Stem Cell Research Uncovers Mechanism for Type 2 Diabetes
Published on 12 February 2009, 14:33 Last Update: 17 minute(s) ago by Insciences
Tags: Stem Cell Diabetes Medicine Progenitor cells
LA JOLLA, Calif., February 12, 2009—Taking clues from their stem cell research, investigators at the University of California San Diego (UC San Diego) and Burnham Institute for Medical Research (Burnham) have discovered that a signaling pathway involved in normal pancreatic development is also associated with type 2 diabetes. Their findings, published online January 9 in Experimental Diabetes Research, could provide a potential new target for therapy.
Pamela Itkin-Ansari, Ph.D., assistant adjunct professor at the UC San Diego School of Medicine and Burnham; Fred Levine, M.D., Ph.D., professor and director of the Sanford Children’s Health Research Center at Burnham, and colleagues showed that the Wnt signaling pathway is up-regulated in insulin producing cells of pancreases from adults with type 2 diabetes…