DAVID GRANOVSKY

Archive for November 15th, 2011|Daily archive page

EMBRYONICS’ BLEAK FUTURE AND BOTCHED PAST

In ALL ARTICLES on November 15, 2011 at 6:42 pm

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EMBRYONICS’ BLEAK FUTURE AND BOTCHED PAST

BLEAK FUTURE

I just received a comment from MB and despite Geron and the rest of the world abandoning embryonic stem cells for adult, he is still optimistic about the future of embryonic stem cells (with a little plug snuck in for a company he probably owns stock in).

My original comment:

embryonic research has been 100% fruitless (in regard to generating
treatments) for well-funded and government supported scientists around the world for the last 13 years.  Embryonic stem cells are the only significant obstacles to embryonic stem cell treatments.  Adult stem cells on the other hand have successfully treated 10s of thousands over the past decade.

MB’s response:

hESCs (human embryonic stem cells) have only been around for 13 years compared to adult stem cells 30+ years…. give it some time… human embryonic stem cells (especially ACT’s embryo SAFE blastomere-derived) will be THE GOLD standard :)  watch and SEEE the difference…soon..

My response:

MB – Not even close.   Embryonic stem cells have been around for way longer than since James Thompson and friends derived the first human embryonic stem cell line at the University of Wisconsin-Madison in 1998.

To clarify:

“Research in the human stem cell field grew out of findings by Canadian scientists Ernest A. McCulloch and James E. Till in the 1960s.”

1963: Becker AJ, McCulloch EA, Till JE (1963). “Cytological demonstration of the clonal nature of spleen colonies derived from transplanted mouse marrow cells”. Nature 197: 452-4. PMID 13970094.

1963: Siminovitch L, McCulloch EA, Till JE (1963). “The distribution of colony-forming cells among spleen colonies”. Journal of Cellular and Comparative Physiology 62: 327-36. PMID 14086156.

1978: Stem cells were discovered in human cord blood

1981: First in vitro stem cell line developed from mice

1981 – Mouse embryonic stem cells are derived from the inner cell mass

That’s 30 years ago!

Evans, M.J. & Kaufman, M. Establishment in culture of pluripotential stem cells from mouse embryos. Nature 292, 151–156 (1981).

1981 – Martin, G.R. Isolation of a pluripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc. Natl. Acad. Sci USA 78, 7634–7638 (1981).

1984 – Andrews, P.W. et al. Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Lab. Invest. 50, 147–162 (1984).

Blastomeres isolated from the ICM of mammalian embryos and grown in culture are known as embryonic stem (ES) cells. These pluripotent cells, when grown in a carefully coordinated media, can give rise to all three germ layers (ectoderm, endoderm, and mesoderm) of the adult body.

1986: Robertson, Elizabeth , et al. Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector. Nature 323, 445 – 448 (02 October 1986)

1988: Embryonic stem cell lines created from a hamster

1995: First embryonic stem cell line derived from a primate

1995: Thomson, J.A. et al. Isolation of a primate embryonic stem cell line. Proc. Natl. Acad. Sci. USA 92, 7844–7844 (1995).

And then we get to what MB considers the “discovery of embryonic stem cells”:

1998 – James Thomson and coworkers derive the first human embryonic stem cell line at the University of Wisconsin-Madison.

Not to worry, though MB.  Adult stem cells HAVE been used in bone marrow transplants for over 40 years so they still have the upper hand in “time we’ve worked with them.”  Then again, it was only in 1998 that adult stem cells were considered for treating other illnesses.

Just out of curiosity, besides

“embryonic stem cells have proven 100% fruitless (in regard to generating treatments) for well-funded and government supported scientists around the world for the last 13 years,”

how do you plan on addressing these other embryonic stem cell issues to name a few?

  1. they create cysts and tumors that can develop into cancer at the site of the injection and injury
  2. rejection issues require immunosuppressive drugs for the ill patient
  3. embryonic stem cells (and induced pluripotent stem cells) carry the genetic anomalies of the donor
  4. they have to date treated zero diseases successfully
  5. scientists probably need to cure cancer first to use them
MIRROR THE RESULTS

MIRROR THE RESULTS

But if MB can mirror the results of  the success rate of adult stem cell treatments (~65% of patients have significant improvement in their incurable, chronic or terminal illnesses) and do so without the side effects alluded to above (adult stem cells have virtually zero side effects except for sometimes additionally fixing more than the intended organ/illness) then I would love to hear about it!

CBS REPORTS: ADULT STEM CELL TREATMENTS WORK!

In ALL ARTICLES on November 15, 2011 at 1:23 pm
The king is dead, long live the king!
Embryonic stem cells are dead, long live Adult stem cells!

In early 2009 I wrote an article called “SCREW THE EMBRYOS, THEY’RE IRRELEVANT!

ANTHONY HOPKINS SAYS: "SCREW THE EMBRYOS!" (Legends of the Fall) :p

“…since few people can afford to travel outside the country for adult stem cell treatments, ESC-crazed America, the Bangladesh of stem cells, with its focus on “treatment useless” research, and 4-8 years behind the rest of the world (in 2009) on available adult stem cell treatments, has become exactly that, a death row prison cell for those suffering from so-called untreatable diseases.”

In “SCREW THE EMBRYOS”, I explained why Embryonic stem cells will not treat humans for decades.  I explained how embryonic research has been 100% fruitless (in regard to generating treatments) for well-funded and government supported scientists around the world for the last 13 years. I explained how Adult stem cells have been treating patients outside the USA for years and I shared what a tragic, terrible waste of life it is that Americans don’t know there are safe and effective treatment options for over 100 incurable diseases.

With Embryonic stem cell treatment research now an obvious waste of time, money and resources, where should the desperate patient with chronic or incurable disease turn?  Adult Stem Cells

Allow me to introduce you to Adult Stem Cells.

STEM CELLS 101 pic

STEM CELLS 101 – short

ADULT STEM CELL = ASC

  • SOURCE/DERIVED FROM – comes from blood, umbilical cords, bone marrow, placenta fat tissue, muscle, nasal neurological, breast milk, menstruation, dental pulp, and many more
  • PURPOSE IN BODY – they are the body’s natural healing cells
  • OBSTACLES+SIDE EFFECTS – ~zero problems (virtually zero side effects)
  • TREATMENT HISTORY – used in bone marrow transplants to treat cancer for 40 years
  • TREATMENT HISTORY – can currently treat 130+ diseases safely and effectively (CP, MS, Autism, Diabetes, CHF, PAD, etc)

To see if your condition can be treated with Adult stem cells, please fill out this form: http://bit.ly/PATIENTQUESTIONNAIRE

cbs logoCBS has been against Adult Stem Cells for years.  They repeatedly referred to the doctors and scientists involved in adult stem cell treatments as quacks, crooks, con-men and scam artists.  They refer to adult stem cell treatments as snake oil despite a record of safety and efficacy going back to 2002! At the same time, CBS has been promoting the ‘huge potential of embryonic stem cell treatments.’  I take no pleasure in the irony that the CBS “eye” has been completely blind to the benefits of Adult stem cells for years while the rest of the world touted their benefits and the rest of the world’s patients recovered from terminal, chronic and incurable illnesses while American patients had zero options for recovery.

For a history of stem cell treatments of heart disease going back to 2002 – http://repairstemcell.wordpress.com/heart-disease-treatment/

All of this has now changed.  CBS has done a 180 degree flip and are now advocates for the benefits of Adult stem cells!

CBS VIDEO on Adult Stem Cell Success with Heart Disease

CBS ARTICLE on Adult Stem Cell Success with Heart Disease

Clinical Trial in The Lancet CBS Based Their Reporting On

Irony number 2 is that CBS uses words like “breakthrough” and “first ever.”

http://www.techbostonacademy.org/staff/english/pisano/blog/wp-content/uploads/2008/11/irony6.jpg

Do you know there are 443 clinical trials at clinicaltrials.gov with the keywords “stem cell” and “cardiac?”  There is not a single one which is a completed Embryonic stem cell trial.  Point of fact, there is not a single completed Embryonic stem cell trial for any disease anywhere. There are over 2,000 completed Adult stem cell trials.

WOW PIC

Do you know there are 5,170 peer reviewed published studies with the keywords “adult stem cell” and “cardiac?”

MAJOR WOW FACTOR!

MAJOR WOW FACTOR!

With the death of Embryonic stem cell treatments and the RE-discovery of Adult stem cell treatments, don’t you owe it to yourself to see if Adult stem cells can help you?

To see if your condition can be treated with Adult stem cells,

please fill out this form: http://bit.ly/PATIENTQUESTIONNAIRE

A HISTORY OF THE GERON EMBRYONIC STEM CELL FIASCO

In BUSINESS OF STEM CELLS on November 15, 2011 at 1:27 am

http://geekcentricity.com/wp-content/uploads/2010/09/Fiasco.jpg

Embryonic stem cell treatment are now an unrealized potential.

Adult stem cell treatments are a realized potential.

To see if your condition can be treated with Adult stem cells, please fill out this form: http://bit.ly/PATIENTQUESTIONNAIRE

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