DAVID GRANOVSKY

Archive for September, 2010|Monthly archive page

THE WHOLE IS GREATER THAN THE SUM OF THE PARTS

In OFF THE BEATEN PATH on September 28, 2010 at 7:53 pm

Completely random, caffeine infused, unedited rant

(not really random, actually in response to this comment on facebook:

” Breaking news: Alzheimer’s is a whole body disease. Insulin, glucose, neurological system + nutrition all affect it. Breaking news? So…the entire body works holistically…diseases should be treated holistically? This is only breaking news in USA now, it was breaking news in Asia + India 3,000 years ago. Western med …always seems look through the wrong end of the binoculars + try to kill a fly with a shot gun.”

alexgrey33ri.gif alex grey image by breando

THE WHOLE IS GREATER THAN THE SUM OF THE PARTS

As I spend time with specialists I find more and more of them are either realizing or “able to empirically prove” that diabetes, Alzheimer’s, Parkinson’s, etc etc are a disease of the entire body. The evidence is all there.

SO the drugs that target a single chemical interaction, a single organ, a single anything…even if they work, will not fix the body, they will only fix that specific problem. So then 6-12 months later when that part is no longer screaming for fixing and the next part makes itself heard, you will then take a new drug in Act 2 of “my whole body is broken but I am going to treat it one problem at a time.”

Segue to car analogy: Go put 100,000 miles on your car. Don’t change the oil, don’t fill the tires, don’t put fuel line cleaner in the gas tank, don’t maintain it all. Wait until it is smoking, shaking, coughing and stalling. Wait until every turn produces squeals of protest from the tie rods, axle, wheels and steering column. Wait until every hill cause it to wheeze, belch smoke, shudder and shake. Then and only then, go out and buy your self a brand new carburetor or exhaust, or fuel injector. In fact, you can buy any one thing, brand new and replace it. Any one thing but just one thing. Then question why your car doesn’t drive like when it was new.

Now back to the movie analogy – Act 2 of “my whole body is broken and I am going to treat it one problem at a time.” ……… Now here’s the fun part. Act 2 assessment – problem 1 (antagonist #1) is fixed via drug #1 (savior #1), problem 2 (antagonist #2) enters the scene and drug #2 (savior #2) is introduced to quell problem #2…but as in all dramas, drug #1 (savior #1) is not so pure of heart. This hero is flawed and now there is a new problem (antagonist #3) generated by the introduction of savior #1. And so on and so on. COnfusing? Depressing? You’re damn right! Now here’s the b*tch of it…this tragic movie will go on for the rest of your life.

Here’s an interesting analogy: I envision the plot as a snake eating it’s own tail. The more he eats, the less hungry he is and the less body he has to sustain…but the more he eats, the more he is using up his own body…until when he has finally eaten himself all the way from tail to head, there is nothing left to sustain but there is also nothing left of his body. If this isn’t clear, feel free to go to the chemo or radiation ward. I think the analogy will absolutely be clear as day to you then.

And please understand that I truly mean no disrespect to these docs and scientists who are calling attention to the fact that diseases, once believed to be isolated events in the body; are actually system wide organisms within an organism and through circulation, electric-neurological exchange or associative influence actually interact with every other cell in your body. These docs and scientists who through empirical western analysis are trying to draw attention to a holistic approach of treatment are lone forces crying out for change in an industry of rigidity…they are often the sole open minded wise person in a forest full of old rooted dead trees…they are working in a centuries old system that is anti-free thought, anti- radical concept and anti “anything that challenges the status quo.”

These docs and scientists who are challenging their industry thinking deserve our support. They need our help to get the word out and more importantly, we as patients have a responsibility to ourselves and our loved ones to question what else is out there, what else is involved in this problem, what other factors are contributing to my illness. So do it!

…and that’s my rant.

Big Pharma Scores Big Win: Medicinal Herbs Will Disappear in EU

In BUSINESS OF STEM CELLS on September 24, 2010 at 1:31 am

Big Pharma Scores Big Win: Medicinal Herbs Will Disappear in EU

It’s almost a done deal. We are about to see herbal preparations disappear, and the ability of herbalists to prescribe them will also be lost.

by Heidi Stevenson – 12 September 2010

Big Pharma has almost reached the finish line of its decades-long battle to wipe out all competition. As of 1 April 2011—less than eight months from now—virtually all medicinal herbs will become illegal in the European Union. The approach in the United States is a bit different, but it’s having the same devastating effect. The people have become nothing more than sinks for whatever swill Big Pharma and Agribusiness choose to send our way, and we have no option but to pay whatever rates they want.

Big Pharma and Agribusiness have almost completed their march to take over every aspect of health, from the food we eat to the way we care for ourselves when we’re ill. Have no doubt about it: this takeover will steal what health remains to us…

via Big Pharma Scores Big Win: Medicinal Herbs Will Disappear in EU.

Heart study finds long-term value in stem cell treatments – FierceBiotech Research

In STEM CELLS IN THE NEWS on September 22, 2010 at 8:17 pm

Heart study finds long-term value in stem cell treatments

August 31, 2010 — 8:10am ET | By John Carroll

Related Stories

* Adult stem cells key to ventricle transplants

* Osiris reports major gains in stem cell trial

* Heart researchers hunt for drugs that rein in mystery protein

* Researchers combat aging as a “stem cell disease”

* iPSC use may be limited by ‘memory’

* Artificial artery readied for human trials

* Stem cell patch developed to repair damaged hearts

* Cell discovery opens new door to heart researchers

* Revolutionary stem cell trials planned in the UK

* Researchers testing stem cell therapy for CHF

German scientists have posted some of the most convincing long-term data yet seen demonstrating that injections of a chronic heart failure patient’s own bone marrow stem cells can significantly improve heart function and raise their chances of survival.

The researchers recruited close to 400 subjects for the trial, nearly evenly dividing them between a group that received stem cell injections and another group which opted to go without the added therapy. Researchers said they could begin tracking a positive response after three months and found that after five years only seven of the stem cell treatment group had died compared to 32 in the control arm of the study. All of the patients were provided standard therapy for their condition.

“Our study suggests that, when administered as an alternative or in addition to conventional therapy, bone marrow cell therapy can improve quality of life, increase ventricular performance and increase survival,” said lead researcher Bodo-Eckehard Strauer of Duesseldorf’s Heinrich Heine University. And Strauer went on to tell a gathering in Stockholm that the therapy presents no risks and “can only be beneficial.”

Not everyone who has reviewed the data, though, is so certain. “God gave us two gifts for doing clinical research–blinding and randomization,” Rob Califf, vice chancellor for research at Duke University, told MedPage Today. “If you have done neither, your data are interesting but not definitive.”

via Heart study finds long-term value in stem cell treatments – FierceBiotech Research.

Minnesota cancer researchers net $26M for stem cell therapies « MedCity News

In STEM CELLS IN THE NEWS on September 21, 2010 at 8:22 pm

Minnesota cancer researchers net $26M for stem cell therapies

Two researchers at the University of Minnesota‘s Masonic Cancer Center will receive $26 million in renewed grants from the National Cancer Institute to boost stem cell therapies that treat blood and bone cancers, as well as other disorders.

Dr. Philip McGlave and Dr. Jeffrey Miller want to increase the availability, safety and effectiveness of hematopoietic stem cell transplants and cell therapies to improve treatment and survival for thousand of patients diagnosed each year with leukemia, lymphoma, multiple myeloma and other blood and bone marrow disorders.

McGlave and his research team will get $12.6 million to improve stem cell transplant and cell-based treatments. McGlave is deputy director of the Masonic Cancer Center and director of the University Medical School’s Division of Hematology, Oncology and Transplantation.

Miller will get about $13.3 million to continue his team’s research on characterizing “natural killer cells” or “NK cells” to reduce the rate of relapse of leukemia after stem cell transplants. He is associate director of the Masonic Cancer Center’s Experimental Therapeutics Program and professor of medicine focusing on hematology, oncology and transplantation.

via Minnesota cancer researchers net $26M for stem cell therapies « MedCity News.

Autologous Neural Stem Cells Benefit Parkinson’s Patients – AdultStemCell.com

In STEM CELLS IN THE NEWS on September 21, 2010 at 8:21 pm

Autologous Neural Stem Cells Benefit Parkinson’s Patients

Stem cells and stem cell research have long been studied to help provide relief of symptoms and potential cures for neurodegenerative diseases such as Parkinson’s disease.

The use of adult stem cell therapy has grown in popularity, surpassing even traditional embryonic stem cell research methodology is. Autologous stem cells are those harvested from individual patients suffering from a disease process such as Parkinson’s, which do not carry with them the risk of rejection, as do organs or cells transplanted from other individuals into that patient.

Stem Cell Treatment Studies

Adult stem cells are known as undifferentiated or multipotent cells capable of producing different blood cells. That means that they haven’t specifically developed or grown into a specific type of tissue or organ. Adult stem cells can renew themselves and grow into become just about any type of specialized cell, tissue or organ tissue.

Neural stem cells are multipotent cells that self-renew or self generate. Neural stem cells that may be generated from a patient’s own bone marrow or nerve tissues may be used to treat a variety of traumatic brain injuries, damage caused by strokes, or neuro-genetic disease processes such as those commonly found in Parkinson’s or Alzheimer’s disease patients.

Neural stem cells may be harvested from the bone marrow as well as various areas of the brain and central nervous system. Recent studies, including those described in The Open Stem Cell Journal 1, 20-29, February 2009 stated that autologous adult stem cells were able to relieve Parkinson’s patient symptoms for almost five years.

Stem cells 24, 781-792, March 2006, reported that the use of stem cells derived from umbilical cord stem cells and used to treat rats with Parkinson’s determined “significant recovery in motion and behavior”.

In Japan, researchers from Kyoto University successfully treated mice with Parkinson’s disease by transplanting “nerve cells developed from their own bone marrow stromal cells.” Journal Of Clinical Investigation 113: 1701-1710, 2004

Research and technology regarding the use of autologous neural stem cells to treat symptoms of Parkinson’s disease, improve mobility and quality of life for patients continue around the world. Individuals from the United States, as well as Parkinson’s patients from around the world, increasingly travel to destinations such as Mexico, the Ukraine, South Korea, Asia, and South America for promising stem cell treatments.

via Autologous Neural Stem Cells Benefit Parkinson’s Patients – AdultStemCell.com.

STROKE articles:

  1. http://repairstemcell.wordpress.com/2010/09/21/autologous-neural-stem-cells-benefit-parkinson%e2%80%99s-patients-adultstemcell-com/
  2. http://repairstemcell.wordpress.com/2010/09/20/stem-cell-treatment-for-stroke-and-traumatic-brain-injury-wholewellness-net/
  3. http://www.scientificamerican.com/article.cfm?id=can-stem-cells-block-stroke-damage
  4. http://www.sciencedaily.com/releases/2011/08/110831160216.htm

Sacramento Bee — Weed Wars

In Medical Marijuana on September 21, 2010 at 8:04 pm

September 21, 2010

Capitol marijuana debate offers parallel universes for Prop 19

A state Capitol hearing today on how Proposition 19 may affect the future universe of California produced such disparate views that Assemblyman Tom Ammiano pondered the potential outcomes as perhaps only he can.

“A drug czar today could be on Dancing With the Stars tomorrow,” he said.

It was a light moment in a otherwise serious discussion over how California and its local governments will be impacted if voters pass the initiative to legalize marijuana for recreational use, permit small residential cultivation and allow cities and counties to tax and regulate retail pot sales.

On one side of the argument was Sacramento County District Attorney Jan Scully. Speaking on behalf of the California District Attorneys Association, she argued that the measure would do little or nothing to combat crime and would create an utter morass for local municipalities.

“It will not impede the drug cartels that are coming across our border and actually growing on our state and federal lands,” Scully told the joint legislative public safety committee hearing chaired by Ammiano and state Sen. Mark Leno, two San Francisco lawmakers and Prop 19 supporters.

Scully also argued that local governments will be flummoxed by the vagueness of the initiative. And she said the measure “will be so fraught with litigation over its merits…it will take years to ever take effect.”

But Prop 19 campaign spokeswoman Dale Sky Jones argued that California’s initiative will bring about changes mirroring the end of alcohol prohibition if passed.

“This is the first step to take control away from the criminals,” she said, adding: “We don’t have illegal grape-growing cartels in our national forests. And they don’t take out guns. They take out advertising.”

Jones also argued that the flexibility of the measure in allowing local governments to decide whether or not to allow retail pot operations – and determine how to tax them – is a plus.

“I’m not concerned about the patchwork,” she said. “Our cities and counties do many things on the local level quite successfully.”

Rand Corp researcher Beau Kilmer reiterated findings of the think tank’s recent study, declaring that California marijuana prices could plummet by 80 percent if Proposition 19 passed. Kilmer also said marijuana use could go up by between 50 and 100 percent.

At maximum use, he said, “We would be back to where we were in the 1970s.”

via Sacramento Bee — Weed Wars.

The Associated Press: Medical pot advocates oppose Calif. legalization

In Medical Marijuana on September 21, 2010 at 7:53 pm

Medical pot advocates oppose Calif. legalization

By ROBIN HINDERY (AP) – 1 hour ago

SACRAMENTO, Calif. — A coalition of medical marijuana advocates came out Tuesday against a California ballot initiative that would legalize the drug for recreational use and tax its sales.

Proposition 19 would inadvertently harm the most vulnerable patients by allowing local governments to prohibit the sale and purchase of marijuana in their jurisdictions, California Cannabis Association members said.

At a gathering outside the Capitol, the group predicted many cities and counties would impose such bans if voters approve the initiative, leaving local medical marijuana users with few options.

“The people who would be most affected are the sick, the elderly — patients who cannot grow their own and cannot travel to pick up a prescription,” said Amir Daliri, president of Cascade Wellness Center, a medical marijuana dispensary north of Chico.

Supporters of Proposition 19 said it explicitly protects the rights of patients and would provide them with safer and easier access to the drug by creating a strictly controlled, clearly defined legal system for pot cultivation, distribution and sales.

“Proposition 19 is actually going to further clarify that sales of medical cannabis are legal in this state,” said Dale Sky Jones, a spokeswoman for the Yes on 19 campaign. “The intent of our law is to protect medical cannabis patients and their rights.”

If Proposition 19 passes in November, California would become the first state to legalize and regulate recreational pot use. Adults could possess up to one ounce of the drug.

Supporters have targeted two areas of concern for voters: the economy and crime. Legalized pot would bring much-needed revenue to the state and reduce the influence of drug cartels, they said.

The measure was endorsed Tuesday by the largest labor union in the state. The Service Employees International Union, which has 700,000 members, said revenue generated by the initiative would help California preserve jobs and avoid cuts to key services such as education and health care.

The union represents workers in health care, building services and state and local government.

Critics question the economic effects and contend the initiative will simply serve to boost marijuana usage and drug-related crimes.

A Field Poll released in July found 48 percent of likely voters opposed the measure, while 44 percent supported it.

via The Associated Press: Medical pot advocates oppose Calif. legalization.

Medical marijuana user charged with growing plants in yard | detnews.com | The Detroit News

In Medical Marijuana on September 21, 2010 at 7:31 pm

Medical marijuana user charged with growing plants in yard

Mike Martindale / The Detroit News

Auburn Hills — A 43-year-old medical marijuana card holder was charged Thursday with violating state law by illegally growing plants in the back yard of his home and within 1,000 feet of an elementary school.

Mark Alan Rowe of Auburn Hills is charged with one count of manufacturing the controlled substance of marijuana in connection with a search warrant executed Wednesday at his home on Caroline Street. The offense is a felony punishable by up to four years in prison and a $20,000 fine.

Rowe, who was released on $10,000 personal bond, holds a valid Michigan Department of Community Health medical marijuana patient ID card.

Auburn Hills Lt. Casimir Miarka said police received a tip Tuesday that marijuana was being grown in Rowe’s back yard and officers confiscated 12 plants from the yard, which has a four-foot high chain link fence.

“If he had the plants growing inside his house and secure, we wouldn’t be having this conversation because he does have a card,” Miarka said. “But I don’t think out in the open qualifies under the law.”

Miarka said some plants were more than six feet tall.

Police said under Michigan Department of Community Health administration rules, a qualifying patient can keep 12 plants in an enclosed, locked facility, defined as a “closet, room, or other enclosed area equipped with locks or other security devices that permit access only by a registered primary caregiver or registered qualifying patient.”

Rowe could not be reached for comment Thursday.

via Medical marijuana user charged with growing plants in yard | detnews.com | The Detroit News.

Cannabis Medical Solutions Begins Roll Out of MediPayment(TM) Card to 150 Medical Marijuana Dispensaries in Colorado – MarketWatch

In ALL ARTICLES on September 21, 2010 at 7:30 pm

Cannabis Medical Solutions Begins Roll Out of MediPayment(TM) Card to 150 Medical Marijuana Dispensaries in Colorado

LOS ANGELES, Sep 21, 2010 (GlobeNewswire via COMTEX) –

Cannabis Medical Solutions Inc. (http://www.cannabismedsolutions.com/) /quotes/comstock/11k!cmsi (CMSI 0.02, +0.00, +15.00%) , a leading company specializing in merchant payment solutions and financial security products for medical marijuana dispensaries and high-risk merchant accounts, today announced that the Company has begun the roll out of its’ Proprietary MediPayment (TM) Card to over one-hundred and fifty medical marijuana dispensaries and compassionate care centers throughout the state of Colorado.

The CMSI proprietary “MediPayment” closed loop payment system will allow both dispensaries and their patients to utilize an alternative payment method other than cash and high rate credit card transactions, with complete tracking, real time transactions and SMS text messaging capabilities to the patients for availability of prescription medication.

“MediPayment(TM) is the first intelligent and secure transaction option available to medical dispensaries for purchase of medicine and products, eliminating the need for cash only and costly credit card transactions. We intend for Colorado to become a major proving ground and revenue model for our MediPayment(TM) system allowing patients the convenience of no longer needing to carry cash or to use high rate credit cards, while receiving tracking records and bonus rewards for their purchases,” stated Michael Friedman, CEO for Cannabis Medical Solutions.

via Cannabis Medical Solutions Begins Roll Out of MediPayment(TM) Card to 150 Medical Marijuana Dispensaries in Colorado – MarketWatch.

Stem Cell Treatment for Stroke and Traumatic Brain Injury | WholeWellness.net

In STEM CELLS IN THE NEWS on September 20, 2010 at 8:17 pm

Stem Cell Treatment for Stroke and Traumatic Brain Injury

September 20, 2010, By admin

Damage and Disability caused by Stroke

At present, ischemic stroke is the third leading cause of death in industrialised countries. With an annual incidence of 250–400 in 100 000 inhabitants, around 1 million people suffer from a stroke each year in the United States and in the European Union(1). Approximately a third of cases are left with some form of permanent impairment, making stroke the single largest cause of severe disability in the developed world.

Stroke is caused by the interruption of blood flow in a brain-supplying artery; commonly an embolus causes an occlusion (blockage) in the blood vessel. Ischemic stroke (cerebral infarction) and the even more devastating intracerebral haemorrhage, cause a disturbance of neuronal circuitry and disruption of the blood-brain-barrier that can lead to functional disabilities. At this time, therapy is primarily based on the prevention of recurrent (secondary) strokes. Rehabilitation therapy is important for maximizing functional recovery in the early phase after stroke, but once recovery has plateaued there is no known treatment.

Stem cell treatment could be the major breakthrough in effecting repair of some of the damage caused by stroke.

via Stem Cell Treatment for Stroke and Traumatic Brain Injury | WholeWellness.net.

Other STROKE articles:

  1. http://repairstemcell.wordpress.com/2010/09/21/autologous-neural-stem-cells-benefit-parkinson%e2%80%99s-patients-adultstemcell-com/
  2. http://repairstemcell.wordpress.com/2010/09/20/stem-cell-treatment-for-stroke-and-traumatic-brain-injury-wholewellness-net/
  3. http://www.scientificamerican.com/article.cfm?id=can-stem-cells-block-stroke-damage
  4. http://www.sciencedaily.com/releases/2011/08/110831160216.htm
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