DAVID GRANOVSKY

Russians develop cirrhosis cure : Voice of Russia

In DISEASE INFO on September 16, 2011 at 8:10 am
Who better to do this than our Vodka drinking friends!
“This medicine mobilizes the stem cells not only in the liver but also in the marrow, which is the depot of stem cells. After taking the medicine, marrow stem cells enter into peripheral blood and then settle in the affected organ,” Gleb Zyuzkov said.

Russians develop cirrhosis cure

Sep 1, 2011 16:11 Moscow Time

Сirrhosis © Photo: ru.wikipedia.org

Russian pharmacologists have invented a medicine capable of curing cirrhosis, which has been considered incurable. There is no similar drug elsewhere in the world. At present, this is the most effective medicine to treat cirrhosis of which 40 million people die annually.

Until recently, medical science has lost in the fight against cirrhosis. This is a very serious illness and even if the patient survives, he or she will never be a healthy person because changes in liver tissues are irreversible in this case. However, Russian scientists in Siberia, who developed the medicine, have aroused hope in mankind. The new medicine is not only capable of recovering the suffered organ but also of preventing the pathology from developing further, says one of the developers, academic secretary at the Institute of Pharmacology, Gleb Zyuzkov.

“This medicine mobilizes the stem cells not only in the liver but also in the marrow, which is the depot of stem cells. After taking the medicine, marrow stem cells enter into peripheral blood and then settle in the affected organ,” Gleb Zyuzkov said.

There is no such medicine on the global pharmaceutical market although scientists across the world are working on the problem. This is logical because, according to the World Health Organization, the sickness rate of chronic hepatitis and cirrhosis has grown 8 times over 50 years. At present, liver diseases are on the fourth place in the rating of most fatal illnesses surpassing tuberculosis and ischemic attacks. The situation in Russia is complicated owing to the fact that a significant part of the population is addicted to alcohol. Although it’s incorrect to say that only drinking is capable of affecting the liver with cirrhosis. There are other reasons that lead to cirrhosis. Among these are hepatitis and illnesses in bile ducts and the long use of various medicines. Improper diet, air pollution and excessive use of household chemistry also seriously affect the liver.

Ten years ago, Americans said that they had developed a medicine against cirrhosis. They discovered a matter capable of blocking the RSK protein that launches the mechanism of cirrhosis. But this has side effects and scientists have failed to reduce its toxicity.

Last year, specialists in Britain grew a fragment of a liver in a test tube using stem cells collected from cord blood. Specialists believe that these fragments can be used to replace the affected sections of the organ. But this method is far from practical use like other methods in cell and gene therapy area.

According to Gleb Zyuzkov, the method suggested by the Siberian scientists is the most expedient physiological approach towards the resolution of tasks in regenerative medicine, precisely pharmacological strategy of cell therapy. The greatest advantage of the new method is that it has good prospects.

At present, under the federal special programme for promoting the pharmaceutical and medical industry, the invention by Siberian scientists is undergoing clinical tests. Specialists believe that the long awaited medicine, which has been named “life tablets”, will be available at pharmacies in five years.

Russians develop cirrhosis cure : Voice of Russia.

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