DAVID GRANOVSKY

Posts Tagged ‘child’

YOU MUST EMPTY YOUR MIND TO LEARN

In ALL ARTICLES, OFF THE BEATEN PATH on April 30, 2013 at 4:15 pm

keep-calm-and-empty-your-mind

I’m perplexed by an apparent dichotomy…

people who are staunch supporters of education and awareness whom are so set in their convictions they are unwilling to hear any thoughts but their own, unwilling to educate themselves on things they are wholly ignorant on, unwilling to budge or even have a calm, civil, open discussions on topics. Not argument, not debate, a friendly discussion whereby 2 people put their heads together to better understand each other and the world around them.

I invite everyone to have this type of discussion with each other and with me because I know I don’t know everything and the only way to learn is to keep your own damn mouth shut for a hot second and give your own damn opinion a rest for a second. The full glass can take no more water. Empty your mind to take on more.  that’s the only way it works.

http://www.youtube.com/watch?v=LTnSEFsInp0

be water my friend

PARENTS WHO WILL STOP AT NOTHING TO HEAL THEIR OWN

In ALL ARTICLES, OFF THE BEATEN PATH on April 24, 2013 at 11:00 am

Dedicated to the amazing women (and men) who are doing everything in their power to heal their children…

Do not confuse them for a distracted and solitary parent sitting alone in a dark corner on a laptop, sipping a spritzer and dangling a toe into stem cell treatments.

These are parents who are researching for years, they network and talk to everyone they can get their hands on, they create pages and sites and media campaigns, they compare data with each other and they do it better than a super computer, more relentlessly than a pit-bull and they do not give up and do not surrender.

They are intense and even fanatical researchers with passion, drive, motivation, education and intelligence and they are going to change the entire stem cell industry from the inside out.  You can love them or hate them but do NOT get in their way.  They are blind to bureaucracy, oblivious to obstacles and dismissive of despair.  Their engines run on the nova hot burning jet fuel of a parent’s love for their child, they wield weapons built on research and science and wear impervious suits of armor forged in hope.

They are stem cell moms and they are organized and aggressive and nothing will stand in their way.

They are…

THE STEM CELL MOMFIA

wgun4

Stem Cells Safe for Young Traumatic Brain Injury

In SCIENCE & STEM CELLS on March 6, 2012 at 4:02 am
Image showing potential uses of stem cell research with traumatic brain injuries checked.
A Phase 1 clinical trial studying the safety of using bone marrow stem cells to treat traumatic brain injuries in children is reported. The procedures look to be safe even after 6 months of being applied. The image is adapted from a public domain image

Bone Marrow Stem Cells Safe for Young Traumatic Brain Injury Patients

Saturday March 3rd 2012

A procedure involving stem cells taken from patients’ own bone marrow to treat traumatic brain injury in children is safe, according to the results of a Phase 1 clinical trial.

The trial included 10 children aged 5-14 with severe traumatic brain injuries. Within 48 hours of their injuries, the children received stem cells processed from their own bone marrow.

Six months following the procedures, the children are showing no signs of further damage caused by the use of the stem cells. Though this study only points out that the procedure is safe so far, all of the children from the study had significant improvements.

Stem cell research studies such as this one are producing more and more evidence that stem cell treatments can be safe and effective.

With very few effective treatments for brain injury patients, these studies provide great promise for the future of medicine.

The University of Texas Health Science Center at Houston press release below offers more details about this and other stem cell studies.

UTHealth study: Stem cells may provide treatment for brain injuries

Preliminary results show safety of bone marrow stem cells in traumatic brain injury

Stem cells derived from a patient’s own bone marrow were safely used in pediatric patients with traumatic brain injury (TBI), according to results of a Phase I clinical trial at The University of Texas Health Science Center at Houston (UTHealth). The results were published in this month’s issue of Neurosurgery, the journal of the Congress of Neurological Surgeons.

“Our data demonstrate that the acute harvest of bone marrow and infusion of bone marrow mononuclear cells to acutely treat severe TBI in children is safe,” said Charles S. Cox, Jr., M.D., the study’s lead author and professor of pediatric neurosurgery at the UTHealth Medical School. The clinical trial, which included 10 children aged 5 to 14 with severe TBI, was done in partnership with Children’s Memorial Hermann Hospital, where Cox is director of the pediatric trauma program.

All the children were treated within 48 hours of their injury with their own stem cells, which were collected from their bone marrow, processed and returned to them intravenously. UTHealth’s Department of Neurology is also currently testing the same bone marrow stem cell procedure in adults with acute stroke. In a separate trial, Cox is testing the safety of using a patient’s own cord blood stem cells for traumatic brain injury in children.

As a Phase I trial designed to look at feasibility and safety, the study did not assess efficacy. However, after six months of follow-up, all of the children had significant improvement and seven of the 10 children had a “good outcome,” meaning no or only mild disability.

Children who survive severe TBI are often left with serious complications and disability. Currently, there are no effective treatments to protect or promote repair of the brain in these brain-injured children.

Read more: Bone Marrow Stem Cells Safe for Young Traumatic Brain Injury Patients | Neuroscience News.

47 DEATHS FROM HPV VACCINES YOU WILL NEVER READ ABOUT

In ALL ARTICLES, DISEASE INFO on October 26, 2011 at 1:55 am

THE UNLUCKY 47…

AND WHAT REALLY SCARES ME IS THAT OVER 1/2 OF THEM ARE

“CAUSE OF DEATH = UNKNOWN!”

via http://www.judicialwatch.org/files/documents/2009/vaersdeathsALL_20090616.pdf

How nasal stem cells might prevent childhood deafness

In VICTORIES & SUCCESS STORIES on March 31, 2011 at 12:35 pm
Australia is starting to catch up.  This procedure has been done in Asia, Europe and South America…just not in the USA or Australia. – dg
How nasal stem cells might prevent childhood deafness

Australian scientists have shown for the first time in mice that nasal stem cells injected into the inner ear have the potential to reverse or restore hearing during early onset sensorineural hearing loss.

Sensorineural hearing loss occurs when hearing cells in the cochlea lose their function. Frequently inherited, and usually starting during infancy and early childhood, the condition can slow a child’s development and lead to speech and language problems.

Drs Jeremy Sullivan, Sonali Pandit and Sharon Oleskevich from Sydney’s Garvan Institute of Medical Research, found that stem cells appear to release ‘factors’, or chemical substances, that help preserve the function of cochlear hearing cells, without the stem cells becoming part of the tissue of the inner ear. Their findings are published in STEM CELLS, now online.

“We are exploring the potential of stem cells to prevent or restore hearing loss in people,” said project leader Dr Sharon Oleskevich.

“The mice we are using have a very similar form of childhood deafness to their human counterparts – except, of course that mouse years are shorter. So a mouse will tend to lose their hearing within 3 months, where a person might take 8 years.”

“We are encouraged by our initial findings, because all the mice injected with stem cells showed improved hearing in comparison with those given a sham injection. Roughly half of the mice did very well indeed, although it is important to note that hearing was not completely restored to normal hearing levels.”

Adult human nasal stem cells were used in the procedure, because they are plentiful, easy to obtain and unspecialised (so have the ability to self-renew for long periods, as well as differentiate into cells with a variety of functions).

The same group of scientists has shown in previous publications that stem cells can also be used to improve hearing in noise-induced hearing loss – a condition that affects both young and older people.

It has taken 5 years to reach the current stage of research, and scientists anticipate that it will take a further decade at least for the findings to benefit people.

How nasal stem cells might prevent childhood deafness – insciences.

Couples are opting for stem cell banking

In VICTORIES & SUCCESS STORIES on March 2, 2011 at 9:12 am

An increasing number of couples are opting for stem cell banking

discovers Zeenia F Baria

Stem Cell Expert Dr Satyen Sanghavi says that stem cells are cells found in all multi cellular organisms. They’re found throughout the body, but especially in bone marrow, in the peripheral blood (your circulating blood) and in the umbilical cord. “They are characterised by the ability to renew themselves through mitotic cell division and differentiate into a diverse range of specialised cell types. Stem cells divide themselves many times to make new stem cells. They can also transform into specific cells needed by the body to heal itself. Stem cells for transplantation can come from yourself/ your own body (an autologous transplant) or, more commonly from a donor (an allogeneic transplant). Stem cells can now be grown and transformed into specialised cells with characteristics consistent with cells of various tissues such as muscles or nerves through cell culture. Highly plastic adult stem cells from a variety of sources, including umbilical cord blood and bone marrow, are routinely used in medical therapies,” says Dr Sanghavi.

What is Stem Cell Banking?
A stem cell bank is a facility, which stores stem cells for future use. Umbilical cord blood is blood that remains in the placenta and in the attached umbilical cord after childbirth. Cord blood is obtained from the umbilical cord at the time of childbirth, after the cord has been detached from the newborn. Cord blood is collected because it contains stem cells, including hematopoietic cells, which can be used to treat hematopoietic and genetic disorders. Cord blood contains all the normal elements of blood – red blood cells, white blood cells, platelets and plasma. But it is also rich in hematopoietic (blood-forming) stem cells, similar to those found in bone marrow. This is why cord blood can be used for transplantation as an alternative to bone marrow.

Why is it recommended?
Infertility Specialist, Dr Nandita Palshetkar says that stem cell banking is a simple, safe and painless procedure and happens immediately after birth after cutting the cord. “The cord blood collected is then transferred to the laboratory and frozen in cryogenic storage tanks for long-term preservation. Nowadays, the umbilical cord is also stored. Stem cells represent an exciting area in medicine because of their potential to regenerate and repair damaged tissue. Some current therapies, such as bone marrow transplantation, already make use of stem cells and their potential for regeneration of damaged tissues. Other therapies are under investigation that involve transplanting stem cells into a damaged body part and directing them to grow and differentiate into healthy tissue,” says Dr Palshetkar.

Benefits
Storing your baby’s umbilical cord blood stem cells is an investment towards the future health of the family. “It ensures an exact match for the child and a more likely match for another blood-related family member, should the stem cells be needed for treatment. Unfortunately, if a stem cell treatment is indicated, families that have not privately banked their child’s cord blood stem cells end up searching for an appropriate source of compatible stem cells – searches, which can take months and still be unsuccessful. Cord blood stem cells from a family member are much more likely to be successfully transplanted than those from an unrelated donor,” says Dr Sanghavi.

Difference between stem cells from cord blood v/s bone marrow
Both bone marrow and cord blood stem cell transplants are designed to replace unhealthy cells with healthy ones. “Cord blood is blood that is collected from an infant’s umbilical cord after delivery, so that it may be tested, frozen and subsequently stored in a cord blood bank for future use. A bone marrow transplant, on the other hand, involves the use of bone marrow that is transplanted from a donor into the recipient in order to cultivate new stem cells. Stem cells are available in greater proportion from the umbilical cord as compared to bone marrow. Cord blood cells are have more generative capacity as compared to bone marrow cells. Cord blood cells can be used for those with lung, heart and kidney disease where bone marrow cells are to be avoided,” says Dr Palshetkar.

Conclusion
Gynaecologist Dr Sonal Kumta says that more parents should opt for stem cell banking. “Cord blood can be stored by cryopreservation for future use for your child or any other family member. The baby will have a 100 per cent match with these cells and siblings will have 25 per cent match. This once in a lifetime opportunity helps preserve a biological resource for future use. It helps protect one from incurable diseases like leukemia and thalassemia while trials are in progress for Alzheimers, cartilage regeneration, diabetes, heart diseases, liver diseases, multiple sclerosis, muscular dystrophy, spinal cord injury and even strokes.”

STEM CELL CLINICAL TRIALS for BRAIN INJURED CHILDREN?

In SCIENCE & STEM CELLS on August 16, 2010 at 2:03 pm

There are 80 clinical trials at clinicaltrials.gov that have both “stem cell” and brain and focused on or included children 0-17 yrs old:
http://clinicaltrials.gov/ct2/results?term=%22stem+cell%22+brain&recr=&rslt=&type=&cond=&intr=&outc=&lead=&spons=&id=&state1=&cntry1=&state2=&cntry2=&state3=&cntry3=&locn=&gndr=&age=0&rcv_s=&rcv_e=&lup_s=&lup_e=

brain

STEM CELLS FOR AUTISM

In SCIENCE & STEM CELLS on October 26, 2009 at 6:49 pm

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“STEM CELLS FOR AUTISM – PROGRESS TO DATE”

A parent’s caution and skepticism when evaluating whether stem cell treatment for their child’s Autism is warranted given the number of times “miracle cure for autism” has been crammed down their throats.  Placebo and expectation effects are definitely a legit concern…but (you knew there was a but, didn’t you), if you look at the science of adult or repair stem cells (these are not embryonic btw), here’s what you will find:

1.  General results:

There have been ~1300 peer reviewed, FDA approved, clinical trials with adult stem cells to date and most (almost all) have shown that adult stem cell implantation is safe and effective and provides therapeutic benefit to the patient. http://repairstemcell.wordpress.com/2009/10/10/do-stem-cell-treatments-work/

2.  Autism specific results:

As for Autism and stem cells, there haven’t been any FDA approved clinical trials completed to date, except for the hyperbaric chamber trial, which is weak and tangential at best.  The argument appears to be:

  • If hyperbaric chamber therapy helps autism
  • And hyperbaric chamber increases stem cell production
  • Then stem cells help Autism

http://clinicaltrials.gov/ct2/show/NCT00335790

3. Nonetheless, there is an excellent argument for the viability of stem cells to treat Autism.  Here is an exhaustive study gauging the potential of a clinical trial on the benefits of stem cells treating Autism: http://www.translational-medicine.com/content/5/1/30

4.  There is additional evidence that Stem Cells can treat Autism here: http://repairstemcell.wordpress.com/2009/10/01/autism-stem-cells-a-brief-history/

5.  Placebo/expectation effect:

Do stem cell treatments create a placebo/expectation effect?  Good question.  You can find the answer here: http://repairstemcell.wordpress.com/2009/10/12/the-stem-cell-placebo-effect/

6.  Clinic’s responsibility regarding claims of success:

Stem cell clinics must be up-front regarding the results of their therapy and unless you see this type of clear, open and honest disclaimer, I would be skeptical about going to a clinic: “We would like to point out from the start that there are still some questions concerning the function of stem cells that science has not yet been able to answer, and that despite the advances that have been made recently there is no guarantee for the success of stem cell therapy. Nevertheless, every week we see this new “medicine” helping a lot of people. Therefore, we offer therapies with adult stem cells whenever classical treatment does not yield the type of results that are satisfactory for the patient.”  In addition, this facility points out that only 70% of patients responded and they are up-front as to how they define improvement.  Personally, I would see this kind of clear definition of defining “improvement” than someone throwing out some empty and unsubstantiated claims.

7.  Costs of treatment:

Is it worth it?  Let’s put aside for the moment that “there is no price to great to secure your child’s health” because that does not factor in your financial situation and look at the comparative costs.

  1. Michael Ganz, an assistant Professor of Society, Human Development, and Health at Harvard School of Public Health, has examined the cost of autism for US society //and has found that the disease costs a person $3.2 million over the entire life span. – http://www.bio-medicine.org/medicine-news/The-Price-Of-Autism-9735-1/
  2. And “…a nearby school operated by the May Institute that practices behavior modification on its autistic students charges school districts $100,000 per year in tuition. And home-based ABA/behavior modification programs charge about $75,000 a year for 25 hours a week of therapy, supervision and team meetings. Parents have been known to remortgage their homes or go bankrupt in an attempt to fund these programs.” http://autismtomorrows.blogspot.com/2009/10/cost-effectiveness-and-autism-treatment.html

All the evidence and many, many patients treated successfully, reinforce that stem cells are a powerful and underutilized tool for Autism and Asperger’s patient recovery .

autism-ribbonautism-ribbonautism-ribbonautism-ribbonautism-ribbonautism-ribbon

Perez Hilton, Peta, Stem Cells

In CELEBRITIES & STEM CELLS on October 2, 2009 at 8:51 pm

http://static.open.salon.com/files/perez-hilton1240936589.jpgJO: You support PETA, which directly opposes biomedical HIV research; you also support HIV research and advocacy groups such as Keep A Child Alive. Do you personally oppose biomedical HIV research? Should the gay community support or oppose biomedical research?

PH: You know, it wouldn’t be fair to say I support PETA—it’d be fair to say I support some of the things they say, but at the same time, fuck—I eat meat and own some leather shoes. I don’t wear fur, though. You know, I’m a human being, and human beings are walking contradictions! I think we should explore all avenues for finding a cure for HIV and AIDS—and all diseases! Like stem cell research—I’m all for it!

via Perez Hilton: More from His Interview With Just Out.

‘No proof’ of benefit to children????

In ALL ARTICLES on September 23, 2009 at 11:26 am

The factual information is only half here and the conclusions are all wrong! My comments in red. -dg

No proof’ of benefit to children

By REBECCA TODD – The PressLast updated 05:00 23/09/2009

Stem-cell treatment is “highly experimental”, with “potential hazards“, the Paediatric Society of New Zealand warns.

Re: “highly experimental”
  • There have been thousands of adult/repair stem cell treatments with virtually no side effects and a significant proportion were successful.
Re: “potential hazards”
  • By not differentiating between the problematic embryonic stem cells with a history of causing tumors and the non-problematic adult stem cells with a history of treating people successfully, the author  effectively generalizes to the point of ridiculousness.  This is like saying: “all bacteria is bad.” (think pro-biotic and beneficial flora in the digetive tract)

… society president Rosemary Marks said the therapy (had) no controlled studies to back claims of dramatic improvements.

Re: “No controlled studies:”
  • 5,030 scholarly papers when you type “stem cell” and cerebral palsy into google’s scholarly papers
  • 2,572 clinical trials completed or in process when you type “stem cell” into clinicaltrials.gov (After “studies,” scientists perform even more rigorous clinical trials to back up their findings.)
  • 1,160,000 scholarly papers when you type “stem cell” into google’s scholarly papers

It said the stem-cell operation carried risks of introducing viral diseases or bacterial infections, and even malignant tumours developing after the transplant.

Re: “viral diseases, bacterial infections, malignant tumours”

  1. Any blood drawn that goes through a lab is at risk of “viral diseases or bacterial infections.”
  2. So too, any stem cell rich sample drawn that goes through a lab is at risk of “viral diseases or bacterial infections.”
  3. Evidence supports that the risk is the same for both and standard safe practice of lab protocols removes this risk almost entirely.
  4. ONLY embryonic stem cells have a history of creating tumors and malignant tumors.
  5. Adult stem cells have no history of generating tumors in thousands of studies, clinical trials and patients treated.

“…stem-cell treatment for children with cerebral palsy is unproven…

Re: “Unproven”

“Most centres offering this treatment also follow the treatment with intensive physical-therapy programmes,” the pamphlet said. “It is very difficult to know whether improvements are the result of the stem-cell treatment itself, or the intensive physical therapy, or are the result of the child growing and developing.”

Re: “It is very difficult to know whether improvements are the result of the stem-cell treatment itself, or the intensive physical therapy, or are the result of the child growing and developing.”

“…there was “no evidence” that using your own cord blood had benefits, he said.”

Re: “no evidence”
  • One stem cell center uses a treatment method involving any cord blood.  The cord blood does not have to be autologous or from the patient’s own body.  So far, it’s been effective in treating cerebral palsy with an 80 percent success rate in over 200 patients.
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