my kids, lift weights – do whatever I wanted, “he said.” I’m always on the road with our fifth child on the road and still working as full-time mother. ”

Jason has always enjoyed a tremendous level of support from family and friends, but is very happy to spend time advising other cardiomyopathy people the power of positive thinking. “We always try to be positive,” he advises. ” There is hope. Watch your diet and get the word adult stem cell therapy is interesting to do. This is nothing like what you might think. ”

Hundreds of people suffering from terminal to terminal failure of the heart, cardiomyopathy or coronary disease, who were impressed by the result of adult stem cells and clinical outcome. Those who said they are without any treatment option now have the option of staying home to await death or to join more than 75 percent which has a life characterized by greater energy and less symptoms.

The adult stem cell therapy, which appears to be a lifeline to all Heart patients who are tired of being sick, or do not want their lives are characterized by restricted activity, low energy, pain, cost and brevity. The trend will continue to grow as people become more aware of that can not be harmed by a therapy that uses their own adult stem cells and that the procedures are simple, effective and performed in world class hospitals by skilled, heart specialists often prominent. Most encouraging clinical outcomes are compatible with the results of research and relationship with patients. If Jason gets the time to train and not a triathlon, the world just sit and take notes.


About the Author:

Jon Bradshaw writes constantly about the next to miraculous effects of adult stem cells. Theravitae’s Vescell adult stem cells the new frontier of regenerative medicine. They offer a return to a more active, longer and healthier life to patients who have heart disease or PAD. They are derived from the patient’s own blood so cannot be rejected by the body.

Article Source: ArticlesBase.comCardiomyopathy Patient Declares He Could Do A Triathlon After Adult Stem Cell Treatment

New Heart, New Love, New Son Courtesy of Adult Stem Cells

In VICTORIES & SUCCESS STORIES on March 8, 2010 at 3:50 pm
Don’t miss any important stem cell news! Follow me on twitter! http://twitter.com/stemcellblogger
New Heart, New Love, New Son Courtesy of Adult Stem Cells

Ten years ago a Surfers Paradise manss life was dominated by heart disease and time was running out. Now he has been granted a new wife and baby son better health total happiness.

Peter Irwin from Surfers Paradise in Queensland, Australia, has much to be thankful for. Ten years ago he was depressed, ill and deeply unhappy. He suffered from both Dilated Cardiomyopathy and some Ischemic Heart Disease that was slowly but surely killing him. Told there was nothing more that could be done for him and with no hope of living beyond another two years he started to seek for someone or something that could give him better odds.

An internet search unearthed that adult stem cells can offer hope and help. Peter failed to get on to a clinical trial in his own country because he was too ill to meet their entry criteria and so he went to Bangkok in October 2005 thinking he had nothing to lose.

Within four months of a simple procedure at a Bangkok Heart Hospital Peter was feeling much better and far more optimistic. His cardiologist had to agree that on clinical tests his heart was performing far more efficiently. His life since then has continued to improve. He still has some health issues but they no longer dominate his life. The greatest improvement has been that he can enjoy a far better quality of life and has high expectations of a very positive future.

Adult stem cell therapy helped his heart strengthen, revascularize and repair and he made other dietary and lifestyle changes that he thinks have also benefited him. If you are beyond hope of treatment because of heart disease, all is not lost, he said. Almost every day research is being published that shows just how many seriously ill heart patients can be returned to a life they thought they had lost.

To cap off all his gains Peter and his new wife have just recently brought into the world a new son. “Stem cells made me reconsider my life. I now have the love and care of a new partner and a son whom I love more than I thought it possible to love. It is indeed a miracle and I am so grateful”, Peter said.

Looking at the family photographs he sent at the time of his son’s birth Peter looks the picture of health and happiness. One would never know that such a short time ago he faced a brief, painful, anxious, hopeless and debilitating future.

Jon Bradshaw writes constantly about the next to miraculous effects of adult stem cells. Theravitae’s Vescell adult stem cells the new frontier of regenerative medicine. They offer a return to a more active, longer and healthier life to patients who have heart disease or PAD. They are derived from the patient’s own blood so cannot be rejected by the body.

China surpasses Canada in stem cell advances: report

In VICTORIES & SUCCESS STORIES on January 8, 2010 at 3:04 am

China surpasses Canada in stem cell advances: report

Margaret Munro, Canwest News Service Published: Thursday, January 07, 2010

Stem cells that were extracted from cow bone marrow is cultured in petri dishes J.P. Moczulski for National Post Stem cells that were extracted from cow bone marrow is cultured in petri dishes

China is seen as a wild frontier when it comes to unproven stem cell treatments, but a new report says it has surpassed Canada with legitimate and dramatic advances in the field.

Scientists in China, many of them trained at North American and European universities, published 1,116 articles on stem cells in international peer-reviewed journals in 2008, up from just 37 papers in 2000, says a team at the University of Toronto documenting China’s aggressive bid to become a major player in regenerative medicine.

China has now surpassed Canada and Australia to become the world’s fifth most prolific contributor to the exploding field that promises repair for ailing organs and tissues, the report says.

via China surpasses Canada in stem cell advances: report.


In ALL ARTICLES on November 23, 2009 at 1:05 pm

THIS article is full of so many holes, inconsistencies, half truths, biases and misinformation that it is difficult to even critique it. My comments in blue…

The author  does not make any differentiation between adult/repair stem cells (RSC) and embryonic stem cells (ESC).  Why?  Since he neglected to do this, here are the simple differences between adult/repair stem cells and embryonic stem cells:

RSC = Repair Stem Cells (same as ASC/adult stem cell but a more appropriate name)
•used in bone marrow transplants for 40 years
•can currently treat 100+ diseases
•~zero problems (virtually zero side effects)
•comes from blood, umbilical cords, marrow, fat, nose, breast milk, menstruation, etc etc etc

ESC = embryonic stem cell
•can currently treat zero diseases
•lotsa problems (tumors, rejection, controversy, etc)
•comes from embryos

Now to the article (warning on lies from Australian newspaper)

Warning on cancer risk from stem cell therapy – NICK MILLER, November 23, 2009

EXPERTS fear that a Victorian man with leukaemia may be the first Australian ”infected” with cancer after treatment at a private overseas stem cell therapy centre.

Experts?  Who are the experts? You mention “Stem cell specialists and patient support groups” but you give no credentials.  In fact, the only credentials you list are from the Embryonic stem cell doctor – Dr Kirsten Herbert and as far as I can tell, she did not even comment on this story, although she “plans next month to investigate the case.”  So she hasn’t even investigated the patient’s condition?

Experts don’t “fear”; they assess, research, deduce, investigate and make clinical and scientific observations. They pride themselves on their impartiality and emotionless scientific evaluatory skills.  To say they fear goes agianst the very core of being a scientist.  To say they fear is merely sensationalistic.

Did he go for Leukemia treatment?  Leukemia has been treated with bone marrow transplants utilizing adult/repair stem cells (RSC) for over 40 years without negative side effects. All of a sudden there is a cancer risk? Why?  Did they use embryonic stem cells in a leukemia bone marrow transplant? That would explain it…or did he get leukemia from a stem cell treatment for another disease?  What disease?  There is so little real info here in the opening line it is hard to judge what is really going on.

Stem cell specialists and patient support groups are calling for more public education about the dangers of such services, saying they get hundreds of calls a year from people considering using them – and the numbers are rising.

The companies advertise on the internet and via local information sessions, offering injections of foetal stem cells…

Foetal stem cells are essentially embryonic stem cells.  Embryonic stem cells develop into cysts and tumors.  This procedure has a history of tumors development when used.

…and stem cells extracted from the patient’s spinal cord. They claim to treat conditions such as Alzheimer’s, multiple sclerosis, diabetes, autism and spinal injury.

Private, largely unregulated clinics in Asia and Europe…

Many of them are regulated by oversight groups and standards from 3rd parties.

…charge tens of thousands of dollars plus travel costs.

Please find me one doctor or hospital in the world that pays for your travel costs.

However few have published, clinical proof of their efficacy, relying instead on slick websites and individual testimonies.

Many of them have published studies and trials.  The ONE treatment center this article focuses on does not (is the treatment center ever mentioned or is this just an attempt to paint all of the treatment centers in a bad light because of one?). As for the other qualified and reviewed treatment centers…

Costs for the majority of stem cell treatments range from US$15,000 to $35,000 including hotel but not airfare and food.


• You can get simple intravenous stem cell implants in some countries for as little as US$5000. Even if they are your own stem cells, this means in most instances that the cells are not separated and cultured from their parent tissue or fluid, which costs time and money; so we would not expect the therapy to be as effective for that reason.

You can go to a treatment center that provides inexpensive and lower quality treatments and pay the inexpensive costs…or you can go to a treatment facility that provides the best treatments and pay a higher cost…but you can NOT go to a crappy treatment center and complain about crappy treatments or get the best treatments in the world and complain about appropriate higher costs.

• It also means that the stem cells will not be implanted into a specific area based on the disease; i.e. into the heart for cardiovascular diseases, or into the pancreas for diabetes, or into the spinal canal for neurological diseases such as MS, CP, ALS and Autism.

• Some stem cells cost over US$10,000 to prepare. Some implant procedures cost over US$15,000 to perform. Some clinics include days or even weeks of physical therapy and care, which costs extra.

• In some cases expensive medical devices must be brought in to implant the cells into difficult areas such as the brain or the heart or the lungs, often doubling the cost from the above-mentioned range.

You get what you pay for, the choice is yours!

The stem cell treatments ranged in quality and safety but very few, if any, offered genuine hope, said Dr Kirsten Herbert, a hematologist at the Peter MacCallum Cancer Centre and clinical adviser to the Australian Stem Cell Centre (ASCC).

Australia, like the US, is years behind the rest of the world in regard to Repair Stem Cell treatments.  In fact, up until very recently, the focus in both countries has been entirely on embryonic stem cells.

”One man in Queensland paid $40,000 for a treatment [at a private German clinic] and was told he needed two or three more [visits] for a treatment that I cannot imagine, even with the most blue-sky open mind, could have helped him,” she said.

Which man? What disease, what clinic, what procedure, how many have been treated there for that disease with that procedure?  What are the success rates?  There is no info in here, just the status of her title to carry an empty and unsubstantiated and unreferenced comment. A quick search brought up this info from another article.  I believe this is the article she was quoted out of context from:

“From what Dr Herbert’s read about Mr Tomasiello’s case, she doesn’t understand how the course of treatment prescribed for him will work.  And among other grave concerns she has for his safety, she wants to know if the clinic is using cells that have been cultured using animal products, as that could introduce diseases such as Mad Cow.  The prospect of cells causing cancer also troubles her.  Dr Herbert denies Australia is dragging its feet in stem cell research, saying it is a world leader, and she shrugs off gasps over the use of embryonic stem cells. The creation of embryonic stem cells for scientific use is legal under federal law. All ethical dilemmas ultimately come down to an individual’s personal views, she said. And the testing that we particularly expect to see in stem cells science is what viruses could potentially have infected those cells, so HIV, Hepatitis B, Hepatitis C and some of the other related viruses. And also have those cells been tested for their capacity to form tumours?”

Of course she is worried!  Everything she is concerned about is in regard to embryonic or foetal stem cells.  Repair Stem Cell extraction has about as much negative side-effect potential as giving blood.  She is pro-embryonic stem cell research when so many in the world have abandoned embryonic research has fruitless for developing safe treatments.  She should catch up.  She is also anti-“embryonic caused problems” in the same breath.  What a very awkward position for her.

”But they will take his money and not do anything to look after him when he leaves. If we practised a treatment like that we would be disbarred.”

The top treatment centers do follow ups and make sure the patient’s GP or specialist are contacted and informed.

Dr Herbert plans next month to investigate the case of a Victorian man being treated for leukaemia, which was diagnosed after his recent return from overseas stem cell therapy.

She said it was difficult to prove a link, but there was an international precedent: in February the journal PLoS Medicine reported the case of a teenage Israeli boy who developed brain tumours from experimental stem cell injections at a Russian clinic.

Correct. He was given EMBRYONIC stem cells.  Embryonic stem cells produce tumors because their job is to split and split until they produce a fetus.  You can manipulate them to repair but when they are finished they go back to splitting and often tumors are the result.

The Israeli boy, after he got tumors from embryonic stem cells was then healed with Repair Stem Cells at one of the top treatment centers in the world.  Repair stem cells don’t produce tumors because their job is to repair and fix the tissues and organs of the body.

Dr Herbert said cancer was a rare but possible side-effect of [EMBRYONIC] experimental stem cell therapy.

There has not been a single incident of cancer from adult or repair stem cell treatments…and yet embryonic studies show cyst and tumor growth over and over.  Even the pharmaceutical giant Geron with unlimited resources and finances can’t solve this problem.

”Most stem cells grow in a culture that is exposed to proteins and hormones that encourage growth, and cancer is out-of-control growth, so these [EMBRYONIC stem] cells have a greater potential to cause cancer,” she said.

Amazing how when you drop a word or two, the entire content changes.

Other risks included contamination from animal products used in laboratory processing of the stem cells, which could introduce Creutzfeldt-Jakob disease.

Of the over 2,700 “adult stem cell” clinical trials (1,500+ complete) and 7,540 “adult stem cell” scholarly papers, evidence supports that the risk of RSC treatments are about the same as the risks associated with drawing blood.  (Standard safe practice of lab protocols removes these risks almost entirely.)

Some clinics also instructed patients to go on medication to suppress their immune systems, with potentially dangerous side-effects.

ESC treatments require the use of immunosuppressive drugs (ISD) because ESC are typically allogenic (from outside the patient’s body).  RSC are autologous (from patient’s own body) or from other sources that do NOT require ISD.  ISD are needed to offset the potential of rejection or Graft-versus-host disease (GVHD).  GVHD occurs with ESC.  Standard practice is to HLA type match the donors stem cells to the recipient’s body [“Human leukocyte antigen (HLA) typing is used to match patients and donors for bone marrow or cord blood transplants (also called BMT). HLA are proteins — or markers — found on most cells in your body. Your immune system uses these markers to recognize which cells belong in your body and which do not.”] Unfortunately, even when the ESCs are HLA type matched (both 1+2) you still need ISD because the recipient’s body can still reject the differences in many other aspects of the donated tissue.  RSC DO NOT cause rejection issues or require ISD for GVHD.

”They don’t follow these patients up,” Dr Herbert said. ”They prescribe and wave goodbye without any duty of care.”

The top treatment centers follow up with patients, the sub-standard ones don’t.  Only go to the top treatment centers.  If they do NOT follow up, they will not stay at the top for long.

The financial and emotional risks to patients were just as great, Dr Herbert said. ”Most likely, the treatment you are going to receive is not going to work.” It was important not to demonise people who sought these cures, but instead to help them find the right advice.

RSC are treating about 80% of diseases successfully and more people are discovering their benefits every day.  RSC give significant improvements to about 2/3 of the patients who are treated.

Patient advocacy groups are meeting stem cell experts in Canberra today to discuss a co-ordinated approach to public education on overseas experimental treatments.

You said this almost identical sentence above:

Advocacy groups for people targeted as possible clients will meet in Canberra today to discuss how to protect people from being emotionally and financially exploited.”

The ASCC is about to release a patient handbook to help people critically analyse stem cell treatments. It has a list of questions to ask before signing up.


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