Discovery Aims to Correct Cellular Defects Leading to Diabetes
ScienceDaily (Jan. 4, 2010) — A new research discovery published online in the FASEB Journal may change the perception and treatment of diabetes. That’s because scientists have moved closer toward correcting the root cause of the disease rather than managing its symptoms. Specifically researchers identified a protein (G6PD protein) and its antioxidant product (NAPDH) that both prevent the death and promote the growth of cells which produce and release insulin in the pancreas (beta cells).
“Abnormally high levels of oxidants are thought to be a major cause of diabetes and the complications of diabetes, as well as many other diseases,” said Robert C. Stanton, M.D., co-author of the study, from Joslin Diabetes Center in Boston. “By understanding the specific defects in processes that either produce too many oxidants or not enough antioxidants, a new era of highly specific, targeted treatments will emerge that very effectively treat or possibly prevent many of these diseases.”