DAVID GRANOVSKY

CATCH UP!! – US Cardiac Stem Cell Trial is years behind

In CATCH UP! on October 5, 2009 at 11:16 pm

https://i1.wp.com/www.nlm.nih.gov/medlineplus/ency/images/ency/fullsize/1097.jpg

“UCSF Medical Center (has)begun enrollment for an early-stage clinical trial…(using) adult stem cell therapy for patients who have just experienced their first acute myocardial infarction, or heart attack.”

THIS IS YEARS BEHIND!! HERE’S WHY:

“First came a year or two of (repair stem cell/cardiac) animal tests, then, in Paris, 2000, doctors gave a dying 70-year-old heart patient bone marrow cells and he lived four years, at which time the doctors ‘fessed up and released his name.

In 2001, USA pioneer Warren Sherman, MD (Columbia U, Mt. Sinai NY Hosp) went to Rotterdam and became the first American to implant ASC into a human heart. However, if you can believe it, the same Sherman, calls those that have taken forward what he did eight years ago, “snake oil salesmen.”

In 2002, a very daring clinical trial led by Dr. Hans Dohmann plus six colleagues in Brazil took 21 transplant candidates and gave 14 of them bone marrow cells. The results were so spectacular that the AHA accepted the paper and it was presented in 2003. Five of the seven in the control group opted in to make a total of 19 stem cell transplants. The mortality rate for transplant candidates is about 35% per year. At that rate there would be, of those 19, only 2.2 patients still alive after five years. There were, in fact, 12 alive as of Dec. 31, 2007; more than five years down the road.

In 2003, Dr. Andreas Zeiher of the Goethe Institute in Frankfurt began much larger trials. As of 2007, he has overseen more ASC implants into hearts than anyone, both in and out of clinical trials.

In 2004, Dr. Amit Patel of Pittsburgh completed two of the most successful trials ever, especially when, in Uruguay, he proved, on a group of ischemic heart failure patients, that a bypass plus cells was infinitely better than a bypass only. That same year, TheraVitae, in Israel, developed a new, powerful blood-derived stem cell and dared to treat the sickest patients no clinical trial would consider.

Also in 2004, one of the Brazilians, Dr. Perin, came to Texas and used the Brazil results to get the first ASC heart clinical trial approved by the FDA. Over a dozen such approvals were granted in the next 12-18 months.

Meanwhile, around the world, while USA stem cell research remains mired in politics instead of science, ASC advances in virtually every sector of medicine are rocketing forward without any sign of letting up.

In 2005, Drs. Vina & Saslavsky in Argentina completed the very first successful diabetes2 stem cell clinical trial in the world: 13 out of 16 successfully cured. Spinal problems and emphysema and renal failure and cirrhosis of the liver treatments will be moving to the forefront in 2008-9. (Yes, but mostly in China and elsewhere, while Americans die with those diseases without a chance of help from their “doctors.”

AND MORE:

More info on heart disease and stem cells treatment: https://repairstemcell.wordpress.com/2009/09/24/heart-disease-asc-a-brief-history/

Patients are being treated all over the world today with years of research and clinical trials behind the procedures.

Excerpt from the original YEARS BEHIND article:

Cardiac Stem Cell Trial Seeks To Treat Some Heart Attack Patients

Monday, October 05, 2009

Researchers at UCSF Medical Center have begun enrollment for an early-stage clinical trial to evaluate the safety and efficacy of an adult stem cell therapy for patients who have just experienced their first acute myocardial infarction, or heart attack. The trial is part of a multi-center national study.

The cells used, known as mesenchymal stem cells, were obtained from the bone marrow of healthy adult donors. Depending on their location in the body, mesenchymal stem cells give rise to bone, cartilage, fat, muscle and connective tissue.

The experimental therapy is intended to combat the symptoms related to heart damage that continue to develop following a heart attack, including low pumping capacity, inflammation and increased scar tissue.

via Cardiac Stem Cell Trial Seeks To Treat Some Heart Attack Patients – The Philadelphia Bulletin.

 

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