DAVID GRANOVSKY

Posts Tagged ‘TREAT’

LATE STAGE OVARIAN CANCER CURED WITH STEM CELLS

In ALL ARTICLES, SCIENCE & STEM CELLS, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on July 7, 2014 at 1:03 pm

ovarian-cancer-symptoms
Hue Hospital Succeeds in Treating Cancer with Stem Cell

Saigon – Doctors of Hue Central Hospital have used stem cell transplantation to successfully treat a cancer patient of the last stage. The Hue Central Hospital announced on June 26 that its doctors have cured Le Thi Sau, 52, who was suffering ovarian cancer in the last stage, with stem cell transplant. The operation is the success of the scientific project “Using stem cell in breast cancer and cervical cancer” managed by Professor Nguyen Duy Thang, deputy head of the hospital. Adult stem cells have been used to treat certain cancers through bone marrow transplants. In this therapy, the stem cells that give rise to the different blood cells in the body are transplanted into the bone marrow of the patient, where they regenerate the blood. The project was given green light to carry out in the Hue Central Hospital by the Ministry of Science and Technology. Professor Nguyen Duy Thang said the success of this method will pave the way for next operations on breast and ovarian cancer patients. In the time ahead, the hospital continues to treat two other cancer female patients with the stem cell treatment. It is hoped that the treatment will save many cancer patients. (www.saigon-gpdaily.com.vn June 27)

WHAT DOES THE FOXO1 SAY? HERE’S MORE INSULIN!

In ALL ARTICLES, BUSINESS OF STEM CELLS on July 5, 2014 at 10:20 am
It May Take Guts to Cure Diabetes -Human GI Cells Retrained to Produce Insulin

Imagine taking cells from your gastrointestinal tract and then switching off one gene, the FOXO1 gene, and then ending up with insulin producing cells.  From gut cell to diabetes fighter in one easy gene switch-off.  Scientists did this successfully in 2012 in mice and recently in humans.  What does the FOXO1 say? ‘Here’s more insulin!’  Awesome.

The next step is where it gets…awkward.  I’d like this information to generate a gene therapy protocol or to improve success rates in stem cell/Diabetes treatment protocols,  etc.  But that’s not the way our system works.  The next step is to find a drug that inhibits the FOXO1 gene so it “…could retrain cells inside a person’s GI tract to produce insulin…”  Unfortunately, this drug will also have side effects as all drugs do which will create other symptoms requiring other drugs to mitigate.  And so it goes.

When will US Diabetes patients be able to benefit from a medical protocol based on this discovery?  An educated guess puts it at:
7-10 years for clinical trials and drug development for a name brand Pharma product and then 10-15 years for the drug patent to open up to an affordable generic.
Sorry Diabetes patients.

New York, NY (June 30, 2014) “By switching off a single gene, scientists at Columbia University’s Naomi Berrie Diabetes Center have converted human gastrointestinal cells into insulin-producing cells, demonstrating in principle that a drug could retrain cells inside a person’s GI tract to produce insulin…The Columbia researchers were able to teach human gut cells to make insulin in response to physiological circumstances by deactivating the cells’ FOXO1 gene.”

DO ADULT STEM CELLS CAUSE CANCER?

In ALL ARTICLES, SCIENCE & STEM CELLS, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on July 1, 2014 at 4:31 pm

NO!

cancer-free-zone

What do you get when you add 1,100 ADULT STEM CELL PATIENTS studied over 5 years,

plus another 1,873 ADULT STEM CELL PATIENTS studied over an average 12.5 years,

plus another ~7,000 ADULT STEM CELL PATIENTS in studies and FDA clinical trials data?

~10,000 ADULT STEM CELL TREATMENT PATIENTS showing NO CANCER!

 

“A total of 1873 patients were treated from 1990 to 2006 with bone marrow-derived concentrated cells. Patients were monitored for cancer incidence from the date of the first operation (1990) until death, or until December 31, 2011. The mean follow-up time was 12.5 years (range, five to twenty-two years)…No tumor formation was found at the treatment sites on the 7306 magnetic resonance images and 52,430 radiographs among the 1873 patients…This study found no increased cancer risk in patients after application of autologous cell-based therapy using bone marrow-derived stromal progenitor cells either at the treatment site or elsewhere in the patients after an average follow-up period of 12.5 years.

The upshot? This most recent study, as well as others, FDA clinical trials data, and the data we have published now amounts to about 10,000 patients who have been treated with adult stem cells and extensively tracked for this issue. There is no evidence that adult stem cells cause cancer. There is no rational reason for the fear, other than a completely different type of cell (ESC) that happens to have a similar name (stem cell) can cause teratomas – hence the confusion!”

Tumors, cancers and teratomas may result from Embryonic stem cell (ESC) treatments or Induced Pluripotent stem cell (iPSC) treatments

but NOT FROM ADULT STEM CELL TREATMENTS.

Sources:

PANCREATIC CANCER TUMORS DEFEATED WITH CORD BLOOD STEM CELLS

In ALL ARTICLES, SCIENCE & STEM CELLS, VICTORIES & SUCCESS STORIES on June 25, 2014 at 11:42 am

fight pancreatic cancer FPC_shirt


PANCREATIC CANCER TUMORS DEFEATED WITH CORD BLOOD STEM CELLS

What happens when you “genetically engineer MSCs isolated from human umbilical cord blood so that they expressed IL-15” (which fights cancer tumors) and inject them into mice with pancreatic  tumors?

  • The IL-15 migrate to the tumor
  • Other cancer and tumor fighting immune cells migrate to the tumor
  • The IL-15 attack the tumor
  • Other cancer and tumor fighting immune cells attack the tumor
  • Tumors show cell death
  • Tumor growth is significantly inhibited
  • Survival is prolonged
  • The mice immune systems are effectively vaccinated against future tumor growth

Scientists “used these souped-up cells to treat In mice afflicted with pancreatic tumors. Pancreatic cancer is an indiscriminate killer, since by the time it causes any symptoms, it is usually so advanced, that there is little to be done in order to treat it. Thus new strategies to treat this type of cancer are eagerly being sought. Systemic administration of IL-15-expressing MSCs significantly inhibited tumor growth and prolonged the survival of tumor-bearing mice. The tumors of these mice showed extensive cell death, and other types of immune cells known to fight tumor cells (NK and T cells) had also accumulated around the tumor. Other experiments confirmed that the injected MSCs did indeed migrate toward the tumors and secrete IL-15 at the site of the tumors…Interestingly, those mice that were cured from the pancreatic tumors, appeared to have a kind of resistance of these tumors. Namely, when Fan and his colleagues tried to reintroduce the same tumor cells back into the cured mice, the tumor cells would not grow. Thus the engineered MSCs not only tuned the immune system against the tumor, but they effectively vaccinated the mice against it as well.”

via http://beyondthedish.wordpress.com/2014/06/23/engineered-stem-cels-from-human-umbilical-cord-blood-eradicates-pancreatic-tumor/

 

 

Thanks Squeeky!

mouse-grown-from-stem-cells

REDUCING STEM CELL MIGRATION/ADHD TO FOCUS HEALING

In ALL ARTICLES, BUSINESS OF STEM CELLS, SCIENCE & STEM CELLS on June 23, 2014 at 2:55 pm

broken-bone-cast

REDUCING STEM CELL MIGRATION/ADHD TO FOCUS HEALING
“Stem cells are smart and will only stay in one place to repair damaged cells and tissues until called away for more dire situations requiring attention.  Like little ADHD multi-tasking mechanics/repairmen, they run all over the body where the body has decided (through a very complex set of devices) they are most needed.  This results in stem cells dedicated to mending bones, suddenly running off to fix the heart, pancreas, etc before finishing the job on the broken bone.  While this is a great holistic and triage approach (paying attention and dedicating resources to that which needs it most), it makes it difficult to access how powerful and successful stem cells are at resolving a single issue/condition in the body.

A lot can be said for repairing many areas in the entire body simultaneously, in fact, this is one of stem cells’ greatest strengths…but it doesn’t sit well with the concept of “completing one job before moving on to another.”  Scientists have devised a new way to make stem cells stay put and finish the job they were directed to do.  No more stem cell ADHD.

keep-calm-and-oh-look-a-squirrel-1

In the case of serious and terminal diseases, this is an excellent innovation.  If you can fix that which is going to fail first, you can then move on to what’s next.  It also makes commercialization of stem cells easier.  Nobody picks up their car with the damaged exhaust from the mechanic and he says: ‘I got the exhaust half done but realized your distributor, struts and alternator were shot so I fixed them instead.’  But your body is not a car.

This may be a wonderful innovation or it may be another instance of scientists trying to aggressively control a natural healing system in the body.  I think it’s both and the result is we now have one more extraordinary tool for fighting disease…and like any tool, it will be used well and for the right reasons and results and also used poorly for the wrong reasons and results.  Ultimately, our understanding of the modus operandi of stem cells has increased, our ability to manipulate stem cells has increased and the everyday miracles of stem cell treatment results are getting better and better understood and more common place all the time.” – David Granovsky

 ——————-

Delivering Capsules of Stem Cells Helps Repair Injured Bones

“One trouble with stem cells is that they don’t stay put. When doctors put cardiovascular progenitor cells in the heart to heal damage from a heart attack, the cells are whisked away in the bloodstream in a matter of hours.

Researchers, and a couple of renegade doctors in Colorado, have shown that stem cells do help bones heal. While bones, even the intricately shaped jawbone, have been grown in the lab, researchers have been somewhat stymied in their efforts at the seemingly more banal task of using stem cells and grafts to help heal major fractures, bones removed in surgery and other hard-to-fix injuries inside the body.

That’s where materials science comes in.

University of Rochester biomedical engineer Danielle Benoit encapsulated bone progenitor cells in a hydrogel wrapper and placed it on the bone she aimed to heal. Benoit hoped the wrapper would result in fewer stem cells being washed away and more sticking around to do the work of healing the bone…”

via
​http://singularityhub.com/2014/06/23/delivering-capsules-of-stem-cells-helps-repair-injured-bones/

SHE WASN’T DEAD ENOUGH FOR STEM CELLS IN THE US

In ALL ARTICLES, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on June 19, 2014 at 9:22 am

Finding no promising treatment programs in the United States, and nothing that would be covered by her health insurance, Cristy traveled to Istanbul, Turkey, in 2011 for a life-saving stem-cell transplant

WHY!

CRISTY SCT
University of Hawaii Professor, Stem Cell Transplant Surgery Survivor and author of “5 Steps To Being Your Own Patient Advocate” is taking her “5 Steps Movement” on the road in July….

Cristy Kessler, Ed.D., NBCT

With over 19 years of teaching experience, Dr. Cristy Kessler has been motivating audiences of all ages with her message of determination, survival, faith, and hope. Cristy has a natural ability for speaking to large groups of people of all ages and a style of speaking that helps them feel like they’re sitting in her living room.

Cristy Kessler has been a role model for countless students from 5th grade through university whose lives she has touched as a social studies teacher, coach, and associate professor in education at the University of Hawaii. This, in spite of a lifetime of pain and a constant battle with health issues throughout her life.

A three-sport standout in high school, Cristy coached both soccer and basketball, including a five-year stint as coach for TourneySport USA in Hawaii. She earned her doctorate in educational leadership and innovation in 2003, and as part of her commitment to being the best teacher and role model she could be, she achieved certification through the National Board for Professional Teaching Standards (NBPTS), even though this certification is generally recognized as a program for K-12 teachers. Rarely has a university professor sought (or achieved) this recognition, but Cristy did exactly that in 2005, even as she was recovering from cancer surgery. In her role as an associate professor at the university, she has guided scores of teachers through successful achievement of NBPTS certification.

Plagued by constant pain and fatigue, Cristy was finally diagnosed in 2006 with a constellation of auto-immune diseases: scleroderma, ankylosing spondylitis, and vasculitis, any one of which is ultimately fatal. Following years of treatment for the symptoms of these disorders, it became clear that the only way to save her life was to somehow tackle the diseases themselves, not just the symptoms. Finding no promising treatment programs in the United States, and nothing that would be covered by her health insurance, Cristy traveled to Istanbul, Turkey, in 2011 for a life-saving stem-cell transplant at Anadolu Hospital, an affiliate of Johns Hopkins University. Extensive fund-raising efforts by friends and family helped make this incredible journey a reality.

The transplant succeeded such that Cristy has a brand-new immune system and has resumed her work with university students and teachers. She continues to look for opportunities to inspire and encourage others through the story of her determination to live, even in the face of chronic pain and imminent death.

Dr. Kessler recently released a new book, “5 Steps To Being Your Own Patient Advocate” and is touring in July in support of the book.

Check out the current tour schedule at:
http://www.5stepstobeingyourownpatientadvocate.com

“My Health. My Body. My Voice….Learning To Live Tour” campaign:
https://www.indiegogo.com/projects/my-health-my-body-my-voice-learning-to-live-tour/x/3387656

You can read Cristy’s compelling story at:
http://www.cristykessler.com

Youtube Channel:
https://www.youtube.com/channel/UCoL–mQB2KXhcVkJXxMZwFg

YOUR BRAIN, THE EMPTY CUP

In SCIENCE & STEM CELLS, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on June 4, 2014 at 8:40 am

empty-cup  819px-Complete_neuron_cell_diagram_en.svg

15 years ago, modern science was confronted with the premise that HEART type cells could regenerate, overturning hundreds of years of empirical knowledge including over 400 years of clinical trial results (The first clinical trial of a novel therapy was conducted unintentionally by the Renaissance surgeon Ambroise Parè in 1537).  Ask your doctor if heart cells can regenerate.  There is still ENORMOUS resistance.

10 years ago, modern science was confronted with the premise that BRAIN type cells could regenerate, overturning hundreds of years of empirical knowledge including over 400 years of clinical trial results.  Ask your doctor if brain cells can regenerate.  There is still ENORMOUS resistance.

3 days ago Duke researchers published a study in the peer reviewed journal Nature about how they “found a new type of neuron in the adult brain that is capable of telling stem cells to make more new neurons.”

While this is incredible news, science is still moving too slowly for those suffering from chronic and terminal diseases, dementia, TBI and other neurological disorders.  Is it time to revamp the system?  Is it time to approach healing and science with the premise that the human body has regenerative capabilities and we should tap into those systems to heal disorders instead of treating symptoms far removed from the original disorders?  What other premises are in place which are blocking medical advancements?

A story from Zen Buddhism:
Nan-in served tea. He poured his visitor’s cup full, and then kept on pouring.  The professor watched the overflow until he no longer could restrain himself. “It is overfull. No more will go in!”  “Like this cup,” Nan-in said, “you are full of your own opinions and speculations. How can I show you Zen unless you first empty your cup?”

Regenerative medicine is a new frontier.  Already around for decades, most have yet to recognize it as the huge paradigm shift which necessitates our emptier our cups and approaching medicine from a completely new perspective.  A new perspective which includes an empty cup.

Is your thinking, holding you back?

via
http://www.sciencedaily.com/releases/2014/06/140602102006.htm
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.3734.html

HOPKINS CANCER UPDATE?

In STEM CELLS IN THE NEWS on May 28, 2014 at 11:42 am

​Let’s be careful out there guys.  While every word in the below article MAY be true, there is no association whatsoever between this list and John Hopkins.  The first clue is that there are no references, no footnotes, no backlinks.  Then you go to Hopkins and see they have called it a hoax – http://m.hopkinsmedicine.org/kimmel_cancer_center/news_events/featured/cancer_update_email_it_is_a_hoax.html and finally, Snopes shoots it down -

http://www.snopes.com/medical/disease/cancerupdate.asp

What’s very frustrating to me is that the dissemination of unreferenced data damages the hard work of “non-traditional” healers and healing techniques and makes anything with “alternative”, “holistic”, “natural”, etc seem to be a scam via guilt by association.  Is there truth in the above? Maybe, but finding it out just got set back significantly as the baby gets thrown out with the bathwater.

Science is a tool.  It’s neither good nor evil.  And there are many, many studies showing huge benefits from  “alternative”, “holistic”, “natural”, therapies.  Science is also slow and there typically needs to be a huge $ sign and a mass producible and patentable pill at the end of the road (7-10 yrs and $250 million) for a study/trial to happen.  These are some of the reasons stem cell treatments are taking so long to get into mainstream Western medicine.   http://repairstemcell.wordpress.com/why-no-stem-cells-in-the-us Part1/

Techniques described as “alternative”, “holistic” and “natural” are essentially working with a huge handicap on many levels.  I am all for ‘changing the system’ as it is fundamentally broken. http://repairstemcell.wordpress.com/why-are-there-still-no-stem-cells-in-the-us Part2/  but this is not the way.  Ultimately, sharing this info without references damages those looking for real healing options.

-David

 

Image
Big Hospital Finally telling the truth about Cancer, Johns Hopkins

LATEST CANCER INFORMATION
from Johns Hopkins

AFTER YEARS OF TELLING PEOPLE CHEMOTHERAPY IS THE ONLY WAY TO TRY AND ELIMINATE CANCER, JOHNS HOPKINS IS FINALLY STARTING TO TELL YOU THERE IS AN ALTERNATIVE WAY …

1. Every person has cancer cells in the body. These cancer cells do not show up in the standard tests until they have multiplied to a few billion. When doctors tell cancer patients that there are no more cancer cells in their bodies after treatment, it just means the tests are unable to detect the cancer cells because they have not reached the detectable size.

2. Cancer cells occur between 6 to more than 10 times in a person’s lifetime.

3. When the person’s immune system is strong the cancer cells will be destroyed and prevented from multiplying and forming tumors.

4. When a person has cancer it indicates the person has multiple nutritional deficiencies. These could be due to genetic, environmental, food and lifestyle factors.

5. To overcome the multiple nutritional deficiencies, changing diet and including supplements will strengthen the immune system.

6. Chemotherapy involves poisoning the rapidly-growing cancer cells and also destroys rapidly-growing healthy cells in the bone marrow, gastro-intestinal tract etc, and can cause organ damage, like liver, kidneys, heart, lungs etc.

7. Radiation while destroying cancer cells also burns, scars and damages healthy cells, tissues and organs.

8. Initial treatment with chemotherapy and radiation will often reduce tumor size. However prolonged use of chemotherapy and radiation do not result in more tumor destruction.

9. When the body has too much toxic burden from chemotherapy and radiation the immune system is either compromised or destroyed, hence the person can succumb to various kinds of infections and complications.

10. Chemotherapy and radiation can cause cancer cells to mutate and become resistant and difficult to destroy. Surgery can also cause cancer cells to spread to other sites.

11. An effective way to battle cancer is to STARVE the cancer cells by not feeding it with foods it needs to multiple.

What cancer cells feed on:

a. Sugar is a cancer-feeder. By cutting off sugar it cuts off one important food supply to the cancer cells. Note:Sugar substitutes like NutraSweet, Equal, Spoonful, etc are made with Aspartame and it is harmful. A better natural substitute would be Manuka honey or molasses but only in very small amounts. Table salt has a chemical added to make it white in colour. Better alternative is Bragg’s aminos or sea salt.

b. Milk causes the body to produce mucus, especially in the gastro-intestinal tract. Cancer feeds on mucus. By cutting off milk and substituting with unsweetened soy milk, cancer cells will starved.

c. Cancer cells thrive in an acid environment. A meat-based diet is acidic and it is best to eat fish, and a little chicken rather than beef or pork. Meat also contains livestock antibiotics, growth hormones and parasites, which are all harmful, especially to people with cancer.

d. A diet made of 80% fresh vegetables and juice, whole grains, seeds, nuts and a little fruits help put the body into an alkaline environment. About 20% can be from cooked food including beans. Fresh vegetable juices provide live enzymes that are easily absorbed and reach down to cellular levels within 15 minutes t o nourish and enhance growth of healthy cells.

To obtain live enzymes for building healthy cells try and drink fresh vegetable juice (most vegetables including bean sprouts) and eat some raw vegetables 2 or 3 times a day. Enzymes are destroyed at temperatures of 104 degrees F (40 degrees C).

e. Avoid coffee, tea, and chocolate, which have high caffeine. Green tea is a better alternative and has cancer-fighting properties. Water–best to drink purified water, or filtered, to avoid known toxins and heavy metals in tap water. Distilled water is acidic, avoid it.

12. Meat protein is difficult to digest and requires a lot of digestive enzymes. Undigested meat remaining in the intestines will become putrified and leads to more toxic buildup.

13. Cancer cell walls have a tough protein covering. By refraining from or eating less meat it frees more enzymes to attack the protein walls of cancer cells and allows the body’s killer cells to destroy the cancer cells.

14. Some supplements build up the immune system (IP6, Flor-ssence, Essiac, anti-oxidants, vitamins, minerals, EFAs etc.) to enable the body’s own killer cells to destroy cancer cells. Other supplements like vitamin E are known to cause apoptosis, or programmed cell death, the body’s normal method of disposing of damaged, unwanted, or unneeded cells.

15. Cancer is a disease of the mind, body, and spirit. A proactive and positive spirit will help the cancer warrior be a survivor.

Anger, unforgiving and bitterness put the body into a stressful and acidic environment. Learn to have a loving and forgiving spirit. Learn to relax and enjoy life.

16. Cancer cells cannot thrive in an oxygenated environment. Exercising daily, and deep breathing help to get more oxygen down to the cellular level. Oxygen therapy is another means employed to destroy cancer cells.

LYME DISEASE VIDEO

In STEM CELLS IN THE NEWS on May 23, 2014 at 8:16 am

LYME DISEASE
As you are tracking through the woods, are you concerned about lyme disease?  LYME DISEASE IS THE #1 WORLD EPIDEMIC. And you can and probably will get it in your own backyard. Time to learn. http://vimeo.com/95647143

TIcks sit at the top of blades of grass for weeks till they find a victim. You, a mouse, a deer, your dog.
The password to view movie is capital LD

FDA GETTING INTO STEM CELLS?

In STEM CELLS IN THE NEWS on April 23, 2014 at 4:23 pm
http://repairstemcell.files.wordpress.com/2014/04/e6851-mk7.jpg?w=582&h=331
 
IS THE FDA FINALLY, PUBLICLY, GETTING INTO STEM CELLS?
Better late than never…14 years after serious adult stem cell research began in other parts of the world, the FDA finally woke up and they are beginning, BEGINNING to research adult stem cells. They even made a positive statement about their regenerative promise. We’ll call this one a victory in that the outcry for adult stem cells has been so loud, the FDA finally relented and have begun research. Better late than never. Thanks for coming to the party FDA…

But…14 years late to the party. Reminds me of the last scene in Schindler’s list. How many lives could have been saved? How much suffering could have been eased. Well, let’s do the math.

“…in 2005 there were 2,448,000 deaths in the u.s.
4 of the top 6 killers were:

Heart disease (652,000 deaths)
Cancer (559,000 deaths)
Stroke (143,000 deaths)
Diabetes (75,000 deaths)

There were a total of 1,429,000 deaths in 2005 from these 4 diseases and there are renowned stem cell treatment centers around the world that have been successfully treating patients with these disease for years. Around the world, people with these disease are actively receiving asc treatments and benefiting from them.

How many of those 1,429,000 deaths in the USA Could have been averted with asc treatment? How many of those 1,429,000 lives in the u.s. Could have been extended with asc treatment until other treatments were available? We’ll never know. Maybe we could have saved 30% of those people with asc or 428,700 people per year. Over 10 years that might amount to 4,287,000 people saved.

Saving 10% = 142,900 per year or 1,429,000 people saved in 10 years.
Even saving just 2% = 28,580 people per year amounts to 285,800 over 10 years.” [With a potential of 15,000,000 saved over 10 years.]
via http://repairstemcell.wordpress.com/stem-cells-101/

So when the FDA starts tooting their horn about showing up to the party, doing great research, working on unprecedented projects, the promise of adult stem cells and the ultimate success they will achieve…remind them they are doing so on the tail coats of the innumerable scientists, doctors and patients who have blazed the path before them…and please remind them to apologize to the millions who have died waiting for stem cell treatments in the USA. http://repairstemcell.wordpress.com/why-no-stem-cells-in…/

http://www.fda.gov/ForConsu…/ConsumerUpdates/ucm393030.htm

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