DAVID GRANOVSKY

Posts Tagged ‘scienc’

Engineered stem cells seek out and kill HIV infection in living organisms

In VICTORIES & SUCCESS STORIES on April 15, 2012 at 1:52 pm

“…stem cells can be genetically engineered into HIV-fighting cells…”

is there anything they can’t do???

http://cbssanfran.files.wordpress.com/2010/10/hiv_aids_generic.jpg?w=300

Engineered stem cells seek out and kill HIV infection in living organisms

Washington, Sun, 15 Apr 2012 ANI

Washington, Apr 15 (ANI): In a new study, scientists have expanded on previous research that had provided proof-of-principal that human stem cells can be genetically engineered into HIV-fighting cells.

This time, they have demonstrated that these cells can actually attack HIV-infected cells in a living organism.

The study by UCLA researchers demonstrate for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues in an animal model.

“We believe that this study lays the groundwork for the potential use of this type of an approach in combating HIV infection in infected individuals, in hopes of eradicating the virus from the body,” Scott G. Kitchen, lead investigator of the study, said.

In the previous research, the scientists took CD8 cytotoxic T lymphocytes – the “killer” T cells that help fight infection – from an HIV-infected individual and identified the molecule known as the T cell receptor, which guides the T cell in recognizing and killing HIV-infected cells.

However, these T cells, while able to destroy HIV-infected cells, do not exist in great enough quantities to clear the virus from the body. So the researchers cloned the receptor and used this to genetically engineer human blood stem cells.

http://www.differencebetween.co.in/wp-content/uploads/2011/05/Mouse.jpg

They then placed the engineered stem cells into human thymus tissue that had been implanted in mice, allowing them to study the reaction in a living organism.

The engineered stem cells developed into a large population of mature, multi-functional HIV-specific CD8 cells that could specifically target cells containing HIV proteins.

The researchers also discovered that HIV-specific T cell receptors have to be matched to an individual in much the same way an organ is matched to a transplant patient.

In this current study, the researchers similarly engineered human blood stem cells and found that they can form mature T cells that can attack HIV in tissues where the virus resides and replicates. They did so by using a surrogate model, the humanized mouse, in which HIV infection closely resembles the disease and its progression in humans.

In a series of tests on the mice’s peripheral blood, plasma and organs conducted two weeks and six weeks after introducing the engineered cells, the researchers found that the number of CD4 “helper” T cells – which become depleted as a result of HIV infection – increased, while levels of HIV in the blood decreased.

CD4 cells are white blood cells that are an important component of the immune system, helping to fight off infections. These results indicated that the engineered cells were capable of developing and migrating to the organs to fight infection there.

The researchers did note a potential weakness with the study: Human immune cells reconstituted at a lower level in the humanized mice than they would in humans, and as a result, the mice’s immune systems were mostly, though not completely, reconstructed.

Due to this, HIV may be slower to mutate in the mice than in human hosts. So the use of multiple, engineered T cell receptors may be one way to adjust for the higher potential for HIV mutation in humans.

“We believe that this is the first step in developing a more aggressive approach in correcting the defects in the human T cell responses that allow HIV to persist in infected people,” Kitchen added.

The study has been published in the journal PLoS Pathogens. (ANI)

Engineered stem cells seek out and kill HIV infection in living organisms.

TRAUMATIC BRAIN INJURY and STROKE

In DISEASE INFO on March 26, 2012 at 1:17 am

TO SEE IF YOU ARE A CANDIDATE FOR STEM CELL TREATMENT, PLEASE FILL OUT THE FOLLOWING FORM:  STEM CELL PATIENT QUESTIONNAIRE

I was told this was a con…here is my response:

My Stem Cells vs. Stroke page:
http://repairstemcell.wordpress.com/stroke-stem-cells/

Additional articles sorted by date (YEAR/MONTH/DAY):
http://repairstemcell.wordpress.com/2012/03/06/stem-cells-safe-for-young-traumatic-brain-injury/
http://repairstemcell.wordpress.com/2012/01/22/cellnews-scientists-learn-how-stem-cell-implants-help-heal-traumatic-brain-injury/

http://www.sciencedaily.com/releases/2011/08/110831160216.htm
http://repairstemcell.wordpress.com/2011/10/17/regenerating-the-central-nervous-system/

http://repairstemcell.wordpress.com/2010/09/20/stem-cell-treatment-for-stroke-and-traumatic-brain-injury-wholewellness-net/
http://repairstemcell.wordpress.com/2010/09/21/autologous-neural-stem-cells-benefit-parkinson%e2%80%99s-patients-adultstemcell-com/
http://repairstemcell.wordpress.com/2010/09/20/stem-cell-treatment-for-stroke-and-traumatic-brain-injury-wholewellness-net/
http://repairstemcell.wordpress.com/2010/08/28/cord-blood-wakes-up-drowning-victim%e2%80%99s-brain/
http://www.scientificamerican.com/article.cfm?id=can-stem-cells-block-stroke-damage
http://repairstemcell.wordpress.com/2010/07/12/stem-cell-gel-helps-repair-traumatic-brain-injuries-smartplanet/
http://www.scientificamerican.com/article.cfm?id=can-stem-cells-block-stroke-damage
http://repairstemcell.wordpress.com/2010/04/28/stem-cells-from-menstrual-blood-may-benefit-stroke-patients/

http://repairstemcell.wordpress.com/2009/04/20/stem-cell-research-shows-adult-stem-cells-help-stroke-victims-adult-stem-cell-research/
http://www.texmedctr.tmc.edu/root/en/TMCServices/News/2009/07-01/Stem+Cells+Tested+for+Treatment+of+Stroke.htm

A con? Ok my skeptical friends, I understand. You’ve been researching stroke treatments for so long and been so disheartened you don’t believe your condition can ever improve. You’ve read all the outdated literature saying the central nervous system can not regrow (except for the most recent studies which prove it can be.) You’ve skimmed my articles and realize they are uncorroborated by “hard science.”

Fair enough. Ignore the 14 articles above which show the positive benefits of adult stem cells on stroke. You’re right, they are unsubstantiated. They are not peer reviewed medical journal articles. I appreciate your skepticism but know this:

*there are over 2,600 peer reviewed medical journal clinical trials that utilized adult stem cells with a record of safety and efficacy,
*there are many trials that cover the use of adult stem cells for stroke, ataxia, TBI, etc
*there are 60 trials that have the key words “adult stem cell” and “stroke.”
*there are 14 “Completed” trials that have the key words “adult stem cell” and “stroke.”

Research it yourself if you like. http://clinicaltrials.gov/ct2/results?term=adult+stem+cell+stroke&pg=1&show_flds=Y

Here are only the 14 “completed” trials:

Completed Efficacy Study of CD34 Stem Cell in Chronic Stroke Patients

Conditions: Stroke;   Middle Cerebral Artery Infarction
Interventions: Procedure: Intercerebral implantation of Autulogous Stem Cells;   Drug: convention therapy
Completed Intravenous Autologous Bone Marrow-derived Stem Cells Therapy for Patients With Acute Ischemic Stroke

Condition: Acute Stroke
Intervention: Biological: Autologous bone marrow stem cell
Completed Autologous Bone Marrow Stem Cells in Middle Cerebral Artery Acute Stroke Treatment.

Conditions: Stroke, Acute;   Infarction, Middle Cerebral Artery
Intervention: Procedure: Infusion on autologous CD34+ stem cells into middle cerebral artery
Completed Study of Autologous Stem Cell Transplantation for Patients With Ischemic Stroke

Condition: Infarction, Middle Cerebral Artery
Intervention: Other: Autologous cell transplantation
21 Completed Granulocyte-colony Stimulating Factor for Stem Cells Therapy for Acute Ischemic Stroke

Condition: Ischemic Stroke
Intervention: Drug: Filgrastim
31 Completed Sickle Cell Disease and Endothelial Progenitor Cells (EPCs)

Condition: Sickle Cell Anemia
Intervention: Procedure: Angiography
34 Completed Investigating Endothelial Precursor Cells (EPCs)

Condition: Central Nervous System
Intervention:
38 Completed Immunological Mechanisms of Hematopoietic Stem Cell Transplantation in Multiple Sclerosis

Condition: Multiple Sclerosis
Intervention: Procedure: Stem Cell Transplanataion
40 Completed Gene Therapy for Gaucher’s and Fabry Disease Using Viruses and Blood-Forming Cells

Condition: Gaucher’s Disease
Intervention: Genetic: human glucocerebrosidase cDNA
51 Completed Single-Dose Pharmacokinetics (PK) Study of Novel Neurogenic Compound NSI-189

Condition: Depression
Intervention: Drug: NSI-189 Phosphate
52 Completed Beta-hCG + Erythropoietin in Acute Stroke

Condition: Acute Stroke
Intervention: Drug: Beta-hCG + Erythropoietin
54 Completed Effects of Hyperbaric Oxygen Therapy in Autistic Children: A Pilot Study

Conditions: Autism;   Oxidative Stress;   Inflammation
Intervention: Drug: Hyperbaric Oxygen Therapy
59 Completed Effects of Enzyme Replacement in Gaucher’s Disease

Condition: Gaucher’s Disease
Intervention:
60 Completed Incidence of Ocular Antibodies in Patients With Sturge – Weber Syndrome (SWS)

Condition: Sturge – Weber Syndrome (SWS)
Intervention:

 

 

If you still feel this is a con, tell me what you would need to see to prove otherwise. Respectfully, David

ABORTION, EMBRYONIC STEM CELLS, CRICHTON and PHARMA

In ALL ARTICLES on March 19, 2012 at 2:03 am
ABORTION, EMBRYONIC STEM CELLS, CRICHTON and PHARMA:
insidious analysis…i been around the block once or twice and traveled and listened enough to know that things are not always what they seem and the reasons for doing so are rarely what they appear.

women’s rights are getting squeezed and rung out of them like yesterday’s dirty sponge water and while this is a travesty in and of itself I can’t help but believe that this is the beginning of many more injustices and changes which will make our heads spin. is this an effort to establish that: your body is not your own? we no longer have the right to choose what we put in our body (from vaginal probes to GMOs so “our bodies/your property” seems closer than i care to admit…

For an absolutely chilling account of “Our Bodies, Your Property” read this:

Basically, if a woman is state or corporate property, then so is her fetal matter; so doctors can remove the biological materials and use it with legal backing? OR, if a woman is genetically resistant to a specific disease, maybe they can just claim her child and use it for testing?

more and more i see actions performed under the umbrella excuse “the good of the many outweighs the needs of the few” How long before the health of the many is worth the death of the one? perhaps this an embryonic stem cell angle? one last gasp of pharma to fool the public into carrying the embryonic stem cell torch despite the FACT that embryonic stem cell treatments don’t work and do cause tumors?

this isn’t out of the realm of reality, if you disbelieve, go read Mike Chrichton’s 2006 book NEXT – “…and that the physician’s university had sold the rights in Frank’s cells to BioGen, a biotechnology startup company. As the book opens Frank is suing the university for unauthorized misuse of his cells, but the trial judge rules that the cells were “waste” that the university could dispose of as it wished. Frank’s lawyers advise that, even if he wins an appeal, the university as a tax-funded organization can still claim the rights to the cells under the doctrine of eminent domain.”

The pharma company then goes after his kids since the genetic material is the same and if they own the father, the own the son (and the sins of the father shall be visited on the sons…the genetic commerical potential tool) M.C. said about this book: “This novel is fiction, except for the parts that aren’t.”

We’ll see…this goes in the category of “i hope i’m wrong but this twisting in my gut is telling me otherwise”

Egg-making stem cells found in adult ovaries : Nature

In SCIENCE & STEM CELLS on March 4, 2012 at 9:12 am

http://remodelista.com/img/sub/uimg//04-2011/merchant-4-cara-egg-cup.jpg

Egg-making stem cells found in adult ovaries

27 February 2012

Discovery could pave the way for new fertility treatments and a longer reproductive life.

It’s time to rewrite the textbooks. For 60 years, everyone from high-school biology teachers to top fertility specialists has been operating under the assumption that women are born with all the eggs they will ever produce, with no way to replenish that supply. But the discovery of human egg-producing stem cells, harvested from the ovaries of six women aged 22 to 33, puts that dogma in doubt.

The work, published online in Nature Medicine1 by Jonathan Tilly and colleagues at Massachusetts General Hospital in Boston, parallels the findings of a Shanghai-based group2 that isolated similar stem cells from mice in 2009. However, both this and Tilly’s earlier work in mice3 remained controversial, with many experts sceptical that such stem cells existed.

“This is unequivocal proof that not only was the mouse biology correct, but what we proposed eight years ago was also correct — that there was a human population of stem cells in young adult tissue,” says Tilly…

Read more: Egg-making stem cells found in adult ovaries : Nature News & Comment.

RELATED ARTICLES
27 February 2012 – by Antony Blackburn-Starza
Scientists in the USA have shown it may be possible to isolate egg-producing stem cells from women’s ovaries….[Read More]
20 April 2009 – by Dr Charlotte Maden
New work in stem cell research has challenged the long-standing belief that women are born with all the eggs they will ever need. The results were published in the journal Nature Stem Cell, although the study was received with caution. The scientists at Shanghai Jiao Tong University…[Read More]
21 May 2007 – by Stuart Scott
Hopes aroused by a controversial study suggesting that women may be able to produce new egg cells have been seemingly dashed. The 2005 paper, published in the journal Cell by researchers at Massachusetts General Hospital, fleetingly gave hope to infertile women when it suggested that egg production…[Read More]
16 June 2006 – by Dr Jess Buxton
A new US study has cast serious doubt on controversial research that suggested bone marrow stem cells can produce new eggs in adult mice. Last year, a team based at Massachusetts General Hospital reported in the journal Cell that the eggs of mice rendered sterile could…[Read More]
03 October 2005 – by BioNews
A US woman who became infertile after cancer treatment has stunned doctors by becoming pregnant naturally, following a transplant of ovarian tissue into her abdomen. Ann Dauer, from Canton, Ohio has now given birth to a healthy baby girl, named Sienna. Mrs Dauer had one of her ovaries removed and…[Read More]

Blueprint of Stem Cell Wiring Gives Scientists Control

In SCIENCE & STEM CELLS on March 3, 2012 at 12:47 am

http://itdevworld.files.wordpress.com/2010/06/blueprint.jpg?w=391&h=294

Blueprint of Stem Cell Wiring Gives Scientists Control

March 2, 2012

Despite the promise associated with the therapeutic use of human stem cells, a complete understanding of the mechanisms that control the fundamental question of whether a stem cell becomes a specific cell type within the body or remains a stem cell has-until now-eluded scientists.

A Univ. of Georgia study published in today’s edition of the journal Cell Stem Cell, however, creates the first ever blueprint of how stem cells are wired to respond to the external signaling molecules to which they are constantly exposed. The finding, which reconciles years of conflicting results from labs across the world, gives scientists the ability to precisely control the development, or differentiation, of stem cells into specific cell types.

Laboratory Equipment – Blueprint of Stem Cell Wiring Gives Scientists Control.

EMBRYONICS’ BLEAK FUTURE AND BOTCHED PAST

In ALL ARTICLES on November 15, 2011 at 6:42 pm

Request more treatment info.

EMBRYONICS’ BLEAK FUTURE AND BOTCHED PAST

BLEAK FUTURE

I just received a comment from MB and despite Geron and the rest of the world abandoning embryonic stem cells for adult, he is still optimistic about the future of embryonic stem cells (with a little plug snuck in for a company he probably owns stock in).

My original comment:

embryonic research has been 100% fruitless (in regard to generating
treatments) for well-funded and government supported scientists around the world for the last 13 years.  Embryonic stem cells are the only significant obstacles to embryonic stem cell treatments.  Adult stem cells on the other hand have successfully treated 10s of thousands over the past decade.

MB’s response:

hESCs (human embryonic stem cells) have only been around for 13 years compared to adult stem cells 30+ years…. give it some time… human embryonic stem cells (especially ACT’s embryo SAFE blastomere-derived) will be THE GOLD standard :)  watch and SEEE the difference…soon..

My response:

MB – Not even close.   Embryonic stem cells have been around for way longer than since James Thompson and friends derived the first human embryonic stem cell line at the University of Wisconsin-Madison in 1998.

To clarify:

“Research in the human stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s.”

1963: Becker AJ, McCulloch EA, Till JE (1963). “Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells”. Nature 197: 452-4. PMID 13970094.

1963: Siminovitch L, McCulloch EA, Till JE (1963). “The distribution of colony-forming cells among spleen colonies”. Journal of Cellular and Comparative Physiology 62: 327-36. PMID 14086156.

1978: Stem cells were discovered in human cord blood

1981: First in vitro stem cell line developed from mice

1981 – Mouse embryonic stem cells are derived from the inner cell mass

That’s 30 years ago!

Evans, M.J. & Kaufman, M. Establishment in culture of pluripotential stem cells from mouse embryos. Nature 292, 151–156 (1981).

1981 – Martin, G.R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci USA 78, 7634–7638 (1981).

1984 – Andrews, P.W. et al. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Lab. Invest. 50, 147–162 (1984).

Blastomeres isolated from the ICM of mammalian embryos and grown in culture are known as embryonic stem (ES) cells. These pluripotent cells, when grown in a carefully coordinated media, can give rise to all three germ layers (ectoderm, endoderm, and mesoderm) of the adult body.

1986: Robertson, Elizabeth , et al. Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector. Nature 323, 445 – 448 (02 October 1986)

1988: Embryonic stem cell lines created from a hamster

1995: First embryonic stem cell line derived from a primate

1995: Thomson, J.A. et al. Isolation of a primate embryonic stem cell line. Proc. Natl. Acad. Sci. USA 92, 7844–7844 (1995).

And then we get to what MB considers the “discovery of embryonic stem cells”:

1998 – James Thomson and coworkers derive the first human embryonic stem cell line at the University of Wisconsin-Madison.

Not to worry, though MB.  Adult stem cells HAVE been used in bone marrow transplants for over 40 years so they still have the upper hand in “time we’ve worked with them.”  Then again, it was only in 1998 that adult stem cells were considered for treating other illnesses.

Just out of curiosity, besides

“embryonic stem cells have proven 100% fruitless (in regard to generating treatments) for well-funded and government supported scientists around the world for the last 13 years,”

how do you plan on addressing these other embryonic stem cell issues to name a few?

  1. they create cysts and tumors that can develop into cancer at the site of the injection and injury
  2. rejection issues require immunosuppressive drugs for the ill patient
  3. embryonic stem cells (and induced pluripotent stem cells) carry the genetic anomalies of the donor
  4. they have to date treated zero diseases successfully
  5. scientists probably need to cure cancer first to use them
MIRROR THE RESULTS

MIRROR THE RESULTS

But if MB can mirror the results of  the success rate of adult stem cell treatments (~65% of patients have significant improvement in their incurable, chronic or terminal illnesses) and do so without the side effects alluded to above (adult stem cells have virtually zero side effects except for sometimes additionally fixing more than the intended organ/illness) then I would love to hear about it!

INTESTINAL STEM CELLS RESPOND TO FOOD BY SUPERSIZING THE GUT

In STEM CELLS IN THE NEWS on October 27, 2011 at 6:24 pm

Request more treatment info.

INTESTINAL STEM CELLS RESPOND TO FOOD BY SUPERSIZING THE GUT

SO now we know that stem cells change your body all the time to deal with changes in your environment and what you eat.  Is it getting clearer? – David

Intestinal stem cells respond to food by supersizing the gut

BERKELEY —

A new study from University of California, Berkeley, researchers demonstrates that adult stem cells can reshape our organs in response to changes in the body and the environment, a finding that could have implications for diabetes and obesity…

Intestinal stem cells respond to food by supersizing the gut.

DIABETES CLINICAL TRIALS

  • FIRST USE OF CORD BLOOD TO ALTER COURSE OF TYPE 1 DIABETES, June 25, 2007 – (I’ll bet nobody heard of this one!)transfusion of stored, autologous (i.e. the person’s own), umbilical cord blood into a group of children newly diagnosed with type 1 diabetes appears to have reduced their disease severity, possibly re-setting the immune system and slowing the destruction of their insulin-producing cells, according to a report presented today at the American Diabetes Association’s 67th Annual Scientific Sessions. –http://parentsguidecordblood.org/content/media/m_pdf/ADA_T1D_PR-06-25-07.pdf(The ADA in 2007 knew stem cells can treat Diabetes type 1 in children!)
  • Diabetes type 1 stem cell clinical trial – Enrollment 11/2003-4/2008, follow-up until December 2008 – http://repairstemcell.wordpress.com/2009/09/14/type-1-diabetes-stem-cells-clinical-trial/
  • Why no diabetes clinical trial s in the US when mice were cured of diabetes type 1 in the 1990’s? -  Weissman, a professor of pathology and developmental biology at Stanford University, states: “Stem cells are rare, self-renewing, and can regenerate body tissues.” He repeatedly expressed frustration that while many of his discoveries seemed to hold remarkable potential for life-saving treatments, commercial or regulatory hurdles have prevented his scientific research from benefiting human beings. One example is, his mid-’90s research on type I diabetes, in which he demonstrated the ability to fully cure type I diabetes in mice using stem cells. Even though the experiments avoided political controversy by using adult/repair stem cells, which do not come from embryos, Weissman ran into a road block when pharmaceutical companies refused to sponsor clinical trials. The therapy went nowhere. “The pharmaceutical companies had put profit over principle, preferring to keep diabetes sufferers dependent on costly insulin than to cure them once and for all.” – http://repairstemcell.wordpress.com/2009/09/13/research-from-90s-cures-type-1-diabetes/

If you or a loved one is interested in receiving FREE information on currently available stem cell treatments for DIABETES or PERIPHERAL ARTERY DISEASE, please contact me at dsgrano@gmail.com or for other options, go to: CONTACT ME

DIABETES and STEM CELL TREATMENTS AVAILABLE

In ALL ARTICLES on October 24, 2011 at 9:15 am

Anyone interested in treatment info with one of the best stem cell diabetes doctors in the world can contact me or fill out this form: 
TREATMENT INFORMATION REQUEST – PATIENT QUESTIONNAIRE

——————————-

Can stem cells cure Diabetes – type 1?

In VICTORIES & SUCCESS STORIES on August 31, 2009 at 12:00 pm

Can stem cells cure Diabetes – type 1? See the results of this one year study of adult stem cell treatment of Diabetes type – 1. C-peptide levels, insulin levels, insulin dosage requirements and HA1c levels.

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Can stem cells cure Diabetes – type 2?

In VICTORIES & SUCCESS STORIES on August 31, 2009 at 12:12 pm

Can stem cells cure Diabetes – type 2? See the results of this one year study of adult stem cell treatment of Diabetes type – 2.  C-peptide levels, insulin levels, insulin dosage requirements and HA1c levels.

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DIABETES CLINICAL TRIALS

  • FIRST USE OF CORD BLOOD TO ALTER COURSE OF TYPE 1 DIABETES, June 25, 2007 – (I’ll bet nobody heard of this one!)transfusion of stored, autologous (i.e. the person’s own), umbilical cord blood into a group of children newly diagnosed with type 1 diabetes appears to have reduced their disease severity, possibly re-setting the immune system and slowing the destruction of their insulin-producing cells, according to a report presented today at the American Diabetes Association’s 67th Annual Scientific Sessions. –http://parentsguidecordblood.org/content/media/m_pdf/ADA_T1D_PR-06-25-07.pdf(The ADA in 2007 knew stem cells can treat Diabetes type 1 in children!)
  • Diabetes type 1 stem cell clinical trial – Enrollment 11/2003-4/2008, follow-up until December 2008 – http://repairstemcell.wordpress.com/2009/09/14/type-1-diabetes-stem-cells-clinical-trial/

Images from above are from these articles:

  • Why no diabetes clinical trial s in the US when mice were cured of diabetes type 1 in the 1990’s? -  Weissman, a professor of pathology and developmental biology at Stanford University, states: “Stem cells are rare, self-renewing, and can regenerate body tissues.” He repeatedly expressed frustration that while many of his discoveries seemed to hold remarkable potential for life-saving treatments, commercial or regulatory hurdles have prevented his scientific research from benefiting human beings. One example is, his mid-’90s research on type I diabetes, in which he demonstrated the ability to fully cure type I diabetes in mice using stem cells. Even though the experiments avoided political controversy by using adult/repair stem cells, which do not come from embryos, Weissman ran into a road block when pharmaceutical companies refused to sponsor clinical trials. The therapy went nowhere. “The pharmaceutical companies had put profit over principle, preferring to keep diabetes sufferers dependent on costly insulin than to cure them once and for all.” – http://repairstemcell.wordpress.com/2009/09/13/research-from-90s-cures-type-1-diabetes/

If you or a loved one is interested in receiving FREE information on currently available stem cell treatments for DIABETES, please contact me at dsgrano@gmail.com or for other options, go to: CONTACT ME

Experts grow whole tooth units using mouse stem cells

In VICTORIES & SUCCESS STORIES on July 12, 2011 at 6:57 pm

 

 

 

 

 

 

 

 

Old news, I covered this story and other similar stories as far back as August of 2009 (see below)…but they are just picking it up now so I thought I would post it.  CATCH UP!!!!  –  DSG

 

Experts grow whole tooth units using mouse stem cells – Reuters
Credit: Reuters/Dr. Takashi Tsuji/Tokyo University of Science/Handout By Tan Ee Lyn HONG KONG (Reuters) – Scientists in Japan said on Wednesday they have created teeth — complete with connective fibers and bones — by using mouse stem cells and 

Main Image

New Teeth From Stem Cells in Mice

In VICTORIES & SUCCESS STORIES on August 25, 2009 at 10:11 pm

Teeth have been grown from stem cell “seeds” and planted in the mouths of mice, scientists from Tokyo University reported in Proceedings of the National Academy of Sciences. They hope it could lead to replacing teeth in humans, or even to rebuilding whole organs.

The Japanese scientists developed a bioengineered “tooth germ” — a seed-like package containing all the cells and instructions necessary to form a tooth…


Scientists grow fully functional tooth from stem cells

In VICTORIES & SUCCESS STORIES on September 8, 2009 at 1:18 pm

Scientists grow fully functional tooth from stem cells

August 22, 4:12 PMNY Holistic Body & Spirit ExaminerTima Vlasto

Though teeth have been grown in mice before, scientists revealed in the Proceedings of the National Academy of Sciences their success at growing a “fully functional” tooth from stem cells in mice…

 

 

A denture-free world with adult stem cells

In VICTORIES & SUCCESS STORIES on September 13, 2009 at 1:35 pm

bush stole my denturesNova Southeastern University’s dental researchers at the College of Dental Medicine are growing and harvesting human dental stem cells in the laboratory.A 2009 NSU survey of dentists around the nation revealed that more than half thought that they would be using stem cell and tissue engineering therapies on their patients within the next decade.

An overwhelming 96 percent of dentists believe the ability to regenerate and replace teeth and dental tissues is the future of dentistry, according to the survey…

 

Jaw bone created from (patient’s own) stem cells

In VICTORIES & SUCCESS STORIES on April 21, 2010 at 5:13 pm

Jaw bone created from (patient’s own) stem cells – BBC NEWS | Health | – New bone created in the lab

The new bone was created from bone marrow stem cells

Scientists have created part of the jaw joint in the lab using human adult stem cells.

Two points from me:

1. Cloning, shmoning! The facts is, they have already created hearts, windpipes and jawbones from adult stem cells. No clones needed, no rejection issues, no transplants, no immunosuppressive drugs,….we can just make the bone, organ, teeth, etc that fit perfectly into your body because they are made from your body (and from your own stem cells)…

 

Body’s Own Stem Cells Can Lead to Tooth Regeneration

In VICTORIES & SUCCESS STORIES on May 24, 2010 at 7:37 pm

I met with Dr. Mao last summer and I found his presentation fascinating and informative.  Imagine taking stem cells from your own body and regrowing your won teeth. No dentures, crowns, implants, foreign materials, etc. etc.  Imagine; tooth regeneration from your own body, for your own body.  -dg

Monday, May 24, 2010

Body’s Own Stem Cells Can Lead to Tooth Regeneration

A technique pioneered in the Tissue Engineering and Regenerative Medicine Laboratory of Dr. Jeremy Mao, the Edward V. Zegarelli Professor of Dental Medicine at Columbia University Medical Center, can orchestrate stem cells to migrate to a 3-D scaffold infused with growth factor, holding the translational potential to yield an anatomically correct tooth in as soon as nine weeks once implanted…

Ebryonic stem cell research funding will go on

In STEM CELLS IN THE NEWS on May 2, 2011 at 12:15 am

1. It’s spelled eMbryonic, not ebryonic. They got the most important word in the article wrong in the title and in the first word of the title no less? Are you kidding me?
2. So what? Screw the embryos, they’re irrelevant! http://repairstemcell.wordpress.com/screw-the-embryos-they%e2%80%99re-irrelevant/ – dg

Ebryonic stem cell research funding will go on, federal court rules – 5.1.11 | MassDevice Staff

Embryonic stem cellsA federal appeals court reversed a lower court’s ruling to halt federal funding of research involving human embryonic stem cells, voting 2-1 that the policy does not violate a 1996 law.

In August, Judge Royce Lamberth of the U.S. District Court for the District of Columbia banned the funding policy, potentially derailing scores of projects looking into the causes of diseases like Parkinson’s, Alzheimer’s and cystic fibrosis. President Barack Obama had sought to deliver stem cell research funding from constraints imposed under the Bush administration, but Lamberth ruled that the policy violated the Dickey-Wicker Amendment, aimed at stopping the destruction of human embryos.

Dickey-Wicker proved to be a sticky wicket for both plaintiffs and defendants when the appeals court issued a temporary stay of the Lamberth ruling.

Obama’s policy allowed the use of stem cell lines derived from frozen embryos from fertility treatments that were no longer needed and donated according to stringent ethical guidelines. The plaintiffs in the lawsuit, James Sherley and Theresa Deisher, argued that the Obama policy violated the Dickey-Wicker rules.

The Obama administration appealed the decision to the D.C. appeals bench. In a 2-1 ruling, that court overturned Lamberth’s decision.

“We conclude the plaintiffs are unlikely to prevail because Dickey-Wicker is ambiguous and the NIH seems reasonably to have concluded that, although Dickey-Wicker bars funding for the destructive act of deriving an [embryonic stem cell] from an embryo, it does not prohibit funding a research project in which an [embryonic stem cell] will be used. We therefore vacate the preliminary injunction,” Judge Douglas Ginsberg wrote in the majority opinion, according to court documents. “All this is to say the balance of equities tilts against granting a preliminary injunction. That, combined with our conclusion the plaintiffs have not shown they are likely to succeed on the merits, leads us to hold the district court abused its discretion in awarding preliminary injunctive relief..”

In a feisty dissent, Judge Karen LeCraft Henderson took issue with her colleague’s reasoning, writing that they have “taken a straightforward case of statutory construction and produced a result that would make Rube Goldberg tip his hat,” performing “linguistic jujitsu.”

“I must therefore respectfully dissent,” Henderson wrote. “Because derivation of [human embryonic stem cells] necessarily destroys a human embryo or embryos, and because derivation constitutes at least [human embryonic stem cell] research development under the amendment, all [human embryonic stem cell] research is ‘research in which a human embryo or embryos are destroyed.’ Accordingly, the plaintiffs’ challenge to the amendment is likely to succeed because the amendment prohibits the expenditure of federal funds to engage in [human embryonic stem cell] research in all of its sequences.”

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