DAVID GRANOVSKY

Archive for September 8th, 2009|Daily archive page

The ADA is Confused about Embryonic Stem Cell Potential

In ALL ARTICLES on September 8, 2009 at 10:51 pm

The ADA (American Diabetes Association) has influence over their 70,000 members, the 350,000 people who contacted them over the past year and the nearly 24 million children and adults in the U.S. with diabetes their advocacy efforts support…

That is why it is so sad to see them placing all of their hope on embryonic stem cell research.
Excerpted from the original article:
“The Stem Cell Research Enhancement Act, also known as H.R.3… would ease up on the existing restrictions on embryonic stem cell research… The American Diabetes Association knows that the passing of this act is the best hope humans have for advancement in the cure for Diabetes.”

Here is a only a small collection of articles that show that ADULT stem cells are the REAL and CURRENT and BEST hope humans have for advancement in the cure for Diabetes.

Stem Cells + Hyperbaric Improve Diabetes type 2 - http://wp.me/prcQV-1dc

Insulin-Producing Cells From Adult Skin Cells – http://wp.me/prcQV-1da

Can stem cells cure Diabetes – type 2? – http://wp.me/prcQV-1cU

Can stem cells cure Diabetes – type 1? - http://wp.me/prcQV-1cJ

…………………
To read the original article:

Stem Cell Research Enhancement Act Relating to Diabetes.

HUGE STEP – earlier testing + better treatment for Alzheimer’s

In ALL ARTICLES on September 8, 2009 at 10:23 pm

Alzheimer’s research links three genes to disease – The Guardian 7th September 2009

Findings hailed as ‘huge step’ towards earlier testing and better treatment for Alzheimer’s

tags: Genetics, Alzheimers Disease, Health, News, Diagnosis, Drug Therapy, UHN, The Guardian

Additional Story

  1. Genetic breakthrough brings cure for Alzheimer’s a step closer – The Times 7th September 2009
  2. British scientists make giant leap in battle against Alzheimer – Daily Mail 7th September 2009
  3. Alzheimer’s genes link uncovered – BBC Health News 6th September 2009

‘Bionic’ Nerve To Bring Damaged Limbs + Organs Back To Life

In VICTORIES & SUCCESS STORIES on September 8, 2009 at 10:13 pm

‘Bionic’ Nerve To Bring Damaged Limbs And Organs Back To Life (Oct. 18, 2007) — University of Manchester researchers have transformed fat tissue stem cells into nerve cells — and now plan to develop an artificial nerve that will bring damaged limbs and organs back to life. In a … > read more

via Injectable Biomaterial Regenerates Brain Tissue In Traumatic Injuries.

Stem cells exploitation for Pediatric Surgery

In STEM CELLS IN THE NEWS on September 8, 2009 at 10:08 pm

ES, iPS, MSC, and AFS cells.

Stem cells exploitation for Pediatric Surgery: current research and perspective

Journal Pediatric Surgery International

Publisher Springer Berlin / Heidelberg

ISSN 0179-0358 (Print) 1437-9813 (Online) – DOI 10.1007/s00383-009-2478-8

SpringerLink Date Thursday, September 03, 2009

ES, iPS, MSC, and AFS cells. Stem cells exploitation for Pediatric Surgery: current research and perspective

Michela Pozzobon1, Marco Ghionzoli2 and Paolo De Coppi2 Contact Information

(1) Stem Cell Processing Laboratory, Department of Pediatrics, University of Padova, Padova, Italy

(2) Surgery Unit, UCL Institute of Child Health & Great Ormond St Hospital, 30 Guilford Street, London, WC1N 1EH, UK

Accepted: 18 August 2009 Published online: 1 September 2009

Abstract Despite the advancements that have been made in treating infants with congenital malformations, these still represent a major cause of disease and death during the first years of life and childhood. Regeneration of natural tissue from living cells to restore damaged tissues and organs is the main purpose of regenerative medicine. This relatively new field has emerged by the combination of tissue engineering and stem cell transplantation as a possible strategy for the replacement of damaged organs or tissues. This review would like to offer an insight on the latest evolution of stem cells with a glance at their possible application for regenerative medicine, particularly in the Paediatric Surgery field.

Keywords Stem cells – Regenerative medicine – ES – iPS – MSC – AFS cells – Pediatric Surgery

via SpringerLink – Journal Article.

Gallbladder removed through vagina

In ALL ARTICLES on September 8, 2009 at 8:01 pm

While Dr Oz is trying to save lives without using his scalpel – https://repairstemcell.wordpress.com/2009/09/08/dr-oz-wants-to-save-lives-without-using-scalpel/ - other surgeons are trying to make removing organs a wHOLE lot easier…so tell me…

Would you rather have your life saved using

NO SCALPEL?

Or would you rather have your life saved by having your

appendix pulled out through your mouth

or your

gallbladder removed through your vagina?


Body has Holes; Can Surgeons Use Them?

Omaha World-Herald February 13, 2009 http://www.omaha.com/index.php?u_page=1219&u_sid=10562747

An appendix pulled out through the mouth. A gallbladder removed through the vagina. It almost sounds bizarre. But surgeons at a handful of medical centers across the country are performing these experimental procedures. This type of surgery, which involves removing organs through natural body openings, could be available locally if a Nebraska Medical Center surgeon succeeds in making a device to improve the procedure…

Dr. Nathaniel Soper, chairman of the surgery department at NORTHWESTERN University, said no major complications have been reported in the United States from the surgery. He has performed it himself and said a study beginning within the next year will compare it with laparoscopic surgery to assess risks and benefits…

http://www.omaha.com/index.php?u_page=1219&u_sid=10562747

Dr. Oz wants to save lives without using scalpel

In CELEBRITIES & STEM CELLS on September 8, 2009 at 1:43 pm

Article ImageOz had a decent enough career before television beckoned. He’s a prominent surgeon with expertise in repairing heart valves. He will continue to perform surgery one day a week.

Yet Oz noticed that he was getting more jazzed up persuading people they didn’t need surgery than operating on them.

He landed a show, “Second Opinion,” on the Discovery Channel and persuaded Winfrey to appear. That opened the door to Winfrey’s media kingdom, resulting in 55 appearances on her talk show in five years, and eventually his own show. It’s co-produced by Winfrey’s Harpo Productions and Sony Pictures Television. He’s contractually prohibited from airing in direct competition with her.

“I found myself going to work and taking care of people who wanted to get better who believed that their only path to salvation was through my scalpel,” he said. “I can heal with steel. I know how to do that. But it’s very disenfranchising when you realize the true solutions are outside the operating room.”

via Omaha.com – The Omaha World-Herald: Living – Dr. Oz wants to save lives without using scalpel.

Korean University To Distribute Puppies Of World’s First Cloned Dog

In STEM CELLS IN THE NEWS on September 8, 2009 at 1:28 pm

Korean University To Distribute Puppies Of World’s First Cloned Dog

Yes, we know, this is not the type of story we usually follow. The truth? It is apparently a first even if, in itself, the event does not advance the cause of stem cell research. Seoul National University (SNU) said the nine dogs were all fathered by Snuppy, an Afghan Hound cloned by disgraced scientist Hwang Woo-suk in 2005, who, as it turns out, may have gotten some important things right without knowing it. According to a team led by George Daley at Harvard Stem Cell Institute, Hwang may have managed to create stem cells solely from human eggs, without fertilization with sperm. This breakthrough is possibly much more valuable than his original false claims about his work.

“Unfortunately,” said Daley, “at the time they published their work they did not know what they had done so they had mistakenly isolated these parthenogenic embryonic stem cells and misrepresented them as true clones.” The Daley team concluded that it is possible Hwang and his team managed to pull off the world’s first human case of parthenogenesis, or ‘virgin birth’, a conclusion that would seem to suggest that even with good research it’s preferable to know the meaning of what has been accomplished.

via Stem Cell Research: Korean University To Distribute Puppies Of World’s First Cloned Dog.

Scientists grow fully functional tooth from stem cells

In VICTORIES & SUCCESS STORIES on September 8, 2009 at 1:18 pm

Scientists grow fully functional tooth from stem cells

August 22, 4:12 PMNY Holistic Body & Spirit ExaminerTima Vlasto

Though teeth have been grown in mice before, scientists revealed in the Proceedings of the National Academy of Sciences their success at growing a “fully functional” tooth from stem cells in mice.

The article states:

“Here, we report a successful fully functioning tooth replacement in an adult mouse achieved through the transplantation of bioengineered tooth germ into the alveolar bone in the lost tooth region. We propose this technology as a model for future organ replacement therapies. The bioengineered tooth, which was erupted and occluded, had the correct tooth structure, hardness of mineralized tissues for mastication, and response to noxious stimulations such as mechanical stress and pain in cooperation with other oral and maxillofacial tissues. This study represents a substantial advance and emphasizes the potential for bioengineered organ replacement in future regenerative therapies.”

The process is described in a paper titled “The development of a bioengineered organ germ method” in the journal Nature Methods by researchers with the Department of Biological Science and Technology at the Tokyo University of Science.

via Scientists grow fully functional tooth from stem cells.

Final step of pluripotency pinpointed!

In STEM CELLS IN THE NEWS on September 8, 2009 at 1:16 pm

Switching on the power of stem cells

21 August 2009

Scientists have uncovered a vital link in the chain of events that gives stem cells their remarkable properties.

Researchers from the Wellcome Trust Centre for Stem Cell Research at the University of Cambridge have pinpointed the final step in a complex process that gives embryonic stem cells their unique ability to develop into any of the different types of cells in the body (from liver cells to skin cells). Their findings, published today in the journal Cell, have important implications for efforts to harness the power of stem cells for medical applications.

via University of Cambridge.

The latest stories from “Adult Stem Cell Awareness”

In STEM CELLS IN THE NEWS on September 8, 2009 at 1:09 pm
The latest stories from “Adult Stem Cell Awareness”

Still No Human Trials for ESCR!

from Adult Stem Cell Awareness by chelseaz

Earlier this year the drug developer Geron Corp. announced that it was given FDA approval to begin the first trial of an embryonic stem cell treatment in humans. But alas, the FDA reversed its decision last week:

Geron said the Food and Drug Administration is reviewing new data from studies of the therapy, called GRNOPC1, on animals. The company plans to start testing its product on humans this summer, but that testing will be delayed during the FDA’s review. Geron said it will work with the FDA, and did not estimate how long the review will take.

This is significant given that most people think that ESCs have already been used to treat human patients. Meanwhile, ethical stem cells continue to kick butt and outperform – in animals as well as many humans. Full speed ahead!

Mesenchymal Stem Cells May Repair Damaged Brain Cells

from Adult Stem Cell Awareness by chelseaz

brainSomeone should tell Michael J. Fox:

There is no known cure for neurodegenerative diseases such as Huntington’s, Alzheimer’s and Parkinson’s. But new hope, in the form of stem cells created from the patient’s own bone marrow, can be found ― and literally seen ― in laboratories at Tel Aviv University.

Dr. Yoram Cohen of TAU’s School of Chemistry has recently proven the viability of these innovative stem cells, called mesenchymal stem cells, using in-vivo MRI. Dr. Cohen has been able to track their progress within the brain, and initial studies indicate they can identify unhealthy or damaged tissues, migrate to them, and potentially repair or halt cell degeneration. His findings have been reported in the journal Stem Cells.

“By monitoring the motion of these cells, you get information about how viable they are, and how they can benefit the tissue,” he explains. “We have been able to prove that these stem cells travel within the brain, and only travel where they are needed. They read the chemical signalling of the tissue, which indicate areas of stress. And then they go and try to repair the situation.”…

Dr. Cohen and his team of researchers took magnetic iron oxide nanoparticles and used them to label the stem cells they tested. When injected into the brain, they could then be identified as clear black dots on an MRI picture. The stem cells were then injected into the brain of an animal that had an experimental model of Huntington’s disease. These animals suffer from a similar neuropathology as the one seen in human Huntington’s patients, and therefore serve as research tool for the disease.

On MRI, it was possible to watch the stem cells migrating towards the diseased area of the brain. “Cells that go toward a certain position that needs to be rescued are the best indirect proof that they are live and viable,” explains Dr. Cohen. “If they can migrate towards the target, they are alive and can read chemical signalling.”…

Although there is a drawback to using this particular type of stem cell ― the higher degree of difficulty involved in rendering them “neuron-like” ― the benefits are numerous. “Bone marrow-derived MSCs bypass ethical and production complications,” says Dr. Cohen, “and in the long run, the cells are less likely to be rejected because they come from the patients themselves. This means you don’t need immunosuppressant therapy.”

Vatican Radio Discusses ASCR

from Adult Stem Cell Awareness by chelseaz

From Religious Intelligence:

Dr Settimio Grimaldi, an expert at the Institute of Neurobiology and Molecular Medicine in Rome, asked Vatican Radio listeners this week “Why we should complicate things by going and taking embryonic cells, with all the ethical questions that follow?”

The Vatican radio show discussed the latest developments in adult stem cell research which have revealed a method to repair a damaged heart by cultivating cardiac stem cells and re-injecting them to replace damaged tissue. Researchers revealed that the treatment could be available within three years following successful testing.

Dr. Grimaldi said: “The adult stem cell is already prepared to differentiate in the tissue we want to repair. And it is certainly more productive, less wasteful and less dangerous, beyond the ethical aspects, to work with adult stem cells instead of embryonic stem cells.”

Bone Marrow Stem Cell Treatment Saves Legs

from Adult Stem Cell Awareness by chelseaz

The results of a clinical trial to save volunteers’ leg from amputation by injecting stem cell concentrate to the limb affected by thrombo angitis obliterance (TAO) have been encouraging. The stem cells were taken from the patients’ bone marrow.

The clinical trial is being conducted on patients suffering from blocks in the artery of the leg. Sixty patients were enrolled in the trial, and all of them were smokers. Some had diabetes as well.

Thirty nine of the 44 patients who had already undergone the mandatory 6-month follow-up did not require amputation following stem cell injection to the affected legs. Follow-up of the remaining 16 patients is under way.

The last patient, enrolled on May 25, will complete his six-month follow up in November.

“We have got very good results,” said Dr. K.S. Vijayaragavan. “The legs of 89 per cent of the patients have been saved.” Dr. Vijayaragavan, Head of the Department of Vascular Surgery, Sri Ramachandra University, Chennai, is conducting the trial.

According to him, the failure to save the leg of five patients was because they continued to smoke even after stem cell injection. Immediate and complete cessation of smoking is the most basic and important requirement for saving the leg. Diabetes should also be under control.

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