DAVID GRANOVSKY

Archive for February 10th, 2011|Daily archive page

STEM CELLS FOR RECONSTRUCTIVE + PLASTIC SURGERY

In VICTORIES & SUCCESS STORIES on February 10, 2011 at 8:54 pm

Maxillary and mandibular radionecrosis (stage IIIR) with pathologic fracture presented early osteogenesis:

  • total recovery from alveolar nerve anesthesia, facial nerve reinnervation, and skin regeneration.
  • nonhealed fracture, bone loss, and bilateral paresthesia demonstrated callus formation, bone regeneration, and nerve recovery.
  • maxillary bone regenerated after massive deficiency
  • oral functional restoration with implants and fixed prosthesis was accomplished in all cases

Plast Reconstr Surg. 2010 Nov;126(5):1699-709.
Regenerative facial reconstruction of terminal stage osteoradionecrosis and other advanced craniofacial diseases with adult cultured stem and progenitor cells. – Mendonça JJ, Juiz-Lopez P.

Lugo, Spain From the Head and Neck Surgery Unit, POLUSA Hospital.

Abstract
BACKGROUND: Treatment options in cases of severe craniofacial disorders with bone loss and tissue damage are usually limited to vascularized and nonvascularized tissue transfers, allografts, mechanical devices and, more recently, facial transplantation. Despite the therapies available, the demand for new approaches is realized in cases where current therapies are unable to resume form and function. This study presents the feasibility of alternative treatments based on cultured bone marrow cells that yield mixed populations of mesenchymal, hematopoietic, and endothelial lineages at very early stages implemented as part of a novel regenerative procedure.

METHODS: One hundred milliliters of a bone marrow aspirate was inoculated into the automated single-pass perfusion technology system, AastromReplicell, for the development of the cellular product, tissue repair cells. After 12 days of incubation, cells were exposed to a specially designed osteogenic environment in an autogenous fibrin-rich and platelet-rich clot and membrane with a mineral base of ?-tricalcium phosphate and hydroxyapatite.

RESULTS: A case of maxillary and mandibular radionecrosis (stage IIIR) with pathologic fracture presented early osteogenesis, total recovery from alveolar nerve anesthesia, facial nerve reinnervation, and skin regeneration. Another case with nonhealed fracture, bone loss, and bilateral paresthesia demonstrated callus formation, bone regeneration, and nerve recovery. Finally, maxillary bone regenerated after massive deficiency. Oral functional restoration with implants and fixed prosthesis was accomplished in all cases.

CONCLUSION: After nerve, bone, skin, and vessel formation in three patients with severe abnormality, bone marrow-derived mixed cultured stem cell lineages could be considered a new paradigmatic approach to advanced disease.

AUTISM/ASPERGER’S + STEM CELLS

In VICTORIES & SUCCESS STORIES on February 10, 2011 at 9:41 am

A friend asked:

when are they going to allow us to use stem cells for autism in this country??? I am getting impatient every treatment center I’ve called here (in the US) says they wont do it! I am having a baby in feb and want to use the cord blood for my son but when will I ever be able to? anyone know?

WHY NO STEM CELLS IN THE US (FOR AUTISM)? – http://repairstemcell.wordpress.com/why-no-stem-cells-in-the-us/

STEM CELLS FOR AUTISM – PROGRESS TO DATE – http://repairstemcell.wordpress.com/2009/10/26/stem-cells-for-autism/

POTENTIAL OF STEM CELL TREATMENTS FOR AUTISM – http://repairstemcell.wordpress.com/2009/10/16/potential-of-stem-cell-treatments-for-autism/

TREATMENTS AVAILABLE TODAY – Asperger’s is an Autism Spectrum Disorder.  To see if you or your loved one might be a candidate for Stem Cell Therapy, contact me at dsgrano@gmail.com

CDC VACCINE COVER UP – MERCURY ACTUALLY DOES CAUSE AUTISM? Central Figure in CDC Vaccine Cover-Up Absconds With $2M

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