Heart Muscle Health Aspects | VesCell adult stem cell therapy

Heart Muscle Health Aspects You Should Consider

Stunned or Dying Tissue can be Rejuvenated by Adult Stem Cells Injected in the Patient’s Heart

Click here to see if your heart disease is treatable with Adult/Repair Stem Cells now

James Eilert, a young man, who was a victim of the heart disease epidemic that is increasingly taking hold around the world, has been given a second chance at a healthy life thanks to VesCell adult stem cell therapy.

In 2006, at the relatively young age of 34, James experienced a major heart attack. His left anterior descending artery (or what the doctors call the ‘widowmaker’) was 100% blocked. The heart attack left him with severe damage to his heart. A normal ejection fraction is generally considered to be 55-75%. At the tender age of 34, James’ ejection fraction had sunk to 20-25%. The doctors diagnosed him as being in Class III NYHA Heart Failure.

He didn’t want to die, but figured dying would be a better option than living as he was. That was when James stumbled upon VesCell on the internet. Already a patient at the world renowned Henry Ford Heart and Vascular Institute in Detroit, James was shocked to find out that Dr. Barbara Czerska, the Medical Director of the Heart Failure Transplant Program at Henry Ford was featured prominently on the VesCell website. That, along with reading that recent medical research indicates that dead heart tissue can be ‘awakened’ by the implantation of adult stem cells gave James new hope.

He contacted VesCell and Dr. Czerska and prepared for his trip to Bangkok, Thailand to receive a new shot of hope using his own adult stem cells.

After arrival in Bangkok, James along with his father, were well taken care of by the TheraVitae team and the doctors and nurses at Phyathai 2 Hospital. James was treated by Dr. Damras Tresukosol, the director of the Phyathai-Harvard Heart Center and also the lead investigator of TheraVitae’s clinical trial using adult stem cells which was presented at the American Heart Association annual meeting in 2006.

Treated on November 14, 2007, James received 41 million of his own adult stem cells via catheter to heal his damaged heart muscle.

Told by doctors that the stem cells would take approximately 6-8 weeks to take affect, James was pleasantly surprised that the doctors were mistaken – just 1½ weeks after his stem cell treatment,

James had an echocardiogram done and found out his previously dead part of his heart had life again….

Click [HERE] to see if your heart disease is treatable with Adult/Repair Stem Cells now

via Heart Muscle Health Aspects | VesCell adult stem cell therapy.

NIH STARTS TO CATCH UP TO HEART DISEASE and STEM CELL TREATMENTS

For more info on clinical trials for treatment of heart disease, go HERE!

In the research laboratory, investigators often use a mouse or rat model of a heart attack to study new therapies (see Figure 9.1. Rodent Model of Myocardial Infarction). To create a heart attack in a mouse or rat, a ligature is placed around a major blood vessel serving the heart muscle, thereby depriving the cardiomyocytes of their oxygen and nutrient supplies. During the past year, researchers using such models have made several key discoveries that kindled interest in the application of adult stem cells to heart muscle repair in animal models of heart disease…

A second study, by Jackson et al. [3], demonstrated that cardiac tissue can be regenerated in the mouse heart attack model through the introduction of adult stem cells from mouse bone marrow. In this model, investigators purified a “side population” of hematopoietic stem cells from a genetically altered mouse strain. These cells were then transplanted into the marrow of lethally irradiated mice approximately 10 weeks before the recipient mice were subjected to heart attack via the tying off of a different major heart blood vessel, the left anterior descending (LAD) coronary artery. At two to four weeks after the induced cardiac injury, the survival rate was 26 percent. As with the study by Orlic et al., analysis of the region surrounding the damaged tissue in surviving mice showed the presence of donor-derived cardiomyocytes and endothelial cells. Thus, the mouse hematopoietic stem cells transplanted into the bone marrow had responded to signals in the injured heart, migrated to the border region of the damaged area, and differentiated into several types of tissue needed for cardiac repair. This study suggests that mouse hematopoietic stem cells may be delivered to the heart through bone marrow transplantation as well as through direct injection into the cardiac tissue, thus providing another possible therapeutic strategy for regenerating injured cardiac tissue.

More evidence for potential stem cell-based therapies for heart disease is provided by a study that showed that human adult stem cells taken from the bone marrow are capable of giving rise to vascular endothelial cells when transplanted into rats [6]. As in the Jackson study, these researchers induced a heart attack by tying off the LAD coronary artery. They took great care to identify a population of human hematopoietic stem cells that give rise to new blood vessels. These stem cells demonstrate plasticity meaning that they become cell types that they would not normally be. The cells were used to form new blood vessels in the damaged area of the rats’ hearts and to encourage proliferation of preexisting vasculature following the experimental heart attack.

Like the mouse stem cells, these human hematopoietic stem cells can be induced under the appropriate culture conditions to differentiate into numerous tissue types, including cardiac muscle [10] (see Figure 9.2. Heart Muscle Repair with Adult Stem Cells). When injected into the bloodstream leading to the damaged rat heart, these cells prevented the death of hypertrophied or thickened but otherwise viable myocardial cells and reduced progressive formation of collagen fibers and scars. Control rats that underwent surgery with an intact LAD coronary artery, as well as LAD-ligated rats injected with saline or control cells, did not demonstrate an increase in the number of blood vessels. Furthermore, the hematopoietic cells could be identified on the basis of highly specific cell markers that differentiate them from cardiomyocyte precursor cells, enabling the cells to be used alone or in conjunction with myocyte-regeneration strategies or pharmacological therapies. (For more about stem cell markers see Appendix E.i. How Do Researchers Use Markers to Identify Stem Cells?)

For more info on clinical trials for treatment of heart disease, go HERE!

more from NIH…

FIBROMYALGIA and STEM CELL TREATMENT

My Stem Cell Story

My name is E.A. I live in California. I’m 77 years old…After 45 years in the health care industry I have come to the conclusion that not only are the average American medical services substandard in quality and effectiveness but with overutilization of the current reimbursement system it tends to be from the patients perspective the best medicine in the world until they are exposed to the best medicine in the world.

I was developing, with USC School of Medicine, a neurological hospital in Beijing, when by chance I was introduced to what I considered the medical miracles of Korea…not because American physicians and medical schools can not do as well in providing high quality medical services, but because our systems are based upon the German medical training where the interns and residents are actively involved in the medical procedures in the surgery suites and the diagnostic area. In Korea they are criticized for not allowing the residents to do the major part of very complicated surgeries such as gamma knife, liver transplants, or even something as simple as kidney transplants.

After discovering this new world of medicine I decided to use my own body to investigate the potential for de-aging. After completing an extensive CT, MRI and PET physical at Seoul National University Hospital and having a complete evaluation from top to bottom I discovered the research they were doing with stem cells. In looking at my own health challenges I decided to do a 365 day blog reporting each day how effective the research in adult stem cells has grown to the point at which it is truly possible to effect real change and help in a very short period of time.

Ten months ago we produced a reality TV show demonstrating how a man aged 77 could be 67. The name of the show is “10 Years Younger” (Please check out web site for a link to the TV show). The procedures involved plastic surgery and dental implants. I have discovered that with adult stem cells, through technology developed by the scientists who cloned the first dog and won the Korean Science Award in 2008, that I do not have to settle for my various diseases and health conditions. The changes that were brought about for the TV show, were external, making me look 10 years younger, but with stem cells, the changes are internal, including a cardiovascular make over, etc., which has the potential of making me effectivley 20 years younger.

My Current Health Status (prior to adult stem cell treatment):
-40% closed aorta…plaque
-excess fat around liver
-20 lbs overweight

According to the VA in Los Angeles I suffer from
-Anemia
-Mid level pain from fibromyalgia
-Skin Cancer
-Hypertension
-High Cholesterol
-PSA of 7.8
-Enlarged Prostate

These conditions have affected my current physical activies as follows:
-No Dancing
-No free weights
-reduced travel schedule
-waking 5-6 times per night with pain
-muscle atrophy

Compared to 1 year ago when I was:
-traveling 12 international flights per year/10 domestic flights
-walking/jogging 5 miles daily
-working out with weights 3 days per wk
-dancing 2 times per week

My goal is to get back to where I was a year ago or more.

In May 2009 I had 5 cc’s of fat removed from tummy fat which was sent to Maryland where the stem cells were separated from the fat cells. The stem cells were sent to the stem cell bank where they were frozen to -196 Celsius degrees. One month ago they grew my stem cells to over 400 million and implanted 100 million directly into my face and 200 million in my arm intravenously on August 24th….follow my progress toward my goal of having a body that is effectively 20 years younger than my 77 years of living.

August 24th-Stem cells implanted with a minimum of discomfort no different than the many times I’ve donated blood to the blood bank. The stem cells implanted in my face were very similar to a very sharp pinch. Not painful, but with a minimal level of discomfort…tolerable.

August 25th-Returned to Seoul feeling no adverse effect and no relief from the stem cell injections

August 26th-Flew back to Los Angeles on business class and was able to sleep better than I had in many months with the roar of the engines and people moving all around. Arrived US at LAX still not feeling any relief for the fibromyalgia or from my hypertension reading. I had difficulty removing my bags from the overhead bin on the airplane. I had low muscle strength.

August 27th-Still no relief, substantial jet lag, and a great deal of trouble sleeping but not as tired as I’d been before when returning from Asia.

August 28th-No improvement but hoping that something would happen soon very similar to John Cullison’s experience after just a few days of his first treatment.

August 29th-Sleeping better, not as stressed but no improvement. Taking a lot of medication for my fibromyalgia.

August 30th-Feeling better but nothing dramatic that I could measure in reference to my fibromyalgia.

August 31st-Feeling better but don’t know if it’s just jet lag going away but pain in my neck, arms, legs and hips still substantial. Taking heavy doses of Tylenol.

September 1st-Getting out of bed in the morning I noticed that the pain in my shoulders has disappated during the night. I’m almost pain free. Woke up only four times during the night. Went dancing tonight!!! No discomfort!

September 2nd- Neck no longer painful. Shoulders normal. Pillow that I was using in my automobile no longer needed. Hip pain almost all gone. Went dancing again! Did I ever cut the rug!!!

September 3rd-Pain in my legs very minimal and almost completely gone were the typical signs of fibromyalgia. The only thing I can hope is that the stem cells are also doing a good job on my prostate and heart.

September 4th-Drove to Palm Springs with virtually no discomfort in my neck, arms, legs, and hips. Woke up only one time last night with no real discomfort at all.

It seems to be somewhat of a miracle to me.

.

.

Click [HERE] to see if your condition can be treated with Adult/Repair Stem Cells now.

 

Source

Antidisestablishmentstemcellianism

Antidisestablishmentstemcellianism – in opposition to proposals for the disestablishment of the pursuit of adult stem cells as the gold standard for treatment of disease…and the focus on embryonic stem cell research due to twisted concepts and agendas of state and government

Example:

The public has voiced their position of antidisestablishmentstemcellianism against the media, whom over the past 6 years has covered stem cell stories with a complete disregard for the proven benefits of adult stem cells and an almost conspiracy theory-esque focus on “treatment unusable” embryonic stem cells.

When an “adult stem cells” story came out; there was either no coverage or highly negative coverage.

When an “embryonic stem cells” story came out; the coverage was either positive or in the often times scenario when there was very little positive to say, incredibly optimistic and forward looking.

Alpha Inventions – A Year Later

For Stem Cell Treatments and News, click on the stem cell:

I signed up on AlphaInventions a year ago.  It is a very cool site that lets you see a streaming blog roll in the area of your interest.  Check it out!  http://alphainventions.com It’s one of those hot growing sites that you wish you knew about!

On my best traffic day, when I was typically bringing in traffic in the 1k to 2k range, I had 7,000 visits in one day…reached in part due to the technology made available by alphainventions.  It’s not google level numbers but it sure got my eyes open! As time went on, I became involved in different projects and methods for generating qualified traffic.  So….a year later, what will happen if I post an alpha inventions article?  Will I get my typical 5k per day or will I get 5k + 7k?  Hmmm…..

And btw, this is from my original post on a new category called “Off The Beaten Path”…a section of The Stem Cell Blog where non stem cell related posts will go…a place to let my hair down and recognize that maybe, just maybe…You may think of it as the mutant half child of Robert Frost’s “The Road Not Taken” and Monty Python’s “and now for something completely different!”

“all stem cells and no play” makes David a dull boy.

Enjoy!

David Granovsky

http://repairstemcell.wordpress.com

California Stem Cell Report: LA Times on CIRM Plans to Remain ‘Relevant’

Monday, February 01, 2010

LA Times on CIRM Plans to Remain ‘Relevant’

The changing focus of the California stem cell agency – with its aggressive push towards fast, tangible and marketable results and presumably away from its original emphasis on human embryonic stem cell research – was the focus of a Los Angeles Times article early last month.

The Jan. 10, 2010, piece by Karen Kaplan said,

“Now the institute has a more immediate goal: boosting therapies that are much further along in development and more often rely on less glamorous adult stem cells. It is concentrating its vast financial resources on projects that could cure conditions such as age-related macular degeneration, AIDS, sickle cell disease and various types of cancer.

via California Stem Cell Report: LA Times on CIRM Plans to Remain ‘Relevant’.

Investors.com – California’s Proposition 71 Failure

California’s Proposition 71 Failure

Posted 01/12/2010 06:36 PM ET

Bioethics: Five years after a budget-busting $3 billion was allocated to embryonic stem cell research, there have been no cures, no therapies and little progress. So supporters are embracing research they once opposed.

California’s Proposition 71 was intended to create a $3 billion West Coast counterpart to the National Institutes of Health, empowered to go where the NIH could not — either because of federal policy or funding restraints on biomedical research centered on human embryonic stem cells.

Supporters of the California Stem Cell Research and Cures Initiative, passed in 2004, held out hopes of imminent medical miracles that were being held up only by President Bush’s policy of not allowing federal funding of embryonic stem cell research (ESCR) beyond existing stem cell lines and which involved the destruction of embryos created for that purpose.

Five years later, ESCR has failed to deliver and backers of Prop 71 are admitting failure. The California Institute for Regenerative Medicine, the state agency created to, as some have put it, restore science to its rightful place, is diverting funds from ESCR to research that has produced actual therapies and treatments: adult stem cell research. It not only has treated real people with real results; it also does not come with the moral baggage ESCR does.

To us, this is a classic bait-and-switch, an attempt to snatch success from the jaws of failure and take credit for discoveries and advances achieved by research Prop. 71 supporters once cavalierly dismissed. We have noted how over the years that when funding was needed, the phrase “embryonic stem cells” was used. When actual progress was discussed, the word “embryonic” was dropped because ESCR never got out of the lab.

Prop 71 had a 10-year mandate and by 2008, as miracle cures looked increasingly unlikely, a director was hired for the agency with a track record of bringing discoveries from the lab to the clinic. “If we went 10 years and had no clinical treatments, it would be a failure,” says the institute’s director, Alan Trounson, a stem cell pioneer from Australia. “We need to demonstrate that we are starting a whole new medical revolution.”

The institute is attempting to do that by funding adult stem cell research. Nearly $230 million was handed out this past October to 14 research teams. Notably, only four of those projects involve embryonic stem cells.

Among the recipients, the Los Angeles Times reports, is a group from UCLA and Children’s Hospital in Los Angeles that hopes to cure patients with sickle cell disease by genetically modifying their own blood-forming stem cells to produce healthy red blood cells. Researchers at Cedars-Sinai Medical Center will use their grant to research injecting heart-attack patients with concentrated amounts of their own cardiac stem cells that naturally repair heart tissue.

Dr. Bernadine Healy, director of the National Institutes of Health under Bush 41, wrote in her U.S. News & World Report column recently that “embryonic stem cells, once thought to hold the cure for Alzheimer’s, Parkinson’s and diabetes, are obsolete.”

Even worse, they can be dangerous.

They are difficult to control, to coax into the specific type of tissue desired. Unlike adult stem cells taken from a patient’s own body, ES cells require the heavy use of immunosuppressive drugs. Their use can lead to a form of tumor called a teratoma.

.

…It is ESCR researchers who have politicized science and stood in the way of real progress. We are pleased to see California researchers beginning to put science in its rightful place.

via Investors.com – California’s Proposition 71 Failure.

Bone Marrow Cells May Improve Stem Cell Therapy, Study Finds

Why would they burden the amazing healing properties of bone marrow stem cells with the rejection and tumors associated with embryonic stem cells?  Bone marrow stem cells work already; they don’t need embryonic stem cells…cord blood stem cells work, umbilical cord cells, fat cells, neuro cells….all work already.  ADULT & REPAIR STEM CELLS WORK!  Even Embryonic Stem Cell focused California has finally realized where their efforts should be…

• Cali Prop 71 Fails – Embryonic produce no cures, no therapies and little progress in 5 years

• Cali Now concentrates on (Adult Stem Cell) projects that can cure conditions

It’s like tying an arsonist to someone with a puritan work ethic in the hopes that more work gets done.  Ok, bad analogy but you get the point…

…so, anyone who can come up with an appropriate analogy to illustrate this point gets a free one year subscription to the Stem Cell Newsletter.-dg

Bone Marrow Cells May Improve Stem Cell Therapy, Study Finds??

January 28th 2010 12:00 AM

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Researchers say they have devised a new strategy that increases the likelihood of a recipient’s immune system accepting embryonic stem cell transplants. The strategy involves fusing bone marrow cells to embryonic stem cells. Once fused, the hybrid cells have DNA from both the donor and recipient, raising hopes that immune rejection of embryonic stem cell therapies can be avoided without drugs. The findings appear in the February issue of the FASEB Journal

Although the study holds great promise for future embryonic stem cell therapies, the results may be even more far reaching. The team used two different mouse strains, one as the donor and the other as the recipient. When bone marrow cells were engrafted into the recipient, they tested for the presence of both donor and recipient cells and found three different types of cells: donor cells, recipient cells, and fused cells that had DNA from the donor and recipient…

via Bone Marrow Cells May Improve Stem Cell Therapy, Study Finds.