Adult Stem Cells are at least a foot ahead of Embryonic (and an ankle too)

Adult Stem Cells-

Now Healing Broken Bones-

Foot, Ankle

Posted 7 March, 2009

New Stem Cell Research for Unhealed Bone Fractures

A medical team is reporting new stem cell research using Adult Stem Cells to heal broken bones in the foot and ankle. The Adult Stem Cell product called “Trinity” was used to heal bone fractures  in the foot and ankle of 21 people that failed to connect properly after the initial healing.

Clinical Results of Adult Stem Cells For Unhealed Foot and Ankle Fractures

Dr. Shannon Rush, of Palo Alto Medical Foundation presented his results of using Adult Stem Cells in the Journal of Foot and Ankle Surgery for March, 2009:

A review was conducted of 23 patients who underwent implantation of mesenchymal stem cell allograft for revision foot or ankle surgery. Composed of viable mesenchymal stem cells derived from cadaveric donor tissue, the graft had osteogenic, osteoinductive, and osteoconductive properties, and was capable of direct new bone formation at the site of implantation. In all of the cases, radiographic new bone formation was observed at the area of implantation and a 91.3% union rate was observed, and no evidence of graft rejection or complications associated with implantation were recorded.

Let me try to translate that-  the doctors took 23 patients who had broken bones or previous fractures  in their foot or ankle that did not heal properly (or nonunion is the clinical term).  As a result, they had difficulty and/or pain when walking.

21 out of the 23 patients who were implanted with this adult stem cell product “Trinity” achieved “bone union” and healing which allowed them to walk in regular shoes with little or no pain after their casts were removed.

What is Trinity?

Trinity is a mixture of donated adult stem cells combined with crushed bone from a bone bank.  It’s full name is Trinity Multipotential Cellular Bone Matrix.

I previously covered Trinity and how it was used  for spinal fusions.  Most importantly, Trinity is already approved by the US FDA.

What This Means For Unhealed Bone Fractures

According to the Trinity website:

Trinity is an effective alternative to autograft in virtually all orthopedic applications. Essentially, for every surgical indication where autograft would be selected by a surgeon to be a bone void fill or bone growth stimulator, Trinity can be used. Trinity is not intended to be be used as an autograft “extender.” It is intended to be a substitute for autograft.

An estimated 600,000 Americans suffer from unhealed bone fractures, so for any orthopedists or podiatrists or patients reading this- this is good news for you. Since it is FDA approved, I imagine if you wanted the “Trinity” adult stem cell product, it would be available for use-  “ask your doctor”.

Some of the Repair Stem Cell Institute’s doctors already use adult stem cells for bone fractures

Gmail – from donmargolis.com NONUNION defeated by RSC – dsgrano@gmail.com.

Hyperbaric oxygen therapy gaining in popularity

What does this have to do with stem cells?  Well…for that you are going to have to wait and see.  But rest assured, when you do learn, it will BLOW YOUR MIND!! -dg

Hyperbaric oxygen therapy gaining in popularity

Sat, 28 Feb 2009 6:26p.m.

Doctors have discovered breathing in pure oxygen can give people with wounds that won’t heal a new lease of life.

Hyperbaric oxygen therapy was seen as a last resort for those suffering from injuries that did not respond to treatment, but at a privately run clinic its success has meant it is gaining in popularity.

After part of his leg was amputated four years ago, Malcolm Fleck was in agony and could hardly move. His stump was ulcerated and infected and as a last resort he tried hyperbaric oxygen therapy.

“I had 11 operations in four years and this is getting rid of it where antibiotics and so-called well, modern medicine can’t,” Mr Fleck says.

The technology has been used by divers suffering from the bends for decades, but now it is becoming an accepted part of mainstream medicine.

Patients sit inside the chamber breathing pure oxygen through helmets under pressure. It is this combination that accelerates healing by up to 80 percent.

With titanium implants inserted into her neck, Paparoa schoolteacher Audrey Campbell was in constant pain. She could not stand, let a long work.

Having tried numerous treatments in the past she was cynical at first, but now she’s a convert.

“I wouldn’t have believed it, it’s a really positive experience,” Ms Campbell says.

Both patients are now breathing easy as the pain subsides and their recovery takes off.

via 3 News > Science-Tech > Story > Hyperbaric oxygen therapy gaining in popularity.

Study: Stem cell transplants could reverse MS – Cloning and stem cells- msnbc.com

MS - Deterioration of Myelin Sheath

81 percent of patients showed signs of improvement with the treatment

Meanwhile, there are 4 treatment centers around the world who have been treating MS for years with adult stem cells. – dg

updated 8:15 p.m. ET, Thurs., Jan. 29, 2009

CHICAGO – U.S. researchers have reversed multiple sclerosis symptoms in early stage patients by using bone marrow stem cell transplants to reset the immune system, they said on Thursday.

Some 81 percent of patients in the early phase study showed signs of improvement with the treatment, which used chemotherapy to destroy the immune system, and injections of the patient’s bone marrow cells taken beforehand to rebuild it.

“We just start over with new cells from the stem cells,” said Dr. Richard Burt of Northwestern University in Chicago, whose study appears in the journal Lancet Neurology…

via Study: Stem cell transplants could reverse MS – Cloning and stem cells- msnbc.com.

CATCH UP! – New stem cell technique brings Parkinson’s cure closer

Chasing a cure for Neurological Disease

“New” stem cell technique brings Parkinson’s cure “closer”???? CATCH UP!  There are treatment centers around  the world that have been treating Parkinson’s disease with adult stem cells for years. -dg

New stem cell technique brings Parkinson’s cure closer

By David Derbyshire

Last updated at 11:07 AM on 06th March 2009

Unlike previous attempts to create stem cells, the American team of researchers did not need to create and destroy human embryos

A technique that turns human skin into healthy brain cells could offer hope to thousands of Parkinson’s disease patients, scientists said today.

Researchers believe that injections of these cells could reverse damage caused by the degenerative brain disease – and ease some of its most distressing symptoms.

It is the first time that scientists have ‘reprogrammed’ ordinary skin cells into becoming stem cells using this technique – and then turned them into healthy brain cells.

The brain cells produced dopamine, the chemical lacking in people suffering form Parkinson’s disease.

Unlike previous attempts to create stem cells, the American team of researchers did not need to create and destroy human embryos.

They were also able to make the cells free of cancer causing genes – a massive problem with previous experiments.

via New stem cell technique brings Parkinson’s cure closer | Mail Online.

Lions and puppys and horseys, oh my!

All the lion, dog and horse posts to date:

http://repairstemcell.wordpress.com/2009/08/09/arthritic-dog-injected-with-stem-cells-owen-sound-sun-times-ontario-ca/

http://repairstemcell.wordpress.com/2009/03/05/video-using-dog-fat-cells-to-treat-arthritis-nbc13com/

http://repairstemcell.wordpress.com/2009/03/01/will-rover-outlive-grandma/

http://repairstemcell.wordpress.com/2009/02/27/equine-clinic-is-full-service-care-for-hoofed-friends-thecaliforniancom-the-salinas-californian/

http://repairstemcell.wordpress.com/2009/02/18/mountain-lion-receives-stem-cell-therapy/

http://repairstemcell.wordpress.com/2009/02/18/adult-stem-cell-therapy-for-dogs-too/

http://repairstemcell.wordpress.com/2009/02/13/stem-cell-treatment-heals-fremont-police-dog-20909-san-francisco-news-abc7newscom-3/

http://repairstemcell.wordpress.com/2009/02/12/skorean-firm-dogs-cloned-using-stem-cells/

http://repairstemcell.wordpress.com/2009/02/10/rovers-do-over/

http://repairstemcell.wordpress.com/2009/02/27/horse-racing-horse-racing-samantha-miss-has-stem-cell-treatment/

http://repairstemcell.wordpress.com/2009/02/26/prp-part-2-horses-and-humans/

http://repairstemcell.wordpress.com/2009/02/26/prp-part-3-horsing-around-with-stem-cells/

030709 – AlphaInventions gives you a dose of stem cells

No surprise here.  Most of the news is about Obama lifting the ban on embryonic stem cell research…a relatively insignificant news item to the multitude of dying and debilitated American because as the father of embryonic research stated: there will be no treatments from embryonics for 10-50 years. -dg

March 7, 2009 - Obama's Big News

Your daily dose of stem cells…

brought to you by our friends at AlphaInventions.com

Google:

•   Stem-cell policy change liberating to researchers – KVUE March 7, 2009
•   Vatican daily slams embryonic stem cell research – Times of India March 7, 2009
•   Obama to open up stem cell research – Kazakhstan News March 7, 2009
•   Geron Surges after US Stem-cell News – MarketWatch March 7, 2009
•   New Life For Stem-Cell Funding Boosts Biotech Forbes
•   Obama Stem Cell Decision Called ‘Deadly Executive Order’

DonMargolis.com:

• Adult Stem Cells- Now Healing Broken Bones- Foot, Ankle March 7, 2009

CellNews:

• Stem Cell Breakthrough Gives New Hope to Sufferers of Muscle-wasting Diseases March 7, 2009
• How Stem Cells Develop Into Blood Cells March 7, 2009
• Stem Cells That Repair Injured Muscles March 7, 2009
• The Making of an Intestinal Stem Cell March 7, 2009
• Virus-free Embryonic-like Stem Cells Made from Skin March 7, 2009
• Obama to Reverse Embryonic Stem Cell Ban March 7, 2009