DAVID GRANOVSKY

Archive for April, 2013|Monthly archive page

MMR VACCINE AND AUTISM – THE SCIENCE

In ALL ARTICLES, OFF THE BEATEN PATH on April 30, 2013 at 6:56 pm

autism scientific america

TRYING TO GET A HANDLE ON THE MMR/VACCINE CONTROVERSY:

I don’t know what causes Autism but I believe in education, knowledge and research.

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Baby monkeys given standard doses of popular vaccines develop autism symptoms

“…a macaque monkey (primates) study of the very same vaccines given to children during 1994-1999, i.e., the Measles-Mumps-Rubella (MMR) vaccine and several Thimerosal mercury-containing vaccines injected into children during that time frame when the autism spectrum disorder skyrocketed.”

The original Study here:

Influence of pediatric vaccines on amygdala growth and opioid ligand binding in rhesus macaque infants: A pilot study   http://www.ane.pl/pdf/7020.pdf

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WHAT ARE THE ADVERSE REACTIONS FROM MMR VACCINES?
http://www.merck.com/product/usa/pi_circulars/m/mmr_ii/mmr_ii_pi.pdf
(The warnings from the manufacturer are scary enough, even if it doesn’t cause autism.)

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WORLD STUDIES ON MMR/AUTISM:

Here is a list of 28 studies from around the world from (mercola.com) that support Dr. Wakefield’s controversial findings:

  1. The Journal of Pediatrics November 1999; 135(5):559-63
  2. The Journal of Pediatrics 2000; 138(3): 366-372
  3. Journal of Clinical Immunology November 2003; 23(6): 504-517
  4. Journal of Neuroimmunology 2005 
  5. Brain, Behavior and Immunity 1993; 7: 97-103
  6. Pediatric Neurology 2003; 28(4): 1-3
  7. Neuropsychobiology 2005; 51:77-85
  8. The Journal of Pediatrics May 2005;146(5):605-10
  9. Autism Insights 2009; 1: 1-11
  10. Canadian Journal of Gastroenterology February 2009; 23(2): 95-98
  11. Annals of Clinical Psychiatry 2009:21(3): 148-161
  12. Journal of Child Neurology June 29, 2009; 000:1-6
  13. Journal of Autism and Developmental Disorders March 2009;39(3):405-13
  14. Medical Hypotheses August 1998;51:133-144.
  15. Journal of Child Neurology July 2000; ;15(7):429-35
  16. Lancet. 1972;2:883–884.
  17. Journal of Autism and Childhood Schizophrenia January-March 1971;1:48-62
  18. Journal of Pediatrics March 2001;138:366-372.
  19. Molecular Psychiatry 2002;7:375-382.
  20. American Journal of Gastroenterolgy April 2004;598-605.
  21. Journal of Clinical Immunology November 2003;23:504-517.
  22. Neuroimmunology April 2006;173(1-2):126-34.
  23. Prog. Neuropsychopharmacol Biol. Psychiatry December 30 2006;30:1472-1477.
  24. Clinical Infectious Diseases September 1 2002;35(Suppl 1):S6-S16
  25. Applied and Environmental Microbiology, 2004;70(11):6459-6465
  26. Journal of Medical Microbiology October 2005;54:987-991
  27. Archivos venezolanos de puericultura y pediatría 2006; Vol 69 (1): 19-25.
  28. Gastroenterology. 2005:128 (Suppl 2);Abstract-303

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Dr. Wakefield’s Latest: MMR And Autism

http://articles.mercola.com/sites/articles/archive/2008/01/02/mmr-and-autism-part-two.aspx

References/Notes

1. Plotkin SA, Mortimer EA. (eds.) Vaccines, Philadelphia, W. B. Saunders, 1994. This collection of articles has a wealth of medical information about vaccines.

2. See details at http://www.cdc.gov/nip/registry.

3. “The effect of routine infant vaccination on acute disease incidence may not be apparent for 20-30 years because currently most infections occur among young adults.” Morbidity and Mortality Weekly Report, Vol. 44, No. 30, Aug. 4, 1995.

4. “In a sudden reversal of health policy, France has decided to suspend Hepatitis B vaccinations in secondary schools because of fears that the vaccine causes neurological disorders.” New York Times, Oct. 3, 1998.

5. ACIP meeting minutes, Feb. 1998. Available from CDC.

6. The Economist 1998;344(8044):95(3). It suggested possible correlations between vaccines and other diseases such as asthma.

7. Patton CV, Sawicki DS. Basic Methods of Policy Analysis, Prentice Hall, 1993.

8. ACIP Policies and Procedures, July 1998. Available from the CDC or from Some other supporting evidence on immunization policy is also there.

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Measles-Mumps-Rubella (MMR) Vaccine as a Potential Cause of Encephalitis (Brain Inflammation) in Children

http://articles.mercola.com/sites/articles/archive/2008/01/02/mmr-vaccine-part-three.aspx

References for this article:

1. Statements by Bernard Rimland, PhD, were given at a conference on autism, sponsored by the Autism Research Institute in Chicago, June, 1996.

2. Information from the Developmental Delay Registry, 6701 Fairfax Road, Chevy Chase, Maryland 20815, Tel. 301652-2263.

3. From a paper distributed by Dawbarns Law Firm, Bank House, Kingrs Staithe Square, Lingrs Lynn, Norfolk PE30 IRD, Great Britain, Tel. 01553. 764373, Fax 01553-765226.

4. Singh VJ et al., Antibodies to myelin basic protein in children with autistic behavior, Brain, Behavior, and Immunity, Vol. 7, 97-1203, 1993.

5. Kumar S & Miller LK, Effects of serial passage of Autographs Californica nuclear polyhidrosis virus in cell culture. Virus Research, Vol. 7, 335-349, 1987.

6. Jahnke U et al., Sequence homology between certain viral proteins and proteins related to encephalomyelitis and neuritis, Science, Vol. 29, 282-284, July 19, 1985,

7. Presentation by Dr. Vijendra Singh, August 16, 1997, Allegro School, Cedar Knolls, New Jersey.

8. Scott HD et al., Physician reporting of adverse reactions: results of the Rhode Island adverse drug reaction reporting project, JAMA, Vol. 263, No. 13, 1785-1788, April 4, 1990.

9. Reporting side effects: signals or noise? (Editorial), ibid, page 1823.

10. Gupta S et al., Dysregulated immune system in children with autism; beneficial effects of intravenous globulin on autistic characteristics, J ofAutism and Develop Disorders, Vol. 26, No. 4, 439-452, 1996. (In this article on page 450, it is stated, “We theorized that the high titers of rubella antibody … present in mothers of children with autism would be transplacentally transferred and may persist for a prolonged period in the child. When such a child gets MMR immunization, rubella antigen may complex with preexisting antibodies and such complexes might play a role in pathogenesis of autistic features.”)

11. Dublin L & Lotka A, Twenty-five Years ofHealth Progress, New York: Metropolitan Life Insurance Company, 1937, page 48.

12. Dublin L, Health Progress 1936-1945, New York: Metropolitan Life Insurance Company, 1948, page 12.

13. Vaccination. 100 Years of Orthodox Research Shows that Vaccines Represent a Medical Assault on the Immune System, Viera Scheibner, PhD., 1993 (from pages 33 to 49 the author extensively reviews the Swedish and Japanese experiences with the pertussis vaccine, book available from New Atlantean Press, P.O. Box 9638-925, Santa Fe, New Mexico 87504).

14. Garenne M et al., Child mortality after high-titre measles vaccines; a prospective study in Senegal, Lancet, Vol. 338, 903-907, October 12, 1991.

15. Hussey GD et al., The effect of Edmonston-Zagreb and Schwarz measles vaccines on immune responses in infants, J of Infect Diseases, Vol. 173, 1320-1326, 1996.

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Italian court reignites MMR vaccine debate after award over child with autism

http://www.independent.co.uk/life-style/health-and-families/health-news/italian-court-reignites-mmr-vaccine-debate-after-award-over-child-with-autism-7858596.html?origin=internalSearch

Original Articles in Italian:

MMR e Autismo: il caso Wakefield come emblema del “COVER-UP scientifico”

… per tutte sulla vicenda Wakefield e la correlazione fra MMR e Autismo. Innanzitutto vi segnaliamo il pregevole lavoro che il sito … i n discussione la procedura di valutazione dei vaccini MMR in Gran Bretagna fin dal lontano 1987 e conferma la sostanziale assenza di …

News – thinknew – 28/09/2012 – 08:05 – 0 comments – 1 allegato

MMR: la Vittoria di una Madre

… apparso il 16 giugno 2012 su “Daily Mail” con il titolo “MMR: A mother’s victory. The vast majority of doctors say there is no link …

Articolo – thinknew – 24/09/2012 – 13:17 – 0 comments – 0 allegati

Ascolta il Silenzio – Film

… i possibili legami tra la somministrazione del vaccino MMR, la malattia intestinale cronica e l’autismo.   Nonostante tutte le …

Argomento di discussione del forum – yellowbrain – 26/03/2013 – 19:58 – 0 comments – 0 allegati

Re: VACCINI OMEOPATICI

… 7 th November 1997″ , che riporta : ” MMR e SSPE ****** In una conferenza negli Stati Uniti, … potrebbe essere utile. ” originale: “MMR and SSPE****** at a conference in the US had suggested that the measles …

Commento – Lucas – 16/01/2013 – 00:19 – 0 comments – 0 allegati

Chi ha paura dell’uomo nero?

… di Valentino ( http://www.comilva.org/danno_da_vaccino/mmr_vittoria_di_madre ) poi dà particolarmente fastidio perché sbugiarda …

News – thinknew – 28/01/2013 – 11:35 – 0 comments – 0 allegati

Anonimo:Autismo e vaccino di MMR (orecc.morb.rosolia)

… sul collegamento di tale malattia con il vaccino di MMR (orecchioni – morbillo – rosolia). di: VICKY COLLINS Gordon Bell, … molto stretta tra l’autismo ed il vaccino di MMR(orecchioni – morbillo – rosolia) indicando che i bambini autistici … volta presenti a livelli così elevati, causa il vaccino MMR, scatenano in un organismo così debole nel sistema immunitario come quello …

Argomento di discussione del forum – OldForum – 30/07/2002 – 00:00 – 0 comments – 0 allegati

Anonimo:Il legame tra MMR e autismo.

… prove schiaccianti relative al legame fra la vaccinazione MMR (orecchioni – morbillo – rosolia) l’autismo e le malattie intestinali nei … urgentemente nuovi parametri sulla sicurezza del vaccino MMR – la vaccinazione combinata per orecchioni, morbillo e rosolia che viene …

Argomento di discussione del forum – OldForum – 02/08/2002 – 00:00 – 0 comments – 0 allegati

Londra. 40 bambini uccisi dal vaccino MMR

… (Discussioni Libere) …

Argomento di discussione del forum – alsa – 11/12/2010 – 11:50 – 0 comments – 0 allegati

Anonimo:ProQuad il nuovo vaccino MMR+ sicuro.

… bambini sono stati sottoposti ad iniezione del vaccino di Mmr (morbillo parotite rosolia), e una seconda iniezione di Varivax …

Argomento di discussione del forum – OldForum – 15/04/2003 – 00:00 – 3 comments – 0 allegati

Richiamo vaccinazione MMR

Ho appena scoperto il vostro forum e ne approfitto subito per chiedervi un’opinione: ho ricevuto la lettera della ASL (provincia di Milano) in cui mi invitano a presentarmi con il mio bambino di 6 anni per il richiamo di Morbillo-Rosolia-Parotite. Allegan …

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RELATED ARTICLES:

FAKE AND FRAUDULENT SCIENCE

CDC VACCINE COVER UP – MERCURY ACTUALLY DOES CAUSE AUTISM?

AUTISM RETROSPECTIVE

Letters from Laura #1 – Autism, GI issues, chronic ear infections, breast cancer and Jenny McCarthy

AUTISM/ASPERGER’S + STEM CELLS

YOU MUST EMPTY YOUR MIND TO LEARN

In ALL ARTICLES, OFF THE BEATEN PATH on April 30, 2013 at 4:15 pm

keep-calm-and-empty-your-mind

I’m perplexed by an apparent dichotomy…

people who are staunch supporters of education and awareness whom are so set in their convictions they are unwilling to hear any thoughts but their own, unwilling to educate themselves on things they are wholly ignorant on, unwilling to budge or even have a calm, civil, open discussions on topics. Not argument, not debate, a friendly discussion whereby 2 people put their heads together to better understand each other and the world around them.

I invite everyone to have this type of discussion with each other and with me because I know I don’t know everything and the only way to learn is to keep your own damn mouth shut for a hot second and give your own damn opinion a rest for a second. The full glass can take no more water. Empty your mind to take on more.  that’s the only way it works.

http://www.youtube.com/watch?v=LTnSEFsInp0

be water my friend

CHILD RECEIVES NEW STEM CELL TRACHEA

In ALL ARTICLES, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on April 30, 2013 at 2:44 pm
ht_ciaran_finn_lynch_trachea_transplant_ll_120725_wg

Two years ago, 11 year old Ciaran Finn-Lynch, became the world’s first child to receive new trachea.  Scientists/doctors used the child’s own stem cells to rebuild the airway in his body.  This is the really cool stuff because the public can wrap their heads around it and see a trachea in a dish, a nose growing on an arm, etc.  The next step in evolution of the public consciousness is to get them to understand…we can regrow and heal the organs which are already present in their own bodies, already damaged and in need of fixing…with stem cells from their own body.  I think this will be difficult as the home owner with the means will almost always go to the outside plumber or the super store and get a new piece of equipment to replace the old rather than pick up a wrench and fix what they have already.  Another byproduct of the disposable society we live in.  Homes, cars, washing machines and now organs are believed to have a limited life span.  When it breaks, just buy a new one.  – DG

Here’s the article from ScienceDaily:

Surgeons Transplant New Trachea Into Child Using His Own Stem Cells to Rebuild Airway

http://www.sciencedaily.com/releases/2010/03/100325114400.htm

Which was written based on materials from the University College of London release (what, you thought this was in the US?):

UCL surgeons perform revolutionary transplant operation

http://www.ucl.ac.uk/news/news-articles/1003/10031903

trachea

Here’s the 2 year follow-up:

Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study.

http://www.ncbi.nlm.nih.gov/pubmed/22841419

And the human interest story coverage of the same:

Stunning Recovery for First Child to Get Stem Cell Trachea

http://abcnews.go.com/Health/stunning-recovery-child-stem-cell-trachea/story?id=16858771

AUTISM SPECTRUM, TREATMENTS AND CURES(?)

In ALL ARTICLES, OFF THE BEATEN PATH on April 30, 2013 at 10:13 am

autism-not-a-disease

What is the Autism Spectrum? What does it mean to Treat? Does treat mean Cure?

Let’s be clear, as clear as we can. Nothing applies to all but we speak of an autistic spectrum, a gross lumping together of many different variations.

“A spectrum (plural spectra or spectrums[1]) is a condition that is not limited to a specific set of values but can vary infinitely within a continuum…the autism spectrum. In these uses, values within a spectrum may not be associated with precisely quantifiable numbers or definitions. Such uses imply a broad range of conditions or behaviors grouped together and studied under a single title for ease of discussion.”

We use spectrum because it’s easier to do so and because we don’t have 100 different, perfectly defined types of Autism in the spectrum. We don’t have: “Jimmy Jones presents with ADS#72” and even if we did, it would probably look more like, “Jimmy Jones presents with ADS72 with non-specific characteristics of ADS34 and a dash of ADS9.” We are limited in that we have a spectrum, an umbrella of sorts with perhaps more dissimilarities than similarities between those on it but it’s the umbrella we have so let’s use it because it allows us to move forward on the discourse.

As for the term treat   and what I “mean” by it, now we are getting into strictly defined   terms.  Treat means:
1. To give medical aid to someone.
2. To give medical aid to counteract a disease or   condition.

Treat does not mean cure. .  Likewise, recovery does not mean remission. Asymptomatic does not mean therapeutic benefit.  A treatment, when applied to different people with the same condition or different people on a spectrum, may result in dissimilar responses or results. Some may recover, some may become asymptomatic, some may derive significant therapeutic benefit, some may derive lesser benefits and some may have no significant response to a treatment and some may have limited quantifiable change yet huge quality of life improvement.  I wish there were guarantees on treatments but there are not.

In addition, there are many different kinds of treatments stemming from different schools of thought on cause, affect, symptom alleviation, etc.  There is HBOC, MSC, Chelation Therapy, Nutritional Intervention, Gut Bacteria Proliferation, etc. and many studies showing their safety and efficacy and many swear by them.  Some of these treatments or therapies or interventions have worked for some on the spectrum and because it’s a spectrum, may not work on others. But we educate ourselves to what’s available and the new studies and advancements.

So, here are a few articles. Some will be relevant to your inquiries, some will not. I hope they are helpful and enlightening.  And this is not the sum total of the information out there, just a broad brush stroke collection.   I’ll keep looking and I’ll try to gather some more over the next few days to create a more comprehensive… spectrum…of data and information:  AUTISM AND STEM CELL TREATMENTS

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I’ll leave you with this one last thought.  I used the image at the top for a reason.  It is something I’ve been wrestling with quite a lot lately.  Is Autism an identity or a disability?  Should we search for a cure or try to understand it.  I wrote an article on the subject early this month – AUTISM: IDENTITY OR DISABILITY  

And a chicken and the egg scenario just occurred to me.  Simply put:

Stem cells are the body’s natural healing system.  If you implant stem cells into the body, it will begin to repair itself.  It is the job of the stem cell to assist your body in functioning as well as it possibly can.  Dead tissue can begin to regenerate, new tissue can begin to develop, genetic anomalies can begin to correct, etc.  The stem cells and the body “know” what needs to be done or even, what needs to be fixed.  We can force them to do ‘x’ but eventually they will go fix ‘y.’

So if stem cells ‘fix’ something, that means (at the very least) that the stem cells and your body believed it needed ‘fixing.’  So in the simplest of terms and the broadest of definitions, if stem cells fix Autism, was it not because it needed to be fixed?  I don’t know.  I’m asking.  Maybe you have a different view.  If you do, I’d love to hear it.

p.s. A “friend” noted that cure is perhaps not the best term to use and I agree.  We do need a new set of words. Both for that reason and because we need to start seeing people as people and not as patients and definitely not as diseases. 

Further, when I eat well it is not to cure, when I go to the gym it is not to cure, when I meditate or do yoga it is not to cure. All of these things are to maximize my life, my health, my soundness of body and mind, my time on this earth, not to cure. Part of the issue is that Western medicine treats illnesses not people…wait until someone is sick and then try to fix what’s wrong with them with zero ‘cures’ since Polio 1954.   A pretty backward way of thinking.  Eastern medicine prevents disease as a by product of the efforts taken to maximize one’s health, vitality and life. We could learn a lot from this attitude.

PARENTS WHO WILL STOP AT NOTHING TO HEAL THEIR OWN

In ALL ARTICLES, OFF THE BEATEN PATH on April 24, 2013 at 11:00 am

Dedicated to the amazing women (and men) who are doing everything in their power to heal their children…

Do not confuse them for a distracted and solitary parent sitting alone in a dark corner on a laptop, sipping a spritzer and dangling a toe into stem cell treatments.

These are parents who are researching for years, they network and talk to everyone they can get their hands on, they create pages and sites and media campaigns, they compare data with each other and they do it better than a super computer, more relentlessly than a pit-bull and they do not give up and do not surrender.

They are intense and even fanatical researchers with passion, drive, motivation, education and intelligence and they are going to change the entire stem cell industry from the inside out.  You can love them or hate them but do NOT get in their way.  They are blind to bureaucracy, oblivious to obstacles and dismissive of despair.  Their engines run on the nova hot burning jet fuel of a parent’s love for their child, they wield weapons built on research and science and wear impervious suits of armor forged in hope.

They are stem cell moms and they are organized and aggressive and nothing will stand in their way.

They are…

THE STEM CELL MOMFIA

wgun4

STEM CELLS COME TO THE USA!!!

In STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on April 23, 2013 at 9:00 am

usa-flag-grunge

 Stem Cells Come to the USA!

A real possibility is that all off shore facilities will go under shortly as people realize stem cells are coming to the USA.   Not only “the smart patient” but also “the smart investor” will return home.   Please forward to relevant parties and contact me if you want to know what the next step is to US based stem cell facilities and treatments.

DrugTrialsKUMedLeukemiaSociety-13-0-315-153 304

Brownback signs into law bill establishing adult stem cell research and treatment at KU Medical Center

Topeka — In a mix of science and anti-abortion politics, Gov. Sam Brownback on Monday signed into law a bill that establishes the nation’s first adult stem cell research and treatment center at the Kansas University Medical Center.

“I am honored to sign this bill of hope and promise and current treatments,” Brownback said.

Brownback described adult stem cell and umbilical cord blood research as an “exploding” area of new discoveries to treat people with a wide range of diseases. “KU will be the leader, Kansas will be the leader, which is fabulous in this burgeoning field,” he said.

But the bill carried political overtones.

It was sponsored by vehement abortion opponents and pushed by the Family Research Council, a conservative Christian lobbying group.

In addition, KU never asked for the legislation establishing what will be known as the Midwest Stem Cell Center, and the Legislature has yet to produce the estimated $1.1 million needed for the center’s startup.

Dr. Buddhadeb Dawn, director of the Division of Cardiovascular Diseases at KU Medical Center, on Monday speaks during Gov. Sam Brownback’s bill-signing ceremony on legislation establishing the Midwest Stem Adult Stem Cell Center.  The center will be charged with working on adult stem cell, cord blood and related stem cell research, providing therapies to patients and serving as a clearinghouse for physicians on cutting-edge treatments.  The center is prohibited from using embryonic stem cells or cells taken from aborted fetal tissue.  Abortion opponents oppose human embryonic stem cell research because it involves the destruction of the embryo.

Dr. Buddhadeb Dawn, director of the Division of Cardiovascular Diseases at KU Medical Center, was the only KU representative on hand at the bill-signing ceremony. He said the number of clinical trials of bone marrow stem cells for treatment of heart disease had been increasing tremendously over the past several years.

“It would be great to bring such therapies to Kansas, and the formation of such a center which would engage in adult stem cell therapy in patients would give Kansans the chance to be enrolled in such therapy and perhaps give treatment that would change their life,” he said.

David Prentice, senior fellow for life sciences at the Family Research Council, said the center “puts Kansas in a leadership position.”

State Sen. Mary Pilcher Cook, R-Shawnee, who carried the bill in the Legislature said she would push for funding the center when the Legislature returns May 8 for the wrap-up session.

“That’s all under discussion right now,” she said.

At the bill-signing ceremony, several people who have survived diseases spoke about their treatments and how they believed the new center would expand the availability of treatments for others.

Mary Rusco, of Wichita, said she received stem cells from an umbilical cord.

“I have been cancer free for four years now, and as far as I’m concerned I’m cured. I really appreciate the fact that Kansas is doing this so that other people can have access to this opportunity,” she said.

Terry Killman, of Independence, received a bone marrow transplant from his brother.

“This bill will make it that much better for more people to have the opportunity that I’ve had to live,” he said.

Summary of Senate Bill 199 ( .PDF )

UFC PRESIDENT DANA WHITE 100% AFTER STEM CELL TREATMENT

In STEM CELLS IN THE NEWS on April 19, 2013 at 4:43 pm

This is how it happens.  A-Rod says: yo, dude, them stem cells worked for me, try it out…then Dana White gets them and has “100% success!” and then Dana reaches out to Freddy Roach, boxing trainer extraordinaire all following Muhammad Ali who got them in 20010 and they’ll tell 2 friends and so on…and then it’s everywhere!  Damn right!  My 8 years of shouting from the rooftops have led to this moment in time.  Can I get an “Amen” and a “Tipping Point!”

Dana White Meniere’s Disease: A-Rod, German stem cell treatment cure UFC President ‘100 percent’

By Adam Guillen Jr. on Apr 18 2013, 7:00p  @AdamGuillenJr 54

A HISTORY OF STEM CELLS

AND HEARING DISORDERS

Scott Cunningham

On a tip from New York Yankees third basemen Alex Rodriguez, UFC President Dana White recently made a pitstop in Germany to undergo a stem cell procedure to alleviate his battle with Menier’s Disease. It apparently did more than just that …

Ultimate Fighting Championship (UFC) President Dana White revealed last year he was suffering from Menier’s disease, an inner ear disorder that causes spontaneous episodes of vertigo, which is a spinning sensation that also includes fluctuating hearing loss, as well as ringing in the ear (tinnitus), among other debilitating symptoms.

After a failed surgery (see graphic footage ere) to correct the ailment, which resulted in the Las Vegas, Nevada, mixed martial arts (MMA) boss suffering a “bad attack” during a recent trip to Ireland, White rolled the dice, opting to go the experimental route to alleviate the problem.

And he can thank New York Yankees third basemen, Alex Rodriguez, for the advice.

After a recent exchange with $275 million man, White flew out to Germany to undergo a stem cell procedure that miraculously has him now feeling like “a million bucks.” He recently shared the bizarre road to recovery on a recent appearance on “Jay Mohr Sports” on Fox Sports Radio.

His explanation:

“Well, A-Rod from the Yankees, hit me up and told me that when he was hurt Kobe called him and they both went to Germany and did this stem cell stuff. Right. So he says listen bro, I don’t know if this is going to help you, but I’ll tell you what it’s worth a shot. Well long story short, we had the fight out in Sweden. I went to Germany. I got the stem cells. Dude, I am 100 percent cured. I am 100 percent a new guy, man. I’m working out again. I’m doing all the things that I used to do. I’m traveling. My life is back. All they do is they go in there, they take your blood, they incubate it, they spin it and add stuff to it. I don’t know what the hell they do, I’m no scientist. I’m a million bucks now, man. I couldn’t feel better.”

According to White, the original procedure only made the problem worse, causing him to live a pretty “miserable life.”

But, thanks to German doctors, he’s a “new guy” and is now looking to pass on the knowledge to world-famous boxing trainer Freddie Roach, who suffers from Parkinson’s Disease, because the same stem cell procedure can help improve the nervous system.

Spread the word.

KIDNEY BREAKTHROUGH: COMPLETE LAB GROWN ORGAN WORKS IN RATS

In ALL ARTICLES, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on April 19, 2013 at 4:00 pm
A brand new rat kidney being built on the scaffold of an old one <i>(Image: Ott Lab, Center for Regenerative Medicine, Massachusetts General Hospital)</i>

A brand new rat kidney being built on the scaffold of an old one

(Image: Ott Lab, Center for Regenerative Medicine, Massachusetts General Hospital)

Kidney breakthrough: complete lab-grown organ works in rats

 

  • 18:00 14 April 2013 by Andy Coghlan

 

For the first time, complete lab-grown kidneys have been successfully transplanted into rats, filtering and discharging urine as a normal kidney would.

 

The breakthrough paves the way for human-scale versions, which could potentially provide an inexhaustible supply of organs, eliminating the need for recipients to wait for a matching donor kidney Movie Camera.

 

Similar techniques have already been applied successfully in people with simpler tissue, such as windpipes. But the kidney is by far the most complex organ successfully recreated.

 

“If this technology can be scaled to human-size grafts, patients suffering from renal failure, who are currently waiting for donor kidneys, could theoretically receive an organ grown on demand,” says Harald Ott, head of the team that developed the rat kidneys at the Massachusetts General Hospital in Boston.

 

“In an ideal world, such grafts could be produced from patient-derived cells, enabling us to overcome both donor organ shortages and the need for long-term immunosuppression drugs,” says Ott. Currently in the US alone, 18,000 transplants are carried out each year, but 100,000 Americans remain on waiting lists.

 

Strip and coat

 

To make the rat kidneys, Ott and his colleagues took kidneys from healthy “donor” rats and used a chemical solution to wash away the native cells, leaving behind the organ’s scaffold. Because this is made of collagen, a biologically inert material, there is no issue of the recipient’s body rejecting it.

 

Next, the team set about regrowing the “flesh” of the organ by coating the inner surfaces of the scaffold with new cells. In the case of humans, these would likely come from the recipient, so all the flesh would be their own.

 

The kidney was too complex to use the approach applied to the windpipe – in which its scaffold was coated by simply immersing it in a bath of the recipient’s cells.

 

Instead, the team placed the kidney scaffolds in glass chambers containing oxygen and nutrients, and attached tubes to the protruding ends of the renal artery, vein and ureter – through which urine normally exits the kidney. They recoated the insides of the blood vessels by flowing human stem cells through the tubes attached to the artery and vein. Through the ureter, they fed kidney cells from newborn rats, re-coating the labyrinthine tubules and ducts that make up the kidney’s urine filtration system.

 

It took many attempts to establish the precise pressures at which to feed the cells into the organ, as if it was growing in an embryonic rat. Remarkably, given the complexity of the kidney, the cells differentiated into exactly those required in the different compartments of the organ. “We found the correct cell types homed in to specific regions in the organ matrix,” says Ott.

 

The kidneys, which took about a fortnight to fully recoat, worked both in the lab and when transplanted into rats. They filtered out and discharged urine, although they did not sieve it as well as a natural kidney would. Ott is confident that the function can be improved by refining the technique.

 

Humans and pigs

 

The team is now attempting the same procedure using human kidneys, and also pig kidneys, which could be used to make scaffolds if there were a scarcity of human donors. The team has already successfully repopulated pig kidneys with human cells, but Ott says further studies are vital to guarantee that the pig components of the organ do not cause rejection when transplanted into humans.

 

The fact that heart valves and other “inert” tissues from pigs are already successfully used in humans without rejection suggests that this will not be a big problem.

 

Other researchers working in the field hailed the team’s success at recreating such a complex organ. “The researchers have taken a technique that most in the field thought would be impossible for complex organs such as the kidney, and have painstakingly developed a method to make it work,” says Jamie Davies at the University of Edinburgh, UK, who was part of a team that last year made some headway in their attempts to grow kidneys from scratch in the lab. “By showing that recellularisation is feasible even for complicated organs, their work will stimulate similar approaches to the engineering of other body systems.”

 

Journal reference: Nature Medicine, DOI: 10.1038/nm.3154

WHY NEW ATOMS AREN’T A FOUNTAIN OF YOUTH

In ALL ARTICLES, OFF THE BEATEN PATH on April 19, 2013 at 3:42 pm
Why New Atoms Aren’t a Fountain of Youth

by Shannon Fowler

July 14, 2007 2:58 PM
Photo of Atomic Model

Even though our atoms are replaced each year, the cells that carry the atoms eventually become damaged and stop working as efficiently.

Three Lions/Getty Images

If our atoms are being replaced every day, why do we age?

In a study published in the Annual Report for Smithsonian Institution in 1953, scientists found that 98 percent of our atoms are replaced each year. Atoms make up molecules, which make up cells, which make up tissues, which make up organs.

So with all these new atoms in our bodies every year, why do we get old?

Lawrence Brody, Ph.D., a physicist at the National Human Genome Research Institute, says the problem isn’t that the atoms are getting old, but that the structure is.

“Imagine building a sand castle. Four walls, some nice turrets, central spire, a moat—you gotta have a moat,” Dr. Brody says. “Now start replacing 100 percent of the sand with nice new sand.”

Think about what would happen to the structures of the walls and the turrets. How well would the moat continue to function after all that sand was replaced?

Carbon Copy

Every day, our bodies take in new atoms from the air we breathe, the food we eat, and the liquids we drink. These atoms are incorporated into our cells and fuel the chemical processes that keep us alive.

But our cells are constantly being regenerated. The DNA in each cell copies itself over and over again. Eventually, mistakes creep in and cells develop faults which get copied and passed on.

Suppose a chain mail goes out by fax — it goes to a friend, who faxes it to a friend, and so on. Over time, spots and wrinkles on the paper appear, and these turn up in subsequent copies.

Environmental Damage

Some cells, like red blood cells, white cells or skin cells, have short life spans of weeks to months. Because they replace themselves so often, there is a higher chance a copying mistake will arise.

Cells in our brains, heart, and bones last longer. Although these cells are less vulnerable to copying mistakes, they are more susceptible to damage caused by environmental factors such as radiation or toxins. Either way, cells stop working as well and we grow old.

Oxygen Damage

We need oxygen to survive. But during the normal chemical processes that take place in our bodies, oxygen can produce free radicals. These are highly unstable molecules that can set off chemical reactions that interfere with DNA and damage cells.

Free radicals are thought to play a key role in aging. So what can we do about oxygen?

“Avoid it, and you’d stay young forever,” Dr. Brody advises.

 

ATOMIC TUNE UP: HOW THE BODY REJUVENATES ITSELF

In ALL ARTICLES, OFF THE BEATEN PATH on April 19, 2013 at 3:40 pm
Atomic Tune-Up: How the Body Rejuvenates Itself

by

July 14, 2007 6:49 PM
Image of Star Trek actor DeForest Kelley

On Star Trek, Dr. Leonard McCoy, played by actor DeForest Kelley, never wanted to be beamed anywhere because he worried it would scatter his atoms across the universe.

Hulton Archive/Getty Images

For most people, a makeover means losing weight and getting new clothes, hair and makeup.

But what they may not know is that the body does its own extreme makeover regularly. In fact, 98 percent of the atoms in the body are replaced yearly.

Researchers in the 1950s made the discovery by feeding their subjects radioactive atoms. Using radiation detectors, the researchers watched the atoms move all over the body. They found that the new atoms replaced old ones and ended up in all tissues of the human body.

But these atomic makeovers prompt a more philosophical question: Are people really themselves if their atoms are always new, or are they new people each year? David Kestenbaum tackled that philosophical question — and discussed atomic makeovers — with the experts.

 

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