DAVID GRANOVSKY

Archive for March 31st, 2011|Daily archive page

ADULT STEM CELL voice box transplant trials could begin in 2013

In STEM CELLS IN THE NEWS on March 31, 2011 at 5:51 pm

Professor Birchall carried out the world’s first stem cell transplant of a windpipe in 2008.  Now he wants a clinical trial so he can help 1,300 patients a year with larynx problems. Well done sir!  – dg

Stem cell voice box transplant trials could begin in 2013

Speaking at the UK National Stem Cell Network annual science meeting today in York (30 March), Professor Martin Birchall will announce that the first clinical trials for stem cell voice transplants will begin in 2013, thanks to a million pounds provided by the Medical Research Council (MRC).

This revolutionary new kind of transplant treatment could change the lives of to 1300 patients a year in the UK who suffer serious problems with breathing, speaking and swallowing.

Loss of a working larynx (voice box) not only affects speech, swallowing, breathing, but also smell, taste, coughing, lifting and kissing, affecting thousands of people in the UK. Having carried out the world’s first stem cell transplant of a windpipe in 2008, Professor Birchall will be heading up a team to formally assess whether a similar approach can be used to repair problems in a voice box.

This research opens up new possibilities for patients receiving other kinds of transplants as well. One of the main problems currently facing those in need of donor organs is that they will need to take drugs for the rest of their lives as a result of the transplant. This new project, known as RegenVOX proposes that by using stem cells, this method could potentially help restore the patient’s own immune system and reduce the need for immuno-suppresant drugs.

Health News – Stem cell voice box transplant trials could begin in 2013.

How nasal stem cells might prevent childhood deafness

In VICTORIES & SUCCESS STORIES on March 31, 2011 at 12:35 pm
Australia is starting to catch up.  This procedure has been done in Asia, Europe and South America…just not in the USA or Australia. – dg
How nasal stem cells might prevent childhood deafness

Australian scientists have shown for the first time in mice that nasal stem cells injected into the inner ear have the potential to reverse or restore hearing during early onset sensorineural hearing loss.

Sensorineural hearing loss occurs when hearing cells in the cochlea lose their function. Frequently inherited, and usually starting during infancy and early childhood, the condition can slow a child’s development and lead to speech and language problems.

Drs Jeremy Sullivan, Sonali Pandit and Sharon Oleskevich from Sydney’s Garvan Institute of Medical Research, found that stem cells appear to release ‘factors’, or chemical substances, that help preserve the function of cochlear hearing cells, without the stem cells becoming part of the tissue of the inner ear. Their findings are published in STEM CELLS, now online.

“We are exploring the potential of stem cells to prevent or restore hearing loss in people,” said project leader Dr Sharon Oleskevich.

“The mice we are using have a very similar form of childhood deafness to their human counterparts – except, of course that mouse years are shorter. So a mouse will tend to lose their hearing within 3 months, where a person might take 8 years.”

“We are encouraged by our initial findings, because all the mice injected with stem cells showed improved hearing in comparison with those given a sham injection. Roughly half of the mice did very well indeed, although it is important to note that hearing was not completely restored to normal hearing levels.”

Adult human nasal stem cells were used in the procedure, because they are plentiful, easy to obtain and unspecialised (so have the ability to self-renew for long periods, as well as differentiate into cells with a variety of functions).

The same group of scientists has shown in previous publications that stem cells can also be used to improve hearing in noise-induced hearing loss – a condition that affects both young and older people.

It has taken 5 years to reach the current stage of research, and scientists anticipate that it will take a further decade at least for the findings to benefit people.

How nasal stem cells might prevent childhood deafness – insciences.

MENSTRUAL BLOOD STEM CELL BANKING IN INDIA

In STEM CELLS IN THE NEWS on March 31, 2011 at 10:24 am
Menstrual blood stem cell banking being launched in India

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New Delhi : Menstrual blood stem cells can now be easily collected, processed and harvested in an affordable, painless and non-invasive manner.

This unique stem cell banking is being launched in India for the first time at Chennai, capital of Tamil Nadu state, as LifeCell Femme menstrual blood stem cell banking service.

Until now, menstrual blood was discarded as unsanitary waste. Menstrual blood contains a large number of self-renewing stem cells that multiply rapidly and can differentiate into many other types of cells such as neural, cardiac, bone, fat, cartilage and possibly others, demonstrating great potential for cell therapy, statesman reported quoting the recent research.

Every month during a woman’s menstrual period the uterine lining, endometrium, is shed along with the extra blood and tissues. This lining of the uterus contains a large number of mesenchymal stem cells and several thousand fold high concentration of stem cell growth factors. These cells from the endometrium are unique because they have many properties and characteristics similar to both bone marrow and embryonic stem cells.

Although menstrual stem cell technology has not yet been utilised to date in human therapies, the collective body of ongoing research may potentially change the types of therapies used to diagnose or treat a host of significant medical conditions in the future affecting hundreds of millions worldwide like Alzheimer’s disease, atherosclerosis, diabetes, heart disease, inflammatory bowel disease, Parkinson’s disease, osteoarthritis, rheumatoid arthritis and many others.

“Stem cell technology is the future of medicine. Experiments performed at the Keio University school of medicine have succeeded in growing sheets of heart muscle from connective tissue cells harvested from menstrual blood When it comes to growing heart muscle, however, the connective tissue cells in menstrual blood have a success rate 100 times higher than the 0.2 – 0.3 percent for stem cells taken from human bone marrow,” said the chief scientific officer, LifeCell International, Dr Ajit Kumar.

Once collected the menstrual blood stem cells are dispatched to LifeCell’s state of the art laboratory facility at Chennai for processing. The stem cells are then harvested and the menstrual stem cells are frozen in liquid nitrogen storage container for cryogenic preservation at sub-zero minus 196 degrees centigrade. This procedure will enable the stem cells to retain their potency and viability for an indefinite period of time.

Menstrual blood stem cell banking being launched in India | TwoCircles.net.

How to Donate Menstrual Blood for Stem Cell Research

By an eHow Contributor

The use of menstrual blood as a resource for stem cells has been an interesting development in the field of bioresearch. The idea of collecting stem cells has been a controversial one at times. With this new method, there is no moral dilemma for anyone involved. In the future, people will benefit from the open availability of these types of stem cells. Currently, one company has the market cornered in the collection and storage of menstrual blood for stem cells. The company is called C’Elle. Collecting and storing your menstrual blood for its stem cells is easy.

Instructions-things you’ll need:

  • Collection package
    • 1

      Order your collection kit from C’Elle through their company website (see Resources).

    • 2

      Freeze the cooling packs that arrive with your C’Elle collection kit immediately upon arrival and continuously until you are ready to package your collections and send them back via FedEx.

    • 3

      To collect your menstrual blood, insert the provided menstrual cup in place of a tampon. This cup needs to be left in for three hours to collect your first of two specimens.

    • 4

      Take the menstrual cup out. It should have about a teaspoon of fluid in it. Carefully place this fluid into the provided vials of solution.

    • 5

      Refrigerate your first specimen while you collect your second.

    • 6

      Replace your menstrual cup for another three hours and repeat the collection process for your second vial. One vial will be used for storage and the other will be used for infectious disease testing.

    • 7

      Remove your cooling packs from the freezer; the first specimen from the refrigerator and package both specimens and the cooling packs in your original collection kit box after you have collected both specimens.

    • 8

      Ship your collection kit back to C’Elle using the provided airbilled FedEx box.

Read more: How to Donate Menstrual Blood for Stem Cell Research | eHow.com http://www.ehow.com/how_4587255_menstrual-blood-stem-cell-research.html#ixzz1Ia5iwhot

Stem Cell Technology Treating Many Degenerative Diseases…In Pets

In ALL ARTICLES on March 31, 2011 at 10:14 am

Technology is giving us many new inventions daily. One such recent invention of world class manufacturing technology has been made by Medivet Pty Ltd. The Research and Development Division of the company has introduced a new procedure with the help of which, the veterinarians can extract, process and activate an animal’s own adult stem cells by injecting them back again into the animal’s own body.

Medivet has recently introduced this unique procedure. Several countries worldwide and many international veterinarians today are using this procedure to treat many degenerative diseases such as primary and secondary arthritis, hip dysplasia, damaged or torn ligaments and tendons, joint pain, worn or damaged cartilage etc.

Medivet has spent many years and millions of dollars to introduce this one of the most exciting and valuable treatments ever released, exclusively for the veterinary field. The company is really making big with its American division, Medivet America LLC that is leading the field in sales and Adipose Stem Cell procedures.

Trials are still being conducted at many universities, in Australia and internationally. Also, thousands of Adipose Stem Cell Kits have been supplied to veterinarians enabling them to perform Stem cell procedures including the 14 international countries to which, Medivet is currently exporting the kits.

Stem Cell Technology Treating Many Degenerative Diseases Today | TopNews United States.

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