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Archive for the ‘STEM CELLS FROM THE PAST’ Category

SCIENTISTS “STUNNED” AS STROKE PATIENT WALKS AGAIN

In ALL ARTICLES, SCIENCE & STEM CELLS, STEM CELLS FROM THE PAST, STEM CELLS IN THE NEWS on January 14, 2017 at 12:34 pm

“Stunned?”
C’mon guys…

stroke

STROKE CLINICAL TRIALS

  • The University of Texas, Health Science Center at Houston July 1, 2009       Several months after becoming the first patient in the United States to undergo a revolutionary new stroke treatment, Roland “Bud” Henrich continues to improve. Doctors intravenously injected Henrich, 61, with stem cells taken from his own bone marrow…”The stem cells, we believe, may help repair the damage to his brain caused by the stroke,” said Sean Savitz, M.D., assistant professor of neurology at The University of Texas Medical School at Houston and the study’s lead investigator. “Animal studies have shown that when you administer stem cells after stroke, the cells enhance the healing. We know that stem cells have some kind of guidance system and migrate to the area of injury. They’re not making new brain cells but they may be enhancing the repair processes and reducing inflammatory damage.” http://www.texmedctr.tmc.edu/root/en/TMCServices/News/2009/07-01/Stem+Cells+Tested+for+Treatment+of+Stroke.htm

Other STROKE articles:

  1. https://repairstemcell.wordpress.com/2010/09/21/autologous-neural-stem-cells-benefit-parkinson%e2%80%99s-patients-adultstemcell-com/
  2. https://repairstemcell.wordpress.com/2010/09/20/stem-cell-treatment-for-stroke-and-traumatic-brain-injury-wholewellness-net/
  3. http://www.scientificamerican.com/article.cfm?id=can-stem-cells-block-stroke-damage
  4. http://www.sciencedaily.com/releases/2011/08/110831160216.htm
  5. https://repairstemcell.wordpress.com/2010/04/28/stem-cells-from-menstrual-blood-may-benefit-stroke-patients/
  6. http://www.philly.com/philly/health/HealthDay686541_20140407_Stem_Cells_Show_Pro

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New Stem Cell Treatment Leaves Scientists “Stunned” As Wheelchair-Bound Stroke Patient Walks Again

MORE THAN 70 PERCENT OF STROKE PATIENTS END UP WITH LONG-TERM DISABILITIES.

Researchers are said to be “stunned” by the success of a recent clinical trial of a new stem cell treatment for stroke patients. By injecting the cells into participants’ brains, scientists were able to produce some remarkable improvements, with several patients regaining motor function in their limbs.

A full report of the study has been published in the journal Stroke, with lead author Gary Steinberg telling the Washington Post that patients’ improvements were “not just minimal recovery like someone who couldn’t move a thumb now being able to wiggle it. It was much more meaningful. One 71-year-old wheelchair-bound patient was walking again.”

The trial involved the use of modified bone marrow–derived mesenchymal stem cells, which were injected into the specific region of each patient’s brain that had become damaged following their stroke. Amazingly, the researchers were not actually expecting to see any clinically relevant results at this stage, as they were just testing out a low dose of the treatment in order to assess its safety.

However, of the 18 patients involved in the study, seven experienced dramatic improvements in their cognitive and motor capabilities. In terms of safety, the study authors report that all participants experienced at least one temporary adverse effect, ranging from headaches and nausea to muscle spasticity. Importantly, though, all of these are thought to have been caused by the surgical procedure itself rather than the stem cells.

 

To evaluate the success of the treatment, the researchers used a number of standardized scales that are commonly used to assess the severity of symptoms in stroke patients. For instance, the Fugl-Meyer motor function total score is often used to measure recovery, with an improvement of 10 points representing a “clinically meaningful” change.

The patients involved in the study experienced an average improvement of 11.4 points on this scale, which translated into a “clinical improvement in the power of upper and lower limbs, ranging from an improvement in the ability to stand to the disappearance of tremor.”

Furthermore, the study authors make a point of noting that their patients had been suffering from their various symptoms for an average of 22 months prior to treatment. This is well beyond the six-month cut-off period that is typically considered to represent the point at which stroke-related brain damage becomes permanent and untreatable.

Exactly how the treatment works is not entirely understood, although Steinberg suspects that the stem cells somehow kick-start the brain’s own ability to repair itself, rather than developing into new neurons themselves.

Given that at present, more than 70 percent of people who suffer strokes end up with some sort of enduring disability, this new treatment could potentially be a game-changer – although more trials will be needed before it becomes readily available.

 

http://www.iflscience.com/brain/new-stem-cell-treatment-leaves-scientists-stunned-as-wheelchairbound-stroke-patient-walks-again/

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STEM CELLS IN 2000 – The pope, Bill Clinton and stem cells (a look back)

In ALL ARTICLES, RELIGION & STEM CELLS, STEM CELLS FROM THE PAST, STEM CELLS IN THE NEWS on September 28, 2011 at 12:46 pm

STEM CELLS IN 2000 – The pope, Bill Clinton and stem cells (a look back)

popejohnpaul_billclinton

popejohnpaul_billclinton


September 02, 2000 -By Gordon Prather

© 2009 WorldNetDaily.com

Well, you probably don’t expect Pope John Paul II and Bible-toting Bill to agree on abortion. So you were probably not surprised that, after Clinton announced the Final Federal Guidelines on Pluripotent Stem Cell research

last week, the pope immediately addressed in English an international congress being held in Rome of the Transplantation Society.

The Pope said, “Attempts at human cloning with a view to obtaining organs for transplants … insofar as they involve the manipulation and destruction of human embryos, are not morally acceptable.”

Now some newsies reported that the pope had come out against “cloning” humans, which he hadn’t. And from some news accounts you may have supposed that Bill Clinton had completely reversed his position of only three years ago, prohibiting the cloning of humans, which he hadn’t.

http://www.worldnetdaily.com/news/article.asp?ARTICLE_ID=20079

Man appears free of HIV after stem cell transplant – FOR 3 YEARS!

In STEM CELLS FROM THE PAST, VICTORIES & SUCCESS STORIES on December 10, 2010 at 7:43 am
Man appears free of HIV after stem cell transplant – FOR 5 YEARS! …and now there are TWO MORE HIV FREE PATIENTS!!!
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UPDATE TO STORY!!  Jul 26, 2012 3:06pm
Two More Patients HIV-Free After Bone Marrow Transplants

https://repairstemcell.wordpress.com/2012/09/12/two-more-patients-hiv-free-after-bone-marrow-transplants-abc-news/

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THE SIMPLE STORY

  1. 42 year old man has leukemia.
  2. 42 year old man also has HIV.
  3. Man needs bone marrow transplant for leukemia.
  4. Creative doctor uses bone marrow from “retrovirus resistant” donor (the donor can NOT get HIV due to a genetic mutation).
  5. Procedure costs about $150,000 (“retrovirus resistant” donors are very rare and very hard to find).
  6. 42 year old man’s body “TAKES ON” the retrovirus resistance from the donor’s bone marrow.
  7. 42 year old man’s symptoms go away and stay away for one year, two years, 3 years, 4 years  next month.
  8. 42 year old man is now a 46 year old man with no leukemia and no HIV to be found in his body.

SOME DETAILS

  • Doctors have not been able to detect the virus in his blood since about Jan of 2007.
  • In this case, there were 80 compatible blood donors living in Germany and on the 61st sample tested, they found one with the “retrovirus resistant” mutation from both parents.
  • There were no embryonic stem cells involved in this.  The stem cells in bone marrow are adult stem cells only.  Any time you see the words “treated” or “improved” or “recovered” associated with the words “stem cells”, assume it was from adult or repair stem cells until proven otherwise. https://repairstemcell.wordpress.com/stem-cells-for-newbies/

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STEM CELLS AND HIV – SOME PRE-HISTORY

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HISTORY OF THIS STORY (scroll down for full articles below)

  1. The original article that got almost no coverage is from Wall Street Journal – Nov 2008
  2. This article was then posted here in Feb 2009https://repairstemcell.wordpress.com/2009/02/20/stem-cells-hiv-part-2-a-doctor-a-mutation-and-a-potential-cure-for-aids-wsjcom/
  3. The abstract of the case was posted in the New England Journal of Medicine in Feb 2009 – See abstract below
  4. One of the most recent articles was in foxnews.com Dec 2010

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THE NOVEMBER 7, 2008 STORY

A Doctor, a Mutation and a Potential Cure for AIDS – A Bone Marrow Transplant to Treat a Leukemia Patient Also Gives Him Virus-Resistant Cells; Many Thanks, Sample 61

“A 42-year-old HIV patient with leukemia appears to have no detectable HIV in his blood and no symptoms after a stem cell transplant from a donor carrying a gene mutation that confers natural resistance to the virus that causes AIDS, according to a report published Wednesday in the New England Journal of Medicine.”

WHAT REALLY HAPPENED?

The startling case of an AIDS patient who underwent a bone marrow transplant to treat leukemia is stirring new hope that gene-therapy strategies on the far edges of AIDS research might someday cure the disease.

The patient, a 42-year-old American living in Berlin, is still recovering from his leukemia therapy, but he appears to have won his battle with AIDS. Doctors have not been able to detect the virus in his blood for more than 600 days, despite his having ceased all conventional AIDS medication. Normally when a patient stops taking AIDS drugs, the virus stampedes through the body within weeks, or days.

[Dr. Gero Hutter]
Sixten Koerper
Dr. Gero Hütter isn’t an AIDS specialist, but he ‘functionally cured’ a patient, who shows no sign of the disease.

“I was very surprised,” said the doctor, Gero Hütter.

The breakthrough appears to be that Dr. Hütter, a soft-spoken hematologist who isn’t an AIDS specialist, deliberately replaced the patient’s bone marrow cells with those from a donor who has a naturally occurring genetic mutation that renders his cells immune to almost all strains of HIV, the virus that causes AIDS.

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THE December 14, 2010 STORY

Doctors Claim HIV-Positive Man Cured by Stem Cell Transplant

Published December 14, 2010 – | FoxNews.com

There’s an estimated 33 million people worldwide living with HIV/AIDS, and now doctors believe one of them may have been cured of the virus after receiving a stem cell transplant in 2007, the medical journal Blood reported.

Timothy Ray Brown, an HIV-positive American living in Germany, had leukemia and was undergoing chemotherapy, when he received a transplant of stem cells from a donor carrying a rare, inherited gene mutation that seems to make carriers virtually immune to HIV infection.

The transplant appeared to wipe out both diseases, giving hope to doctors, but Dr. Anthony Fauci, director of the National Institutes of Allergy and Infectious Diseases, who has been studying HIV/AIDS for almost 30 years, said while this is an interesting proof of concept, it’s absurdly impractical.

“It’s hard enough to get a good compatible match for a transplant like this,” Fauci told FoxNews.com, “But you also have to find compatible donor that has this genetic defect, and this defect is only found in 1 percent of the Caucasian population and zero percent of the black population. This is very rare.”

Fauci said while this patient is “functionally cured” this is not something you can do with every HIV-infected individual.

“This is not prime time to me at all,” he said. “This is a very unusual situation that has little practical application for a simple reason. This donor not only had to be a good compatible match, but the donor had to have a genetic defect of cells that do not express the receptor that the HIV virus needs to enter the cell.”

Fauci also pointed to the fact that this transplant process is not only expensive, it’s incredibly painful and complicated, and requires the patient to start a whole new regimen of drugs.

“This patient is trading one poison for another. He may not have to be on antiretroviral drugs anymore, but he has to take immunosuppressant drugs now to prevent the rejection of his transplant cells. Again, what this is, is an interesting proof of concept, but it’s absolutely impractical.”

Dr. Thomas Quinn, director of Johns Hopkins Center for Global Health told FoxNews.com that he is very familiar with the “Berlin patient” case.

“This was a new report that looked much deeper into whether HIV could still be present or lurking in the body in some way, not cured, and since the transplant he remains viral free and his cells appear to be resistant to infection,” he said.

Quinn said he agrees with the researchers on this case that it would be qualified as the first HIV cure, opening the door to alternative means of curing HIV.

“He [Brown] has been without therapy for three years and appears to be free of the virus,” he said. “It gives hope to the millions of people infected with HIV that cure is a feasible option in the future.”

Even though Brown’s procedure proved to be successful, Quinn also warns that this was a rare case and a bone marrow transplant is not a cure-all for other HIV patients.

“It is a near fatal procedure that he had to have done because of the leukemia, but this procedure is very expensive and you have to be transplanted with a donor who is shown to be already resistant to HIV,” Quinn said. “You’re asking for a tall order to replicate this in the future.”

Brown’s case was published in a February 2009 issue of the New England Journal of Medicine

Read more: http://www.foxnews.com/health/2010/12/14/doctors-claim-hiv-positive-man-cured-stem-cell-transplant/#ixzz18Cug4Euz

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THE ABSTRACT FROM NEW ENGLAND JOURNAL OF MEDICINE

Volume 360:692-698  February 12, 2009  Number 7
NextNext

Long-Term Control of HIV by CCR5 Delta32/Delta32 Stem-Cell

Transplantation

Gero Hütter, M.D., Daniel Nowak, M.D., Maximilian Mossner, B.S., Susanne Ganepola, M.D., Arne Müßig, M.D., Kristina Allers, Ph.D., Thomas Schneider, M.D., Ph.D., Jörg Hofmann, Ph.D., Claudia Kücherer, M.D., Olga Blau, M.D., Igor W. Blau, M.D., Wolf K. Hofmann, M.D., and Eckhard Thiel, M.D.

SUMMARY

Infection with the human immunodeficiency virus type 1 (HIV-1)requires the presence of a CD4 receptor and a chemokine receptor,principally chemokine receptor 5 (CCR5). Homozygosity for a32-bp deletion in the CCR5 allele provides resistance againstHIV-1 acquisition. We transplanted stem cells from a donor whowas homozygous for CCR5 delta32 in a patient with acute myeloidleukemia and HIV-1 infection. The patient remained without viralrebound 20 months after transplantation and discontinuationof antiretroviral therapy. This outcome demonstrates the criticalrole CCR5 plays in maintaining HIV-1 infection.
Source Information

From the Department of Hematology, Oncology, and Transfusion Medicine (G.H., D.N., M.M., S.G., A.M., O.B., I.W.B., W.K.H., E.T.) and the Department of Gastroenterology, Infectious Diseases, and Rheumatology (K.A., T.S.), Campus Benjamin Franklin; and the Institute of Medical Virology, Campus Mitte (J.H.) — all at Charité Universitätsmedizin Berlin; and the Robert Koch Institute (C.K.) — all in Berlin.

Drs. Hofmann and Thiel contributed equally to this article.

Address reprint requests to Dr. Hütter at Medical Department III Hematology, Oncology, and Transfusion Medicine, Charité Campus Benjamin Franklin, Hindenburgdamm 30 D-12203 Berlin, Germany, or at gero.huetter@charite.de// <!–[CDATA[–>
var u = “gero.huetter”, d = “charite.de”; document.getElementById(“em0”).innerHTML = ‘‘ + u + ‘@’ + d + ”
// ]]>.

Full Text of this Article

This article has been cited by other articles:

  • Arababadi, M. K., Hassanshahi, G., Azin, H., Salehabad, V. A., Araste, M., Pourali, R., Nekhei, Z. (2010). No Association Between CCR5-{Delta}32 Mutation and Multiple Sclerosis in Patients of Southeastern Iran. Lab Med 41: 31-33 [Abstract] [Full Text]
  • Fauci, A. S., Folkers, G. K. (2009). Investing To Meet The Scientific Challenges Of HIV/AIDS. Health Aff (Millwood) 28: 1629-1641 [Abstract] [Full Text]
  • Bonsignori, M., Moody, M. A., Parks, R. J., Holl, T. M., Kelsoe, G., Hicks, C. B., Vandergrift, N., Tomaras, G. D., Haynes, B. F. (2009). HIV-1 Envelope Induces Memory B Cell Responses That Correlate with Plasma Antibody Levels after Envelope gp120 Protein Vaccination or HIV-1 Infection. J. Immunol. 183: 2708-2717 [Abstract] [Full Text]
  • Levy, J. A. (2009). The Unexpected Pleiotropic Activities of RANTES. J. Immunol. 182: 3945-3946 [Full Text]
  • (2009). All you need to read in the other general journals. BMJ 338: b627-b627 [Full Text]
  • (2009). Stem-Cell Transplantation Enables Long-Term HIV Control. AIDS Clin Care 2009: 1-1 [Full Text]
  • Levy, J. A. (2009). Not an HIV Cure, but Encouraging New Directions. NEJM 360: 724-725 [Full Text]

From http://content.nejm.org/cgi/content/short/360/7/692

Stem cell pioneer does a reality check – Cloning and stem cells- msnbc.com

In ALL ARTICLES, STEM CELLS FROM THE PAST, STEM CELLS IN THE NEWS on March 11, 2009 at 7:04 am

One of my favorite scientists and articles. Dr Thomson, father of embryonic stem cells, tells the real story! – dg

“…embryonic stem cells are not being used in any clinical applications yet, while alternatives such as adult stem cells figure in scores of therapies.”

“Ten or 20 years from now…there will be transplantation-based therapies, , but even if there was none, and it was a complete failure, this technology is extraordinarily important” Dr T.

James Thomson reflects on science and morality – Stem cell pioneer does a reality check

By Alan Boyle

Science editor – msnbc.com – updated 6:29 p.m. ET, Sat., June. 25, 2005

MADISON, Wis. — Seven years ago, when James Thomson became the first scientist to isolate and culture human embryonic stem cells, he knew he was stepping into a whirlwind of controversy.

He just didn’t expect the whirlwind to last this long.

In fact, the moral, ethical and political controversy is still revving up — in Washington, where federal lawmakers are considering a bill to provide more federal support for embryonic stem cell research; and in Madison, Thomson’s base of operations, where Wisconsin legislators are considering new limits on stem cell research.

Thomson, a developmental biologist and veterinarian at the University of Wisconsin at Madison, made history in 1998 when he and fellow researchers derived the first embryonic stem cell lines from frozen human embryos. The breakthrough came after the news that a sheep named Dolly was born as the first cloned mammal — and together, the two announcements hinted at a brave new world of medical possibilities and moral debates.

Some of Thomson’s other pronouncements might seem more surprising: that supporters of stem cell research are overestimating the prospects for transplantation cures, that the current stem cell lines aren’t well-suited for such applications anyway, and that there’s no need to resort to therapeutic cloning right now — or perhaps ever.

Critics point out that embryonic stem cells are not being used in any clinical applications yet, while alternatives such as adult stem cells figure in scores of therapies. Thomson acknowledged that the field was still in its formative stage: “There have been companies that have gone into stem cells, but nobody’s made any money.”

But he recently helped found a biotech start-up called Cellular Dynamics International that takes a different approach, aiming eventually to turn embryonic stem cells into human heart cells suitable for drug testing. “Nobody’s been able to test heart drugs on heart cells [outside the human body] before,” he said. “That will change medicine a lot quicker than actually transplanting those heart cells.”

Thomson predicted that in the long run, embryonic stem cells would play a more important role in fundamental research than in transplantation therapies — a view that doesn’t sit well with the critics.

“You have to ask the question, why would you destroy living human embryos just to study them?” said Barbara Lyons, executive director of Wisconsin Right to Life.

In last week’s wide-ranging interview, Thompson explained the reasons behind the research, and touched on many other scientific and moral issues as well. Here is an edited transcript:

MSNBC: How do see this research developing in the next few years?

Thomson: I want to make a basic statement first — which almost never gets in the press, but I keep trying — on what I see as the legacy of these cells.

One is the basic science, and simply having better access to the human body. That’s the most important legacy. I’m very hopeful that there will be some transplantation applications for this technology, but they’re going to be very challenging. And it’s been so hyped in the press that people expect it to come the day after tomorrow. …

Ten or 20 years from now, I’m actually currently optimistic that there will be transplantation-based therapies, but even if there was none, and it was a complete failure, this technology is extraordinarily important.

via Stem cell pioneer does a reality check – Cloning and stem cells- msnbc.com.

Stem Cells Redux

In ALL ARTICLES, STEM CELLS FROM THE PAST, STEM CELLS IN THE NEWS on March 11, 2009 at 1:33 am

Stemagen via Bloomberg News -Updated: March 9, 2009

Stem cells are how we all begin: undifferentiated cells that go on to develop into any of the more than 200 types of cell the adult human body holds.

Few quarrel with predictions of the awesome potential that stem cell research holds. One day, scientists say, stem cells may be used to replace or repair damaged cells, and have the potential to drastically change the treatment of conditions like cancer, Alzheimer’s and Parkinson’s disease and even paralysis.

All of these disease are already being treated outside the US with Adult/Repair stem cells. -dg

But the divisions over how to conduct that research have been deep and bitter. Most research has been conducted on embryonic stem cell lines  (in the US only! – dg) — cultures of cells derived from four- or five-day-old embryos, or fertilized cells. Opponents of embryonic stem cell research, which often uses embryos discarded by fertility clinics, want it to be severely restricted or banned outright as inhumane.

(actually, some don’t care about the moral issues, they just want the dying and debilitated to have opportunities for treatment ASAP! – dg)

The most important legislation relating to stem cell research is known as the Dickey-Wicker amendment, which first became law in 1996, and has been renewed by Congress every year since. It specifically bans the use of tax dollars to create human embryos – a practice that is routine in private fertility clinics – or for research in which embryos are destroyed, discarded or knowingly subjected to risk of injury.

via Stem Cells.

OHIO COUPLE HOPES BABY’S MARROW WILL SAVE SISTER, 1990, 92, 95 & 2008

In ALL ARTICLES, STEM CELLS FROM THE PAST, VICTORIES & SUCCESS STORIES on February 27, 2009 at 2:38 am

THRIVING: Mary Ayala poses with daughters Marissa, left, and Anissa. Marissa saved the life of her sister Anissa with a bone marrow transplant in 1991.

THRIVING: Mary Ayala poses with daughters Marissa, left, and Anissa. Marissa saved the life of her sister Anissa with a bone marrow transplant in 1991.

1995

OHIO COUPLE HOPES BABY’S MARROW WILL SAVE SISTER

Published: Monday, April 3, 1995 12:00 a.m. MDT

The final stage has just begun for a couple who decided to have another child in order to give their 6-year-old daughter a chance to survive leukemia.

Christy Schwartz received high doses of chemotherapy over the weekend. She also will receive intensive radiation treatments to prepare her for a bone marrow transplant on Thursday.The procedure would kill Christy without the transplant.

“She is almost going to be dead and brought back,” her mother said.

Doctors say there is a 20 percent to 30 percent chance a transplant will cure Christy, who was diagnosed with leukemia when she was 11 months old.

She will receive stem cells extracted from her little sister Angelina’s umbilical cord just days after her birth in November. Stem cells are a component of marrow that create new blood cells.

Angelina, now four months old, is the fourth child of Jill and Randy Schwartz. They decided to conceive her after learning that no other family member’s bone marrow matched Christy’s, and that no suitable donor could be found in the National Bone Marrow Registry.

The couple got the idea after Jill Schwartz read about the Ayala family of San Bernardino, Calif., whose teenage daughter, Anissa, had leukemia. In 1991, Anissa received bone marrow from her baby sister, Marissa, who was conceived to provide a match despite criticism from medical ethicists.

That transplant was successful. Anissa is now 22, and still in remission. Marissa is 4.

There was only a one-in-four chance Angelina’s marrow would match Christy’s. A test 16 weeks into Jill Schwartz’s pregnancy confirmed they had beaten the odds.

“Ethically this is OK, as long as their motives are mixed: They want the child and they want to save their other kid,” said Dr. Arthur L. Caplan, director of the Center for Bioethics at the University of Pennsylvania.

via Deseret News Archive | OHIO COUPLE HOPES BABY’S MARROW WILL SAVE SISTER.

1990

It was at City of Hope that Anissa Ayala of Hacienda Heights, California was received a miracle in the 1990s. Diagnosed with acute leukemia, doctors and researchers were able to use umbilical cord cells from her younger sister Marissa to stop the spread of the leukemia and give Anissa a second chance at life. – http://scottrobinsonhondainthecommunity.com/

1992

Lifesaving Tot Again Helps Sister – As A Flower Girl

SAN BERNARDINO, Calif. – Anissa Ayala and her little sister, Marissa Eve, walk down the aisle this evening as bride and flower girl, one year after a bone-marrow transplant to which both owe their lives.

Marissa, now 2 1/2, was conceived to donate marrow to her big sister, who suffered from a deadly form of leukemia.

“Four years ago, things looked so gloomy, and now Anissa’s doing great,” her father, Abe Ayala, said on the eve of the wedding. “We’re being so rewarded. It’s amazing.”

Anissa, 20, and Bryan Espinosa, 25, are to marry before 350 guests at a Victorian mansion in this city 50 miles east of Los Angeles.

http://community.seattletimes.nwsource.com/archive/?date=19920605&slug=1495590

Ayala sisters appear on national TV -Siblings recently profiled in the Register regarding landmark bone-marrow transplant featured on ‘Good Morning America.’
By GREG HARDESTY – Wednesday, July 30, 2008 -The Orange County Register

PLACENTIA – Two sisters recently profiled in the Register regarding their landmark bone-marrow transplant 17 years ago appeared live on a national television program this morning  and kicked off a campaign to raise money for cancer research.

To view the seven-plus-minute segment on ABC’s “Good Morning America,” click here http://abcnews.go.com/gma. In the middle of the page, under the “Recently on GMA” and “Today” headline, click on the item headlined, “Having a Child to Save Your Child.”

Anissa Ayala, 36, of Placentia, and Marissa Ayala, 18, of Walnut, made the cover of Time magazine in 1991 for what was then a controversial and landmark donor story.

Marissa was conceived to save the life of her sister, who had leukemia, and was 14 months old when her marrow was transplanted into Anissa, then 19.

WHAT DO THE ACADEMY AWARDS, CHILI & DOLLY THE SHEEP HAVE IN COMMON?

In ALL ARTICLES, STEM CELLS FROM THE PAST, STEM CELLS IN THE NEWS on February 22, 2009 at 2:21 pm
drew-barrymore

drew-barrymore

Tonight, movie stars will be walking down a red carpet and you can watch them on TV from home or party with an academy of people at a nearby Oscar party.

In honor of National Chili Day, check out some local establishments serving up their chili recipes. Also, perhaps you should try to get in a game of golf for But don’t forget to recognize Walking the Dog Day and take your pooch out for a much needed stroll.Golf In America Day. Even if there’s still snow on the ground in your neighborhood, you might be able to swing a club a little. You just won’t be able to see where the ball went .

Today Was …
… the day in 1997 when scientists in Roslin, Scotland announced that they’d successfully cloned a sheep named Dolly. … the day in 1959 when Lee Petty won the first Daytona 500 … the day in 1989 when Jethro Tull won the first heavy metal Grammy

CATCH UP…with a twist! (Part 2) – Stem Cell Breakthrough Helps 85% Of Type 2 Diabetes Patients

In ALL ARTICLES, CATCH UP!, STEM CELLS FROM THE PAST, VICTORIES & SUCCESS STORIES on February 20, 2009 at 3:14 am

Stem Cell Breakthrough Helps 85% Of Type 2 Diabetes Patients.  Yes this is an amazing breakthrough…but what is more amazing is that it took place a full 3 years ago!  At this rate, the US will never CATCH UP! to Dr Vina.  –  DG

CATCH UP!

CATCH UP!

Stem Cell Breakthrough Helps 85% Of Type 2 Diabetes Patients

Article Date: 07 Feb 2006 – 4:00 PST

A study carried out in Argentina by a team of researchers from a Not-For-Profit Organization called ‘Don Roberto Fernandez Vina Foundation’ (San Nicolas- Buenos Aires, Argentina) demonstrated that stem cells implanted into type 2 diabetes patients, in direct form into the pancreas, improve the production of Endogenous Insulin, increase the levels of “C Peptide”, decrease blood glucose levels and glycated hemoglobin levels faster than other treatments. 84% of the patients that had received the autologuous bone marrow cells could also abandon the drugs that stimulate insulin production or the insulin that they had been receiving previously.

There were no complications at all, demonstrating the safety of the technique, since the extraction, the cellular implants and evolution of the patients…

via Stem Cell Breakthrough Helps 85% Of Type 2 Diabetes Patients.

Of stem cells, what would Gandhi say? (2005)

In ALL ARTICLES, STEM CELLS FROM THE PAST, STEM CELLS IN THE NEWS on February 15, 2009 at 9:58 am

Of stem cells, what would Gandhi say?
By Pankaj Mishra
Published: MONDAY, AUGUST 22, 2005

LONDON: In 2001, President George W. Bush restricted U.S. federal financing for stem cell research. The decision, which was shaped at least partly by the Republican Party’s evangelical Christian base, and which disappointed many American scientists and businessmen, provoked joy in India.

The weekly newsmagazine India Today, read mostly by the country’s ambitious middle class, spoke of a “new pot of gold” for Indian science and businesses. “If Indians are smart,” the magazine said, American qualms about stem cell research “can open an opportunity to march ahead.”

Just four years later, this seems to have occurred. According to Ernst & Young’s Global Biotechnology Report in 2004, Indian biotechnology companies are expected to grow tenfold in the next five years, creating more than a million jobs. With more than 10,000 highly trained and cheaply available scientists, the country is one of the leading biotechnology powers along with Korea, Singapore, China, Japan, Sweden, Britain and Israel.

A top Indian corporation, the Reliance Group, owns Reliance Life Sciences, which is trying to devise new treatments for diabetes and Parkinson’s and Alzheimer’s diseases, and create human skin, blood and replacement organs genetically matched to their intended recipients.

Some scientists have even more ambitious ideas. Encouraged by the cloning of a sheep by British scientists in 1996, they plan to do the same with endangered species of Indian lions and cheetahs.
excerpted from http://www.iht.com/articles/2005/08/21/news/india.php?page=1

STEM CELLS IN 1991

In ALL ARTICLES, STEM CELLS FROM THE PAST on February 10, 2009 at 2:17 am
BONE MARROW STEM CELL

BONE MARROW STEM CELL

1991

Scientists Claim to Have Isolated Stem Cells

By SANDRA BLAKESLEE

Published: November 5, 1991

A CALIFORNIA researcher described yesterday how he and colleagues had isolated human stem cells, the cells that give rise to all cells of the human immune and blood system.

If the long-sought achievement can be confirmed, it could lead to ways to treat cancer, AIDS, sickle cell anemia and many other diseases, the scientists said. It could also improve the chances of success for organ transplants.

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via Scientists Claim to Have Isolated Stem Cells – New York Times.

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