DAVID GRANOVSKY

Posts Tagged ‘BUBBLE’

BUBBLE BOY CURED WITH STEM CELLS

In ALL ARTICLES, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on February 11, 2009 at 11:15 pm

bubbles

BUBBLE BOY CURE

Associated Press Wire Feed ^ | June 27, 2002 | PAUL RECER

Posted on Thursday, June 27, 2002 3:53:16 PM by NYer

WASHINGTON (AP) _ A single injection of genetically modified stem cells is all it took to cure two children of a complex form of an inherited immune system disorder often referred to as the “bubble boy disease,” researchers report.

An experimental technique that altered genes in bone marrow stem cells restored the immune systems of the children, researchers from Italy and Israel said in a study appearing in the journal Science. The children were born with what experts said was the most complex form of severe combined immunodeficiency disorder, or SCID.

“Both children have been cured but … both will be closely followed to see how it develops in the future,” said Maria Grazia Roncarolo of the San Raffaele Telethon Institute for Gene Therapy in Milan, Italy. The children, who were seven months and 2 1/2 years old when the therapy began, were released with healthy, functioning immune systems between 15 months and 24 months ago, Roncarolo said in Milan.

via BUBBLE BOY CURE.

FIRST UK BUBBLE BOY CURED WITH STEM CELLS

In ALL ARTICLES, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on February 11, 2009 at 11:12 pm

bubble

Boy in ‘bubble’ cured of life-threatening disease

A seven-year-old boy kept in a “bubble” for two months has become the first person in Britain to be cured of a rare life-threatening disease with a bone marrow transplant.

By Caroline Gammell

Last Updated: 4:31PM BST 03 Jun 2008

Rhys Harris, boy in a ‘bubble’, cured of life-threatening disease

Rhys Harris Photo: WNS

Rhys Harris was kept in isolation in the airtight chamber while his immune system was destroyed by chemotherapy and replaced by being given new bone marrow.

During eight weeks of treatment, his parents had to wear specially sterilised gowns and, although they could dress and cuddle their son, they were not allowed to kiss him.

Rhys was initially diagnosed with a mycobacterial infection – a “cousin” of tuberculosis – which is rare.

When doctors investigated further, they discovered that he had an underlying immune deficiency disease called Nemo, Nuclear Factor Kappa B Essential Modulator, which effectively stopped his white cells working properly.

Less than 12 people in the UK currently have the condition.

Rhys, from Newbridge in South Wales, was transferred from care in Cardiff to Newcastle General Hospital, one of two units specialising in treating such diseases.

The transplant took place last October and this week his parents Kevin, 44, and Dawn, 39, were told the procedure had been successful.

Rhys, who was left deaf after suffering meningitis as a baby, now has a “normal” immune system and is no more at risk from disease and infection than anyone else.

Mr Harris said: “We knew it was a slim chance but we had to take it. The flipside of the coin just wasn’t worth thinking about.

“Rhys just went through hell and back and back to hell again – it was a really tough time for all of us. He is really tough and resilient. He is a normal seven year old boy apart from this who loves rugby and adores his brother.”

Dr Mario Abinun, consultant paediatric immunologist at Newcastle General Hospital, said 25 similar transplants were carried out each year.

“This is the first time this operation has been carried out on a child with Nemo in the UK. When Rhys came in he was a very sick boy but now he is so much better.

“All the staff at the hospital are happy and glad to see the little boy getting better and enjoying the normal things boys should be doing – running around and being mischievous.”

via Boy in ‘bubble’ cured of life-threatening disease – Telegraph.

FIRST EVER BUBBLE GIRL CURED IN 2002!

In ALL ARTICLES, STEM CELLS IN THE NEWS, VICTORIES & SUCCESS STORIES on February 11, 2009 at 11:11 pm

soap-bubble

New procedure brings hope to girl with ‘bubble boy disease’

By Jack Katzenell -Associated Press writer

Published: Wednesday, July 3, 2002 8:26 a.m. MDT

JERUSALEM — A 2-year-old Palestinian girl who spent much of her life in germ-free isolation met reporters Monday, showing off her functioning immune system, repaired by a new procedure that offers her and others with her disorder a normal life.

Taher and Hayyam Abu-Saed, a Palestinian couple from Jerusalem, had been childless for 10 years when their first son was born. He died soon after birth of a rare hereditary disease, severe combined immunodeficiency system, or SCID, often referred to as “bubble boy disease.”

Their second child, a girl, also had the condition, but she was cured thanks to a bone marrow transplant from a healthy baby brother.

When the couple learned that their fifth child, Salsabil, had SCID, there was no donor available for her. “We thought she was doomed,” Taher Abu-Saed told The Associated Press.

Yet a bright-eyed and healthy-looking Salsabil appeared with the pediatrician who treated her, and with scientists who developed the cure.

Salsabil was the first baby in the world to be cured of the most acute form of SCID by a new procedure developed in Israel and Italy, said Shmuel Slavin, head of the immunology department at Hadassah University Medical Center in Jerusalem.

Story continues below

Quantcast

Another child was cured by the same treatment shortly after at the San Raffaele Telethon Institute for Gene Therapy in Milan, which collaborated with Hadassah in developing the cure.

via Deseret News Archive | New procedure brings hope to girl with ‘bubble boy disease’.

Follow

Get every new post delivered to your Inbox.

Join 3,080 other followers

%d bloggers like this: