DAVID GRANOVSKY

Autism recreated from stem cells in lab study

In VICTORIES & SUCCESS STORIES on February 14, 2011 at 3:54 pm

INDUCED PLURIPOTENT STEM CELLS (IPSC) are not the stem cells we usually hear about because they are human skin cells (typically) that are regressed to an embryonic state.  The problem with the is that they carry the genetic abnormalities of the donor and they form cysts and tumors like embryonic stem cells.  SO they are useless for treating diseases until these problems are resolved.  Or are they?  Scientists have used IPSC to grow cells with Autism.  They can now follow the path of the disease  almost from embryo to fully mature cells and will learn a lot more about it. – dg

autism-ribbon

“Their findings, published in the Nov. 12, 2010, issue of Cell, revealed disease-specific cellular defects, such as fewer functional connections between Rett neurons, and demonstrated that these symptoms are reversible, raising the hope that, one day, autism maybe turn into a treatable condition.

“Mental disease and particularly autism still carry the stigma of bad parenting,” says lead author Alysson Muotri, Ph.D., an assistant professor in the Department of Molecular and Cellular Medicine at the University of California, San Diego School of Medicine.

“We show very clearly that autism is a biological disease that is caused by a developmental defect directly affecting brain cells.”

Stem cell research news: Autism recreated from stem cells in lab study – Gilbert Special Needs Kids | Examiner.com.

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